PPP2R2B and TOP1

  • Number of citations of the paper that reports this interaction (PMID 12549820)
  • 1
  • Data Source:
  • BioGRID (unspecified method)

PPP2R2B

TOP1

Gene Name protein phosphatase 2, regulatory subunit B, beta topoisomerase (DNA) I
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol dependence ( 19581569)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-Protein Interactions 5 interactors: CHEK2 KLHL15 RAC1 TOP1 TP53 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I
Entrez ID 5521 7150
HPRD ID 05059 00535
Ensembl ID ENSG00000156475 ENSG00000198900
Uniprot IDs Q00005 P11387
PDB IDs 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
allele  arg72pro  associates  curves  died  ethnically  gender  genotyped  genotypes  interested  kaplan  lifespan  lived  llis  log  longevity  mdm4  meier  rank  respective  rs1042522  rs1563828  rs2279744  rs319217  rs4245739  snp309  snp31826  snp34091  snps 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Difference) ?
allele  arg72pro  associates  curves  died  ethnically  gender  genotyped  genotypes  interested  kaplan  lifespan  lived  llis  log  longevity  mdm4  meier  rank  respective  rs1042522  rs1563828  rs2279744  rs319217  rs4245739  snp309  snp31826  snp34091  snps 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Intersection) ?