PPP2R2B and KLHL15

Number of citations of the paper that reports this interaction (PMID 23135275)
0

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		PPP2R2B	KLHL15
Gene Name		protein phosphatase 2, regulatory subunit B, beta	kelch-like family member 15
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Mitochondrion Mitochondrial Outer Membrane Cytoskeleton
	Molecular Function	Protein Binding Protein Phosphatase Type 2A Regulator Activity
	Biological Process	Apoptotic Process Signal Transduction Regulation Of Catalytic Activity	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Alcohol dependence ( 19581569) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-Protein Interactions		5 interactors: CHEK2 KLHL15 RAC1 TOP1 TP53	1 interactors: PPP2R2B
Entrez ID		5521	80311
HPRD ID		05059	09957
Ensembl ID		ENSG00000156475	ENSG00000174010
Uniprot IDs		Q00005	Q96M94
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA Replication Replicative Senescence Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Negative Regulation Of DNA Replication Response To Gamma Radiation Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cell Aging Viral Process Response To Osmotic Stress Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of DNA Metabolic Process Mitotic DNA Integrity Checkpoint Signal Transduction Involved In Intra-S DNA Damage Checkpoint Response To Ionizing Radiation Double-strand Break Repair DNA Damage Checkpoint Negative Regulation Of Macromitophagy Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Oligodendrocyte Apoptotic Process Regulation Of Reactive Oxygen Species Metabolic Process Mitotic Cell Cycle Checkpoint Positive Regulation Of Protein Complex Assembly Circadian Rhythm Engulfment Of Apoptotic Cell Negative Regulation Of Helicase Activity Intrinsic Apoptotic Signaling Pathway Apoptotic Process Protein Complex Assembly Mast Cell Chemotaxis DNA Metabolic Process Negative Regulation Of Mitotic Cell Cycle Response To Abiotic Stimulus Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Embryo Development Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging DNA Conformation Change Mitochondrial DNA Repair Organelle Organization Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment
Tagcloud ?		allele arg72pro associates curves died ethnically gender genotyped genotypes interested kaplan lifespan lived llis log longevity mdm4 meier rank respective rs1042522 rs1563828 rs2279744 rs319217 rs4245739 snp309 snp31826 snp34091 snps
Tagcloud (Difference) ?		allele arg72pro associates curves died ethnically gender genotyped genotypes interested kaplan lifespan lived llis log longevity mdm4 meier rank respective rs1042522 rs1563828 rs2279744 rs319217 rs4245739 snp309 snp31826 snp34091 snps
Tagcloud (Intersection) ?