XRN1 and UPF1

  • Number of citations of the paper that reports this interaction (PMID 14527413)
  • 102
  • Data Source:
  • HPRD (in vivo)

XRN1

UPF1

Gene Name 5-3 exoribonuclease 1 UPF1 regulator of nonsense transcripts homolog (yeast)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 62 interactors: ALDOA ANGPTL6 AP1G2 ATP5G2 B3GALT6 BAG6 C1GALT1 CBX5 CCT5 CD97 CENPBD1 CHD4 CTSB CTSH DCP1A DCP1B DNASE2 DPP7 DXO EXOSC1 EXOSC10 EXOSC6 EXOSC8 FADS1 GLMP HEATR1 HNRNPA1 KATNB1 LDHA LEPR LGALS3BP LINC01541 LSM4 MAN2C1 MFSD5 MTCH2 NDUFA13 NDUFB10 NDUFB9 PABPC4 PLEKHG2 POLD2 PPP2CA PRADC1 PSMB5 RBMX RNF187 SDHB SKIV2L SKIV2L2 SMARCD2 SNHG1 SPATA20 SRRM2 STAM2 TMEM50A UPF1 UPF2 UPF3B VWA5B2 WAPAL ZFP36 31 interactors: ABHD16A ACSS2 ATR CSNK2B DCP1A DCP2 DXO EIF3A EIF3B EIF4A3 EXOSC2 EXOSC4 GNPTG GSPT2 HIRA LSM8 NADSYN1 NDRG1 NDUFB10 PLEKHA5 PLEKHB2 POLR2A RHOXF2 RPRD2 SMG1 SMG5 STAU1 UPF2 UPF3A UPF3B XRN1
Entrez ID 54464 5976
HPRD ID 10470 03254
Ensembl ID ENSG00000114127 ENSG00000005007
Uniprot IDs Q8IZH2 Q92900
PDB IDs 2GJK 2GK6 2GK7 2IYK 2WJV 2WJY 2XZO 2XZP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alters  artificial  avirulence  bisexual  capsule  changing  constantly  coordinated  corresponds  cryptococcosis  cryptococcus  encountering  environments  exonuclease  habitat  impairs  interdependent  invertebrate  lac1  mating  melanin  neoformans  opportunistic  rrp44  uni  virulence  xrn1delta  xrn1p  xrn2 
aav9  adeno  als  amyotrophic  cord  decay  empty  exerts  forelimb  green  helps  implicate  mycupf1  nmd  nonsense  otherwise  paralysis  quadriplegic  recapitulate  reproducible  respective  spinal  tdp  titrated  transactive  twofold  upframeshift  validate  vector 
Tagcloud (Difference) ?
alters  artificial  avirulence  bisexual  capsule  changing  constantly  coordinated  corresponds  cryptococcosis  cryptococcus  encountering  environments  exonuclease  habitat  impairs  interdependent  invertebrate  lac1  mating  melanin  neoformans  opportunistic  rrp44  uni  virulence  xrn1delta  xrn1p  xrn2 
aav9  adeno  als  amyotrophic  cord  decay  empty  exerts  forelimb  green  helps  implicate  mycupf1  nmd  nonsense  otherwise  paralysis  quadriplegic  recapitulate  reproducible  respective  spinal  tdp  titrated  transactive  twofold  upframeshift  validate  vector 
Tagcloud (Intersection) ?