XRN1 and RBMX

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		XRN1	RBMX
Gene Name		5-3 exoribonuclease 1	RNA binding motif protein, X-linked
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Intermediate Filament Cytoskeleton	Extracellular Space Nucleus Nucleoplasm Nuclear Euchromatin Membrane Ribonucleoprotein Complex Supraspliceosomal Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding Exonuclease Activity Protein Binding Poly(A) RNA Binding	Nucleotide Binding Core Promoter Binding Chromatin Binding RNA Binding MRNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process Gene Expression RRNA Catabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear MRNA Surveillance Histone MRNA Catabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription From RNA Polymerase II Promoter Membrane Protein Ectodomain Proteolysis RNA Splicing Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Homooligomerization Cellular Response To Interleukin-1
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements mRNA decay by 5' to 3' exoribonuclease Tristetraprolin (TTP) destabilizes mRNA Deadenylation-dependent mRNA decay Butyrate Response Factor 1 (BRF1) destabilizes mRNA	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: ALDOA ANGPTL6 AP1G2 ATP5G2 B3GALT6 BAG6 C1GALT1 CBX5 CCT5 CD97 CENPBD1 CHD4 CTSB CTSH DCP1A DCP1B DNASE2 DPP7 DXO EXOSC1 EXOSC10 EXOSC6 EXOSC8 FADS1 GLMP HEATR1 HNRNPA1 KATNB1 LDHA LEPR LGALS3BP LINC01541 LSM4 MAN2C1 MFSD5 MTCH2 NDUFA13 NDUFB10 NDUFB9 PABPC4 PLEKHG2 POLD2 PPP2CA PRADC1 PSMB5 RBMX RNF187 SDHB SKIV2L SKIV2L2 SMARCD2 SNHG1 SPATA20 SRRM2 STAM2 TMEM50A UPF1 UPF2 UPF3B VWA5B2 WAPAL ZFP36	34 interactors: APOBEC3C CCDC33 CIRBP CLK3 CSNK2A1 FAM103A1 FUS FXR2 HNRNPK IL7R ITSN2 JAK2 KHDRBS1 KHDRBS2 KHDRBS3 LNX1 MAGOHB NABP1 NFE2L2 PRR3 PSMF1 RBM3 RBM7 RBMY1A1 RBMY1F ROBO3 SNRPA SOCS3 SORBS3 SREK1 STAT5A TRA2B XRN1 ZNF490
Entrez ID		54464	27316
HPRD ID		10470	02186
Ensembl ID		ENSG00000114127	ENSG00000147274
Uniprot IDs		Q8IZH2	P38159
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Metabolic Process Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process Catabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RRNA Processing RNA Processing RRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Generation Of Precursor Metabolites And Energy Ribosome Biogenesis Cellular Metabolic Process Respiratory Electron Transport Chain Electron Transport Chain RNA Splicing RNA Localization RNA Export From Nucleus Gene Expression Cellular Respiration MRNA Processing Energy Derivation By Oxidation Of Organic Compounds Ribonucleoprotein Complex Biogenesis Cellular Process Nuclear MRNA Surveillance Metabolic Process Nuclear Export MRNA Transport RNA Surveillance MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone MRNA Catabolic Process ATP Metabolic Process Dosage Compensation By Inactivation Of X Chromosome Cellular Response To Thyroid Hormone Stimulus RNA Transport RNA Destabilization Dosage Compensation MRNA Export From Nucleus Posttranscriptional Regulation Of Gene Expression	MRNA Metabolic Process RNA Processing MRNA Processing Gene Expression RNA Splicing RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Regulation Of Gene Expression Response To Growth Hormone JAK-STAT Cascade Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Translation Positive Regulation Of Gene Expression Positive Regulation Of Protein Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Metabolic Process Regulation Of RNA Splicing Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Response To Interferon-gamma Regulation Of Translation Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Cytokine Stimulus Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Mitotic Cell Cycle Checkpoint Histone H3-Y41 Phosphorylation Host Programmed Cell Death Induced By Symbiont Positive Regulation Of Mast Cell Differentiation Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Death Regulation Of Mitotic Cell Cycle Response To Cold Response To Cytokine Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Mineralocorticoid Receptor Signaling Pathway Interleukin-7-mediated Signaling Pathway Positive Regulation Of RNA Export From Nucleus Cytokine-mediated Signaling Pathway
Tagcloud ?		alters artificial avirulence bisexual capsule changing constantly coordinated corresponds cryptococcosis cryptococcus encountering environments exonuclease habitat impairs interdependent invertebrate lac1 mating melanin neoformans opportunistic rrp44 uni virulence xrn1delta xrn1p xrn2	122c 2012cb944901 9qh azoospermia blimp1 dazl ddx4 declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 stella sublines talents vasa xq znf
Tagcloud (Difference) ?		alters artificial avirulence bisexual capsule changing constantly coordinated corresponds cryptococcosis cryptococcus encountering environments exonuclease habitat impairs interdependent invertebrate lac1 mating melanin neoformans opportunistic rrp44 uni virulence xrn1delta xrn1p xrn2	122c 2012cb944901 9qh azoospermia blimp1 dazl ddx4 declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 stella sublines talents vasa xq znf
Tagcloud (Intersection) ?