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IDO1
Description
indoleamine 2,3-dioxygenase 1
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Smooth Muscle Contractile Fiber
Stereocilium Bundle
Molecular Function
Tryptophan 2,3-dioxygenase Activity
Electron Transfer Activity
Oxidoreductase Activity
Heme Binding
Indoleamine 2,3-dioxygenase Activity
Metal Ion Binding
Dioxygenase Activity
Biological Process
Immune System Process
Positive Regulation Of T Cell Tolerance Induction
Positive Regulation Of Chronic Inflammatory Response
Positive Regulation Of Type 2 Immune Response
L-tryptophan Catabolic Process
Inflammatory Response
Female Pregnancy
L-tryptophan Catabolic Process To Kynurenine
Quinolinate Biosynthetic Process
Response To Lipopolysaccharide
Negative Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Multicellular Organismal Response To Stress
Kynurenic Acid Biosynthetic Process
'de Novo' NAD+ Biosynthetic Process From L-tryptophan
Swimming Behavior
T Cell Proliferation
Negative Regulation Of T Cell Proliferation
Positive Regulation Of Apoptotic Process
Regulation Of Activated T Cell Proliferation
Negative Regulation Of T Cell Apoptotic Process
Positive Regulation Of T Cell Apoptotic Process
Pathways
Tryptophan catabolism
Drugs
Nitric Oxide
Cannabidiol
Medical Cannabis
Nabiximols
Diseases
GWAS
Novel Interacting Genes
6 novel interacting genes:
ADRB3
DCTN6
DUSP4
RBPMS
SFRP1
SLC20A2
Interacting Genes
5 interacting genes:
APP
DDX24
FBXL17
PPP1R16A
TERF2IP
Entrez ID
3620
HPRD ID
00935
Ensembl ID
ENSG00000131203
Uniprot IDs
A0A348GSI3
P14902
PDB IDs
2D0T
2D0U
4PK5
4PK6
4U72
4U74
5EK2
5EK3
5EK4
5ETW
5WHR
5WMU
5WMV
5WMW
5WMX
5WN8
5XE1
6AZU
6AZV
6AZW
6CXU
6CXV
6DPQ
6DPR
6E35
6E40
6E41
6E42
6E43
6E44
6E45
6E46
6F0A
6KOF
6KPS
6KW7
6MQ6
6O3I
6PU7
6PZ1
6R63
6UBP
6V52
6WJY
6WPE
6X5Y
7A62
7AH4
7AH5
7AH6
7B1O
7E0O
7E0P
7E0Q
7E0S
7E0T
7E0U
7M63
7M7D
7NGE
7P0N
7P0R
7RRB
7RRC
7RRD
7YXT
7Z2L
7ZV3
8ABX
8FUR
8I7L
8U5I
9ESB
9ESC
9ESE
9ESG
Enriched GO Terms of Interacting Partners
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