IDO1

Gene Name		indoleamine 2,3-dioxygenase 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol Smooth Muscle Contractile Fiber Stereocilium Bundle
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Electron Carrier Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding
	Biological Process	Cytokine Production Involved In Inflammatory Response Positive Regulation Of T Cell Tolerance Induction Positive Regulation Of Chronic Inflammatory Response Positive Regulation Of Type 2 Immune Response Tryptophan Catabolic Process Female Pregnancy Tryptophan Catabolic Process To Kynurenine Response To Lipopolysaccharide Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Multicellular Organismal Response To Stress Kynurenic Acid Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Swimming Behavior Negative Regulation Of T Cell Proliferation Small Molecule Metabolic Process Regulation Of Activated T Cell Proliferation Oxidation-reduction Process Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of T Cell Apoptotic Process
Pathways		Tryptophan catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: APP DDX24 PPP1R16A TERF2IP
Entrez ID		3620
HPRD ID		00935
Ensembl ID
Uniprot IDs		P14902
PDB IDs		2D0T 2D0U
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Recombination At Telomere Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Protein Localization To Chromosome, Telomeric Region Axon Choice Point Recognition Neuron Remodeling Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Double-strand Break Repair Via Homologous Recombination Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance RNA Metabolic Process RNA-dependent DNA Replication Copper Ion Homeostasis Suckling Behavior Negative Regulation Of DNA Recombination Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Double-strand Break Repair Protein Localization To Chromosome Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Telomere Maintenance Via Telomere Lengthening Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Regulation Of DNA Repair Visual Behavior Neuron Death Heterocycle Metabolic Process
Tagcloud ?		anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 cd8a ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic igkc immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable