Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
EXOSC10 and MPHOSPH6
Number of citations of the paper that reports this interaction (PMID
15231747
)
44
Data Source:
HPRD
(two hybrid)
EXOSC10
MPHOSPH6
Gene Name
exosome component 10
M-phase phosphoprotein 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Membrane
Transcriptionally Active Chromatin
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleus
Nucleolus
Cytoplasm
Molecular Function
Nucleotide Binding
Exoribonuclease Activity
Protein Binding
3'-5' Exonuclease Activity
Poly(A) RNA Binding
RNA Binding
Protein Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Maturation Of 5.8S RRNA
Nuclear-transcribed MRNA Catabolic Process
Dosage Compensation By Inactivation Of X Chromosome
Nuclear MRNA Surveillance
CUT Catabolic Process
Nuclear Polyadenylation-dependent RRNA Catabolic Process
Histone MRNA Catabolic Process
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Maturation Of 5.8S RRNA
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
35 interactors:
ALDH1B1
B9D1
CHPF
CIB1
DIS3
DXO
EIF3M
EXOSC4
EXOSC5
EXOSC6
EXOSC7
EXOSC8
FERMT3
FOXRED1
IMMT
LCAT
LSM2
LSM8
MPHOSPH6
MPP6
NOMO1
NOMO2
PTGES2
RPE
RUVBL2
SCRIB
SKIV2L
SSRP1
TARDBP
TOX4
UPF2
USP16
USP21
XRN1
XRN2
24 interactors:
AATF
APLP1
ARHGAP18
C14orf1
DNM2
DYNLRB1
EIF3G
EXOSC10
FTL
GDF9
KNSTRN
LRIF1
NUPR1
PARN
RBM48
RPS20
SKIV2L2
SMARCA4
SNX9
THOP1
TLE1
TP53
UNC119
ZHX1
Entrez ID
5394
10200
HPRD ID
16180
16111
Ensembl ID
ENSG00000171824
ENSG00000135698
Uniprot IDs
Q01780
Q96G78
Q99547
PDB IDs
2CPR
3SAF
3SAG
3SAH
Enriched GO Terms of Interacting Partners
?
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
RNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
MRNA Metabolic Process
RRNA Metabolic Process
RRNA Processing
Aromatic Compound Catabolic Process
Cellular Macromolecule Catabolic Process
Ribosome Biogenesis
Ribonucleoprotein Complex Biogenesis
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Catabolic Process
RNA Metabolic Process
NcRNA Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nuclear MRNA Surveillance
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA Deamination
RNA Surveillance
Nucleic Acid Phosphodiester Bond Hydrolysis
RNA Phosphodiester Bond Hydrolysis
Gene Expression
Maturation Of 5.8S RRNA
Histone MRNA Catabolic Process
RRNA Catabolic Process
Cellular Metabolic Process
DNA Modification
Protein K63-linked Deubiquitination
Histone Deubiquitination
Histone MRNA Metabolic Process
DNA Metabolic Process
Chromatin Modification
Regulation Of Cell Adhesion Mediated By Integrin
Positive Regulation Of Male Germ Cell Proliferation
Metabolic Process
Chromatin Remodeling
MRNA Processing
Regulation Of RNA Stability
Chromatin Organization
Thrombopoietin-mediated Signaling Pathway
Posttranscriptional Regulation Of Gene Expression
Histone H2A K63-linked Deubiquitination
Regulation Of Male Germ Cell Proliferation
Endomitotic Cell Cycle
Gene Expression
RNA Metabolic Process
Regulation Of Female Gonad Development
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Metabolic Process
Maturation Of 5.8S RRNA
Positive Regulation Of Protein Oligomerization
Ribonucleoprotein Complex Biogenesis
Regulation Of Cell Growth
Endocytosis
Regulation Of Protein Oligomerization
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Mitotic Cell Cycle Process
Nuclear-transcribed MRNA Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Negative Regulation Of Cell Growth
MRNA Catabolic Process
Negative Regulation Of Fibroblast Proliferation
Nitrogen Compound Metabolic Process
Mitotic Cell Cycle
Positive Regulation Of Metabolic Process
Regulation Of Protein Metabolic Process
Cell Division
Regulation Of Gene Expression
RNA Catabolic Process
Ribosome Biogenesis
Regulation Of Metabolic Process
Mitotic Cytokinesis
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Clathrin-mediated Endocytosis
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Membrane Organization
Growth
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Protein Modification Process
Negative Regulation Of Growth
Nucleobase-containing Compound Metabolic Process
Regulation Of Cellular Component Organization
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
RNA Processing
Regulation Of Apoptotic Process
Negative Regulation Of Macromitophagy
Negative Regulation Of Membrane Tubulation
Lipid Tube Assembly
Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis
Negative Regulation Of Caveolin-mediated Endocytosis
Oocyte Growth
Tagcloud
?
18s
adopt
assumed
candidates
carry
defects
exosome
extensively
functionally
fundamental
hela
homolog
its2
itss
nucleolar
polycistronic
posing
precede
precursors
processing
recruit
ribosomopathies
rnas
rrna
rrnas
rrp6
spacers
transcribed
yeast
Tagcloud (Difference)
?
18s
adopt
assumed
candidates
carry
defects
exosome
extensively
functionally
fundamental
hela
homolog
its2
itss
nucleolar
polycistronic
posing
precede
precursors
processing
recruit
ribosomopathies
rnas
rrna
rrnas
rrp6
spacers
transcribed
yeast
Tagcloud (Intersection)
?