EXOSC10 and ALDH1B1

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		EXOSC10	ALDH1B1
Gene Name		exosome component 10	aldehyde dehydrogenase 1 family, member B1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Transcriptionally Active Chromatin	Nucleoplasm Mitochondrion Mitochondrial Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleotide Binding Exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity Poly(A) RNA Binding	Aldehyde Dehydrogenase (NAD) Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Nuclear MRNA Surveillance CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Histone MRNA Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Carbohydrate Metabolic Process Ethanol Catabolic Process Oxidation-reduction Process
Pathways
Drugs			NADH
Diseases
GWAS
Protein-Protein Interactions		35 interactors: ALDH1B1 B9D1 CHPF CIB1 DIS3 DXO EIF3M EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 FERMT3 FOXRED1 IMMT LCAT LSM2 LSM8 MPHOSPH6 MPP6 NOMO1 NOMO2 PTGES2 RPE RUVBL2 SCRIB SKIV2L SSRP1 TARDBP TOX4 UPF2 USP16 USP21 XRN1 XRN2	3 interactors: EXOSC10 FABP2 XRN2
Entrez ID		5394	219
HPRD ID		16180	00005
Ensembl ID		ENSG00000171824	ENSG00000137124
Uniprot IDs		Q01780 Q96G78	P30837
PDB IDs		2CPR 3SAF 3SAG 3SAH
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Metabolic Process RRNA Metabolic Process RRNA Processing Aromatic Compound Catabolic Process Cellular Macromolecule Catabolic Process Ribosome Biogenesis Ribonucleoprotein Complex Biogenesis RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Catabolic Process RNA Metabolic Process NcRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear MRNA Surveillance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Deamination RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Gene Expression Maturation Of 5.8S RRNA Histone MRNA Catabolic Process RRNA Catabolic Process Cellular Metabolic Process DNA Modification Protein K63-linked Deubiquitination Histone Deubiquitination Histone MRNA Metabolic Process DNA Metabolic Process Chromatin Modification Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Male Germ Cell Proliferation Metabolic Process Chromatin Remodeling MRNA Processing Regulation Of RNA Stability Chromatin Organization Thrombopoietin-mediated Signaling Pathway Posttranscriptional Regulation Of Gene Expression Histone H2A K63-linked Deubiquitination Regulation Of Male Germ Cell Proliferation Endomitotic Cell Cycle	RNA Phosphodiester Bond Hydrolysis, Exonucleolytic RNA Phosphodiester Bond Hydrolysis Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis Nuclear MRNA Surveillance RNA Surveillance Aromatic Compound Catabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Intracellular MRNA Localization RRNA Catabolic Process Dosage Compensation MRNA Metabolic Process RNA Processing Maturation Of 5.8S RRNA Histone MRNA Metabolic Process Cellular Macromolecule Catabolic Process DNA Catabolic Process, Exonucleolytic DNA-templated Transcription, Termination Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Digestion RRNA Processing Catabolic Process RRNA Metabolic Process DNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process Cell Growth RNA Localization MRNA Catabolic Process
Tagcloud ?		18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Difference) ?		18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Intersection) ?