EXOSC10 and DXO

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		EXOSC10	DXO
Gene Name		exosome component 10	decapping exoribonuclease
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Transcriptionally Active Chromatin	Nucleoplasm Cytoplasm Plasma Membrane
	Molecular Function	Nucleotide Binding Exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity Poly(A) RNA Binding	Nucleotide Binding Magnesium Ion Binding MRNA Binding 5'-3' Exonuclease Activity RNA Pyrophosphohydrolase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Nuclear MRNA Surveillance CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Histone MRNA Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	MRNA Catabolic Process Metabolic Process RNA Destabilization Nuclear MRNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: ALDH1B1 B9D1 CHPF CIB1 DIS3 DXO EIF3M EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 FERMT3 FOXRED1 IMMT LCAT LSM2 LSM8 MPHOSPH6 MPP6 NOMO1 NOMO2 PTGES2 RPE RUVBL2 SCRIB SKIV2L SSRP1 TARDBP TOX4 UPF2 USP16 USP21 XRN1 XRN2	8 interactors: EXOSC10 EXOSC4 EXOSC7 FLOT2 PRMT6 UPF1 XRN1 XRN2
Entrez ID		5394	1797
HPRD ID		16180	16186
Ensembl ID		ENSG00000171824	ENSG00000204348
Uniprot IDs		Q01780 Q96G78	O77932
PDB IDs		2CPR 3SAF 3SAG 3SAH
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Metabolic Process RRNA Metabolic Process RRNA Processing Aromatic Compound Catabolic Process Cellular Macromolecule Catabolic Process Ribosome Biogenesis Ribonucleoprotein Complex Biogenesis RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Catabolic Process RNA Metabolic Process NcRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear MRNA Surveillance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Deamination RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Gene Expression Maturation Of 5.8S RRNA Histone MRNA Catabolic Process RRNA Catabolic Process Cellular Metabolic Process DNA Modification Protein K63-linked Deubiquitination Histone Deubiquitination Histone MRNA Metabolic Process DNA Metabolic Process Chromatin Modification Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Male Germ Cell Proliferation Metabolic Process Chromatin Remodeling MRNA Processing Regulation Of RNA Stability Chromatin Organization Thrombopoietin-mediated Signaling Pathway Posttranscriptional Regulation Of Gene Expression Histone H2A K63-linked Deubiquitination Regulation Of Male Germ Cell Proliferation Endomitotic Cell Cycle	Histone MRNA Catabolic Process RNA Catabolic Process Histone MRNA Metabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Nuclear MRNA Surveillance MRNA Catabolic Process Aromatic Compound Catabolic Process RNA Surveillance MRNA Metabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Cellular Macromolecule Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Dosage Compensation By Inactivation Of X Chromosome Catabolic Process Dosage Compensation RRNA Catabolic Process RNA Metabolic Process RRNA Processing Gene Expression NcRNA Metabolic Process Maturation Of 5.8S RRNA Ribosome Biogenesis Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Nitrogen Compound Metabolic Process DNA Metabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Histone H3-R2 Methylation RNA Localization Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Gene Expression, Epigenetic DNA Deamination Intracellular MRNA Localization Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Translational Termination Histone H4-R3 Methylation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation
Tagcloud ?		18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast	1beta bioreactor cd11b cdh5 constructs dataset dioxepan ec ecs engineered hif immunodeficient immunofluorescent implanted lactide leukocyte leukocytes lla migrating msc mscs multipotent pecam retrieved scaffolds subcutaneously toll transmigration umbilical
Tagcloud (Difference) ?		18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast	1beta bioreactor cd11b cdh5 constructs dataset dioxepan ec ecs engineered hif immunodeficient immunofluorescent implanted lactide leukocyte leukocytes lla migrating msc mscs multipotent pecam retrieved scaffolds subcutaneously toll transmigration umbilical
Tagcloud (Intersection) ?