EXOSC10 and RPE

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EXOSC10	RPE
Gene Name		exosome component 10	ribulose-5-phosphate-3-epimerase
Image
Gene Ontology Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Transcriptionally Active Chromatin	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity Poly(A) RNA Binding	Ribulose-phosphate 3-epimerase Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Nuclear MRNA Surveillance CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Histone MRNA Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Carbohydrate Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Pathogenesis Pentose Catabolic Process Cellular Carbohydrate Metabolic Process Small Molecule Metabolic Process
Pathways			Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates Pentose phosphate pathway (hexose monophosphate shunt)
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: ALDH1B1 B9D1 CHPF CIB1 DIS3 DXO EIF3M EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 FERMT3 FOXRED1 IMMT LCAT LSM2 LSM8 MPHOSPH6 MPP6 NOMO1 NOMO2 PTGES2 RPE RUVBL2 SCRIB SKIV2L SSRP1 TARDBP TOX4 UPF2 USP16 USP21 XRN1 XRN2	1 interactors: EXOSC10
Entrez ID		5394	6120
HPRD ID		16180	01608
Ensembl ID		ENSG00000171824
Uniprot IDs		Q01780 Q96G78	B4E016 C9JPQ7 Q96AT9
PDB IDs		2CPR 3SAF 3SAG 3SAH	3OVP 3OVQ 3OVR 3QC3
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Metabolic Process RRNA Metabolic Process RRNA Processing Aromatic Compound Catabolic Process Cellular Macromolecule Catabolic Process Ribosome Biogenesis Ribonucleoprotein Complex Biogenesis RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Catabolic Process RNA Metabolic Process NcRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear MRNA Surveillance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Deamination RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Gene Expression Maturation Of 5.8S RRNA Histone MRNA Catabolic Process RRNA Catabolic Process Cellular Metabolic Process DNA Modification Protein K63-linked Deubiquitination Histone Deubiquitination Histone MRNA Metabolic Process DNA Metabolic Process Chromatin Modification Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Male Germ Cell Proliferation Metabolic Process Chromatin Remodeling MRNA Processing Regulation Of RNA Stability Chromatin Organization Thrombopoietin-mediated Signaling Pathway Posttranscriptional Regulation Of Gene Expression Histone H2A K63-linked Deubiquitination Regulation Of Male Germ Cell Proliferation Endomitotic Cell Cycle	Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Nuclear MRNA Surveillance RNA Surveillance Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Intracellular MRNA Localization Dosage Compensation RRNA Catabolic Process Maturation Of 5.8S RRNA Histone MRNA Metabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA Phosphodiester Bond Hydrolysis RRNA Processing RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process RNA Catabolic Process Ribosome Biogenesis Regulation Of Gene Expression, Epigenetic Nucleic Acid Phosphodiester Bond Hydrolysis Ribonucleoprotein Complex Biogenesis Aromatic Compound Catabolic Process NcRNA Metabolic Process MRNA Metabolic Process RNA Processing
Tagcloud ?		18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast	brdu bromo deoxyuridine digestion doubling doublings galactosidase hinfi inverse kb labeled macular maculopathy nondividing passage passaged pdl pigment prove replicative retinal rsai senescence senescent serially shortening stained studying telomere
Tagcloud (Difference) ?		18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast	brdu bromo deoxyuridine digestion doubling doublings galactosidase hinfi inverse kb labeled macular maculopathy nondividing passage passaged pdl pigment prove replicative retinal rsai senescence senescent serially shortening stained studying telomere
Tagcloud (Intersection) ?