MPHOSPH6 and DYNLRB1

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		MPHOSPH6	DYNLRB1
Gene Name		M-phase phosphoprotein 6	dynein, light chain, roadblock-type 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleolus Cytoplasm	Cytoplasm Centrosome Cytoplasmic Dynein Complex Microtubule Membrane Primary Cilium Ciliary Tip
	Molecular Function	RNA Binding Protein Binding	Microtubule Motor Activity
	Biological Process	Maturation Of 5.8S RRNA	Transport Organelle Organization Microtubule-based Movement Visual Behavior Metabolic Process
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		24 interactors: AATF APLP1 ARHGAP18 C14orf1 DNM2 DYNLRB1 EIF3G EXOSC10 FTL GDF9 KNSTRN LRIF1 NUPR1 PARN RBM48 RPS20 SKIV2L2 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1	6 interactors: CPEB1 DYNC1I1 DYNC1I2 HSPH1 MPHOSPH6 MPP6
Entrez ID		10200	83658
HPRD ID		16111	06203
Ensembl ID		ENSG00000135698	ENSG00000125971
Uniprot IDs		Q99547	B4DFR2 Q9NP97
PDB IDs			1Z09 2B95 2E8J 2HZ5
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Regulation Of Female Gonad Development Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Maturation Of 5.8S RRNA Positive Regulation Of Protein Oligomerization Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Endocytosis Regulation Of Protein Oligomerization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitotic Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Negative Regulation Of Cell Growth MRNA Catabolic Process Negative Regulation Of Fibroblast Proliferation Nitrogen Compound Metabolic Process Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Cell Division Regulation Of Gene Expression RNA Catabolic Process Ribosome Biogenesis Regulation Of Metabolic Process Mitotic Cytokinesis Negative Regulation Of Reactive Oxygen Species Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Membrane Organization Growth Negative Regulation Of Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Growth Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Processing Regulation Of Apoptotic Process Negative Regulation Of Macromitophagy Negative Regulation Of Membrane Tubulation Lipid Tube Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Negative Regulation Of Caveolin-mediated Endocytosis Oocyte Growth	Maturation Of 5.8S RRNA Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II RRNA Processing RRNA Metabolic Process Ribosome Biogenesis Positive Regulation Of NK T Cell Activation Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of Cytoplasmic Translation Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Microtubule-based Movement Regulation Of Cytoplasmic Translation Ribonucleoprotein Complex Biogenesis Regulation Of MHC Class I Biosynthetic Process Synaptonemal Complex Assembly NcRNA Metabolic Process Synaptonemal Complex Organization Chaperone Mediated Protein Folding Requiring Cofactor
Tagcloud ?			associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll2 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Difference) ?			associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll2 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Intersection) ?