MPHOSPH6 and NUPR1

Number of citations of the paper that reports this interaction (PMID 19650074)
6

Data Source:
BioGRID (two hybrid)

		MPHOSPH6	NUPR1
Gene Name		M-phase phosphoprotein 6	nuclear protein, transcriptional regulator, 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleolus Cytoplasm	Nucleus Cytoplasm
	Molecular Function	RNA Binding Protein Binding	Molecular_function DNA Binding Chromatin Binding
	Biological Process	Maturation Of 5.8S RRNA	Acute Inflammatory Response Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Protein Acetylation Male Gonad Development Response To Toxic Substance Cell Growth Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Negative Regulation Of Fibroblast Proliferation Regulation Of Female Gonad Development
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Inflammatory bowel disease ( 23128233) Inflammatory bowel disease (early onset) ( 19915574)
Protein-Protein Interactions		24 interactors: AATF APLP1 ARHGAP18 C14orf1 DNM2 DYNLRB1 EIF3G EXOSC10 FTL GDF9 KNSTRN LRIF1 NUPR1 PARN RBM48 RPS20 SKIV2L2 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1	21 interactors: ABCG8 ALDH1A1 EP300 FUS KNSTRN MAPRE1 MPHOSPH6 MSL1 NACA NONO NPY5R PAXIP1 PSMD4 PTMA RAN RANBP1 RPL41 SEC11A SET STX18 SYNCRIP
Entrez ID		10200	26471
HPRD ID		16111	17814
Ensembl ID		ENSG00000135698	ENSG00000176046
Uniprot IDs		Q99547	O60356
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Regulation Of Female Gonad Development Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Maturation Of 5.8S RRNA Positive Regulation Of Protein Oligomerization Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Endocytosis Regulation Of Protein Oligomerization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitotic Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Negative Regulation Of Cell Growth MRNA Catabolic Process Negative Regulation Of Fibroblast Proliferation Nitrogen Compound Metabolic Process Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Cell Division Regulation Of Gene Expression RNA Catabolic Process Ribosome Biogenesis Regulation Of Metabolic Process Mitotic Cytokinesis Negative Regulation Of Reactive Oxygen Species Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Membrane Organization Growth Negative Regulation Of Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Growth Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Processing Regulation Of Apoptotic Process Negative Regulation Of Macromitophagy Negative Regulation Of Membrane Tubulation Lipid Tube Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Negative Regulation Of Caveolin-mediated Endocytosis Oocyte Growth	Viral Process Gene Expression Positive Regulation Of Protein Binding Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Organelle Organization Cell Cycle Signal Transduction By P53 Class Mediator Nitrogen Compound Metabolic Process Positive Regulation Of Binding Spindle Organization Cell Cycle Process Mitotic Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Binding Regulation Of Microtubule-based Process Nucleobase-containing Compound Metabolic Process Organelle Organization Regulation Of Histone Acetylation RNA Metabolic Process Histone H4 Acetylation Protein Localization To Organelle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Apoptotic Process Histone H2B Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Histone H3-K36 Methylation Generation Of Ovulation Cycle Rhythm Negative Regulation Of Programmed Cell Death MRNA Metabolic Process Negative Regulation Of Cell Death Peptidyl-lysine Modification Regulation Of Binding Mitotic Cell Cycle Phase Transition Intracellular Transport Cell Cycle Phase Transition Chromosome Organization Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Cellular Process Rhythmic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Mitotic Nuclear Division Ribosomal Small Subunit Export From Nucleus Positive Regulation Of ER To Golgi Vesicle-mediated Transport N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Microtubule Plus-end Binding Endoplasmic Reticulum Membrane Organization Positive Regulation Of Skeletal Muscle Tissue Growth
Tagcloud ?			95d altered arrest atpase c3orf1 carcinoma ccng2 col3a1 concurrently depleted depletion ecm focal inner introducing justified lung microarray migration mitochondrial notably preliminary pten remarkably timmdc1 timp3 translocase upregulated viable
Tagcloud (Difference) ?			95d altered arrest atpase c3orf1 carcinoma ccng2 col3a1 concurrently depleted depletion ecm focal inner introducing justified lung microarray migration mitochondrial notably preliminary pten remarkably timmdc1 timp3 translocase upregulated viable
Tagcloud (Intersection) ?