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MBD3 and CEP76
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, two hybrid)
MBD3
CEP76
Description
methyl-CpG binding domain protein 3
centrosomal protein 76
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
NuRD Complex
Protein-containing Complex
Cytoplasm
Centrosome
Centriole
Cytosol
Cytoskeleton
Protein-containing Complex
Molecular Function
DNA Binding
Protein Binding
Methyl-CpG Binding
Nucleosomal DNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Ventricular Cardiac Muscle Tissue Development
Chromatin Remodeling
DNA Methylation-dependent Constitutive Heterochromatin Formation
Tissue Development
Response To Nutrient Levels
Response To Estradiol
Epigenetic Regulation Of Gene Expression
Regulation Of Cell Fate Specification
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Embryonic Organ Development
Response To Bisphenol A
Regulation Of Stem Cell Differentiation
Regulation Of Centriole Replication
Pathways
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Regulation of endogenous retroelements by KRAB-ZFP proteins
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes
73 interacting genes:
AGR2
ANKRD33
ASCL4
ATF7
AURKA
CCDC183
CCHCR1
CCNC
CENPP
CEP70
CEP76
CT55
ERCC6
EXOC4
FAM136A
GADD45GIP1
GATAD2A
GATAD2B
GOLGA2
GOLGA6L9
H3-4
HDAC1
ICA1
IGFBP6
IK
JUN
KDM1A
KDM5B
KRT15
KRT16
LDOC1
LMO3
MAGEA2
MAGEA2B
MBD2
MBD3L1
MECOM
MEIS3
MEOX1
MEOX2
MIPOL1
MKRN3
MTA2
MTUS2
MYOG
NUTM1
PBX4
PDGFA
PFDN6
PICK1
PKNOX2
PRKAR1B
RAB3IP
RBBP4
RBBP7
RCN3
REL
RINT1
SDCBP
SERTAD3
SPEN
STMN2
SYCE1
TBC1D19
TET1
TIMM10B
TNNI1
TRIM54
TTC23
USP11
ZBTB7A
ZNF277
ZNF655
105 interacting genes:
AKAP7
AKT1
ANKRD36
ASH2L
BANP
C22orf39
CABP5
CACNB3
CAPN3
CAVIN3
CCDC92
CCNK
CDK18
CENPI
CIRSR
COIL
CRYBA4
CSNK1G1
CUTC
CWF19L2
DCTD
DDX6
DEAF1
DMTN
DVL3
DZIP1L
EAF1
EIF1AD
EP400P1
ERCC3
FAM90A1
GDAP2
GFAP
GORASP2
HACL2
HSF2
HSPB7
IQUB
KDM1A
KDM4D
KIAA1143
KIFBP
KLHDC4
L3MBTL2
LATS1
LNX1
MAGEA11
MBD3
MFAP1
MISP
MLH1
MYOZ1
NEK6
NFYC
NHLRC2
NME5
PAICS
PARD6B
PATZ1
PDGFRB
PDRG1
PDZD4
PDZD7
PIN1
PKP1
PLA2G6
PLCB1
POM121
RADIL
RALGPS1
RBM41
RIPPLY3
RNF128
RPL9
SALL2
SCNM1
SH2D4A
SINHCAF
SMG9
SPG21
STK26
SUOX
TBC1D27P
TCEA2
TCEANC
TCF19
TFAP2D
THRA
TOB2
TSPOAP1
TSSC4
TTC21A
TTLL10
TUFT1
TXNDC9
VEZF1
WDFY3
YY1
ZBTB24
ZBTB4
ZMAT2
ZNF185
ZNF653
ZNF76
ZNF85
Entrez ID
53615
79959
HPRD ID
04653
12694
Ensembl ID
ENSG00000071655
ENSG00000101624
Uniprot IDs
O95983
B4DP81
Q8TAP6
PDB IDs
2MB7
6CC8
6CCG
6CEU
6CEV
Enriched GO Terms of Interacting Partners
?
NuRD Complex
Chromatin Remodeling
Regulation Of Cell Fate Specification
Chromatin Organization
Regulation Of Transcription By RNA Polymerase II
Histone Deacetylase Complex
Regulation Of Cell Fate Commitment
Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Sequence-specific DNA Binding
Nucleosomal DNA Binding
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Metabolic Process
Regulation Of Stem Cell Differentiation
Sin3-type Complex
Regulation Of RNA Metabolic Process
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Stem Cell Population Maintenance
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Macromolecule Metabolic Process
Protein Binding
Chromosome
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Nucleobase-containing Compound Metabolic Process
Chromatin
Chromosome, Telomeric Region
Positive Regulation Of Metabolic Process
DNA-binding Transcription Factor Binding
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
DNA Binding
Negative Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Primary Metabolic Process
Positive Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Membrane Curvature Sensor Activity
Negative Regulation Of Protein Acetylation
Epigenetic Regulation Of Gene Expression
Somite Specification
Protein Binding
Nucleus
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