HERC1

Gene Name		HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity ARF Guanyl-nucleotide Exchange Factor Activity Ligase Activity
	Biological Process	Transport Negative Regulation Of Autophagy Protein Ubiquitination Cerebellar Purkinje Cell Differentiation Neuron Projection Development Positive Regulation Of GTPase Activity Neuromuscular Process Controlling Balance
Pathways
Drugs
Diseases
GWAS		Iris characteristics ( 21835309)
Protein-protein Interactions		7 interactors: BAK1 EP300 LAPTM5 PKM RNF11 SOX9 UBE2D3
Entrez ID		8925
HPRD ID		06894
Ensembl ID		ENSG00000103657
Uniprot IDs		Q15751
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Endocrine Pancreas Development Programmed Cell Death Regulation Of DNA-templated Transcription In Response To Stress Cell Death Death Response To Abiotic Stimulus Cellular Response To Mechanical Stimulus Negative Regulation Of Gene Expression Histone H2B Acetylation Regulation Of Cell Proliferation Involved In Tissue Homeostasis Epithelial Cell Proliferation Involved In Prostatic Bud Elongation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Pancreas Development Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Type I Interferon Production Cellular Response To Oxygen Levels Primary Prostatic Bud Elongation Retinal Rod Cell Differentiation Fibroblast Apoptotic Process Camera-type Eye Morphogenesis Regulation Of Protein Binding Tube Development B Cell Negative Selection N-terminal Peptidyl-lysine Acetylation Renal Vesicle Induction Male Germ-line Sex Determination Response To Endoplasmic Reticulum Stress Eye Morphogenesis Positive Regulation Of Extracellular Matrix Assembly Metanephric Nephron Tubule Formation Intestinal Epithelial Structure Maintenance Intrahepatic Bile Duct Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Positive Regulation Of Mesenchymal Stem Cell Differentiation Primary Sex Determination Response To Mycotoxin Astrocyte Fate Commitment Post-embryonic Camera-type Eye Morphogenesis Negative Regulation Of Photoreceptor Cell Differentiation Limb Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Intrinsic Apoptotic Signaling Pathway Response To Transforming Growth Factor Beta Regulation Of Tubulin Deacetylation Regulation Of Extracellular Matrix Assembly Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Tagcloud ?		bcl11b cadherin discovered dnm2 druggable exhibitedthe fat1 fbxw7 frequencies guide harboured jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1 zrsr2