PIN4 and FAM9B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PIN4	FAM9B
Description		peptidylprolyl cis/trans isomerase, NIMA-interacting 4	family with sequence similarity 9 member B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Spindle Cytoskeleton Preribosome	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm
	Molecular Function	DNA Binding Bent DNA Binding Double-stranded DNA Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity	Protein Binding
	Biological Process	RRNA Processing	Spermatid Development Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder ( 34069769) Rosacea symptom severity ( 29771307)	Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)
Interacting Genes		19 interacting genes: ASCC2 CEBPA CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR ERBB2 ERBB3 ERBB4 EZH2 FAM9B FATE1 FBL FRMD1 MAGEA11 PNMA1 SPTAN1 ZBTB9	140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614
Entrez ID		5303	171483
HPRD ID		02219	15955
Ensembl ID		ENSG00000102309	ENSG00000177138
Uniprot IDs		Q9Y237	Q8IZU0
PDB IDs		1EQ3 1FJD 3UI4 3UI5 3UI6
Enriched GO Terms of Interacting Partners?		ERBB2 Signaling Pathway Basal Plasma Membrane Epidermal Growth Factor Receptor Signaling Pathway ERBB3:ERBB2 Complex ERBB Signaling Pathway Protein Kinase CK2 Complex Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Identical Protein Binding Gland Development Protein Tyrosine Kinase Activity ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Regeneration Protein Kinase Activity Cellular Response To Epidermal Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Animal Organ Regeneration Negative Regulation Of Apoptotic Process ERBB2-EGFR Signaling Pathway Negative Regulation Of Programmed Cell Death ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Kinase Activity Protein-containing Complex Localization Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Regulation Of Chromosome Separation Animal Organ Development Regulation Of Apoptotic Process Positive Regulation Of Protein Phosphorylation Regulation Of Programmed Cell Death Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of MAPK Cascade Protein Tyrosine Kinase Activator Activity Basolateral Plasma Membrane Positive Regulation Of Growth Positive Regulation Of Phosphorylation Positive Regulation Of Intracellular Signal Transduction Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein Metabolic Process Liver Development Positive Regulation Of Signal Transduction Regulation Of Cell Population Proliferation Positive Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Catabolic Process Embryonic Placenta Development	Protein Binding Mitochondrial Matrix RNA Binding
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