PIN4 and DNM1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PIN4	DNM1
Gene Name		protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)	dynamin 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Mitochondrial Matrix Spindle Preribosome Extracellular Vesicular Exosome	Microtubule Plasma Membrane Membrane Coat Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Bent DNA Binding Double-stranded DNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Poly(A) RNA Binding	GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding Protein Kinase Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding Nitric-oxide Synthase Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization RRNA Processing	Endocytosis Receptor-mediated Endocytosis Endosome Organization Axon Guidance Receptor Internalization Ephrin Receptor Signaling Pathway Clathrin-mediated Endocytosis
Pathways			Retrograde neurotrophin signalling Signalling by NGF Formation of annular gap junctions Axon guidance Gap junction degradation Gap junction trafficking L1CAM interactions NGF signalling via TRKA from the plasma membrane Recycling pathway of L1 Toll-Like Receptors Cascades EPH-ephrin mediated repulsion of cells Toll Like Receptor 4 (TLR4) Cascade Gap junction trafficking and regulation MHC class II antigen presentation EPH-Ephrin signaling Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		14 interactors: ASCC2 CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR EZH2 FAM9B FATE1 FBL MAGEA11 PNMA1 SPTAN1 ZBTB9	47 interactors: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GNB2L1 GRB2 GRIN1 GRIN2D ITSN1 KIAA1377 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP SH3GL1 SH3GL2 SH3GL3 SH3GLB1 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I
Entrez ID		5303	1759
HPRD ID		02219	03851
Ensembl ID		ENSG00000102309	ENSG00000106976
Uniprot IDs		Q9Y237	Q05193
PDB IDs		1EQ3 1FJD 3UI4 3UI5 3UI6	1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Negative Regulation Of Mitotic Cell Cycle Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Negative Regulation Of Protein Catabolic Process Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Mitotic Cell Cycle Generation Of Neurons Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Neurogenesis Neuron Development Cell Cycle Process Cell Morphogenesis Neuron Differentiation Cell Projection Organization Regulation Of Mitotic Cell Cycle Phase Transition Locomotion Regulation Of Cell Cycle Phase Transition Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Mitotic Cell Cycle Process Cell Cycle Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Cell Differentiation Nervous System Development Regulation Of Mitotic Metaphase/anaphase Transition Mitotic Cell Cycle Rhythmic Process Movement Of Cell Or Subcellular Component Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Alkanesulfonate Metabolic Process Histone Glutamine Methylation Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Cell Cycle Negative Regulation Of Cell Division Regulation Of Protein Catabolic Process Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Cell Development Response To External Stimulus	Endocytosis Vesicle-mediated Transport Regulation Of Cellular Component Organization Positive Regulation Of Protein Complex Assembly Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Cellular Component Assembly Neuron Projection Morphogenesis Positive Regulation Of Cellular Component Biogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Membrane Organization Transport Axon Guidance Cell Projection Organization Regulation Of Signaling Neuron Projection Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Protein Complex Assembly Vascular Endothelial Growth Factor Receptor Signaling Pathway Chemotaxis Synaptic Vesicle Transport Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Neuron Development Generation Of Neurons Membrane Tubulation Signaling Axonogenesis Anatomical Structure Development Protein Complex Assembly Neurogenesis Cell Communication Anatomical Structure Morphogenesis Locomotion Neurotrophin TRK Receptor Signaling Pathway Synaptic Vesicle Endocytosis Cell Morphogenesis Involved In Differentiation Axon Development Enzyme Linked Receptor Protein Signaling Pathway Synaptic Vesicle Recycling Regulation Of Signal Transduction Neurotrophin Signaling Pathway Regulation Of Phosphorylation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Positive Regulation Of Metabolic Process Neuron Differentiation Negative Regulation Of Endocytosis
Tagcloud ?		auxin compartments cues distinctive ectopically epidermis hl hydrophilic intercellular localizations localize modular natively pin1 pin2 pin5 pin7 pin8 pins plastic pm polar polarity subcellular switched thaliana trafficking transplanting	a432t a452v ankk1 arrb2 cdh13 chrna2 chrna9 dbh drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss
Tagcloud (Difference) ?		auxin compartments cues distinctive ectopically epidermis hl hydrophilic intercellular localizations localize modular natively pin1 pin2 pin5 pin7 pin8 pins plastic pm polar polarity subcellular switched thaliana trafficking transplanting	a432t a452v ankk1 arrb2 cdh13 chrna2 chrna9 dbh drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss
Tagcloud (Intersection) ?