PIN4 and MAGEA11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PIN4	MAGEA11
Description		peptidylprolyl cis/trans isomerase, NIMA-interacting 4	MAGE family member A11
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Spindle Cytoskeleton Preribosome	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	DNA Binding Bent DNA Binding Double-stranded DNA Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	RRNA Processing	Negative Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder ( 34069769) Rosacea symptom severity ( 29771307)
Interacting Genes		19 interacting genes: ASCC2 CEBPA CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR ERBB2 ERBB3 ERBB4 EZH2 FAM9B FATE1 FBL FRMD1 MAGEA11 PNMA1 SPTAN1 ZBTB9	115 interacting genes: ACMSD ACSM2B ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 BRD1 C18orf54 C22orf39 CASP7 CAVIN3 CCDC106 CCDC14 CCDC146 CCDC185 CCDC27 CCNA2 CDC20B CDKN2B CEP76 CLUAP1 CORO1A COX7A2L CSNK2A1 CTTNBP2 DLGAP1 DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A FAM161A FBXO46 GADD45GIP1 GCSH GNPDA1 HOXB5 IFI44 IL11 IL6ST ILF3 JADE3 KIAA0408 LMBR1L LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 NTAQ1 OTUB2 PCBD2 PCF11 PDE4B PHYH PIK3IP1 PIN4 PLCXD3 PNKD PNKP POLR1D PPIF PPM1K PRDX3 PRKRIP1 PSMF1 RADIL RANBP10 RBM23 REX1BD SH2D4A SNX20 SNX7 SPMIP9 STAR SUCLA2 SUOX SUV39H2 TCEA2 TCEANC TCF25 TEKTL1 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 UBE3D USP20 UTP25 VTA1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2
Entrez ID		5303	4110
HPRD ID		02219	02281
Ensembl ID		ENSG00000102309	ENSG00000185247
Uniprot IDs		Q9Y237	G5E962 P43364
PDB IDs		1EQ3 1FJD 3UI4 3UI5 3UI6	6WJH
Enriched GO Terms of Interacting Partners?		ERBB2 Signaling Pathway Basal Plasma Membrane Epidermal Growth Factor Receptor Signaling Pathway ERBB3:ERBB2 Complex ERBB Signaling Pathway Protein Kinase CK2 Complex Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Identical Protein Binding Gland Development Protein Tyrosine Kinase Activity ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Regeneration Protein Kinase Activity Cellular Response To Epidermal Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Animal Organ Regeneration Negative Regulation Of Apoptotic Process ERBB2-EGFR Signaling Pathway Negative Regulation Of Programmed Cell Death ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Kinase Activity Protein-containing Complex Localization Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Regulation Of Chromosome Separation Animal Organ Development Regulation Of Apoptotic Process Positive Regulation Of Protein Phosphorylation Regulation Of Programmed Cell Death Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of MAPK Cascade Protein Tyrosine Kinase Activator Activity Basolateral Plasma Membrane Positive Regulation Of Growth Positive Regulation Of Phosphorylation Positive Regulation Of Intracellular Signal Transduction Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein Metabolic Process Liver Development Positive Regulation Of Signal Transduction Regulation Of Cell Population Proliferation Positive Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Catabolic Process Embryonic Placenta Development	Mitochondrial Matrix Protein Binding Mitochondrion Catabolic Process
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