ATP6V1B1 and SLC9A3R1

Number of citations of the paper that reports this interaction (PMID 10748165)
31

Data Source:
HPRD (in vivo, in vitro)

		ATP6V1B1	SLC9A3R1
Gene Name		ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Microvillus Endomembrane System Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Extracellular Vesicular Exosome	Ruffle Nucleus Cytoplasm Centrosome Plasma Membrane Microvillus Endomembrane System Actin Cytoskeleton Membrane Apical Plasma Membrane Filopodium Brush Border Membrane Microvillus Membrane Vesicle Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Vesicular Exosome Cell Periphery Sperm Midpiece
	Molecular Function	ATP Binding Hydrogen Ion Transmembrane Transporter Activity Hydrolase Activity, Acting On Acid Anhydrides, Catalyzing Transmembrane Movement Of Substances Protein Complex Binding	Receptor Binding Protein Binding Beta-catenin Binding Chloride Channel Regulator Activity Phosphatase Binding PDZ Domain Binding Beta-2 Adrenergic Receptor Binding Protein Complex Binding Protein Complex Scaffold Protein Self-association Dopamine Receptor Binding Growth Factor Receptor Binding
	Biological Process	Ossification Cellular Iron Ion Homeostasis Regulation Of PH Excretion Sensory Perception Of Sound Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Proton Transport Transferrin Transport Inner Ear Morphogenesis PH Reduction ATP Metabolic Process Interaction With Host Calcium Ion Homeostasis Transmembrane Transport Phagosome Maturation	Renal Sodium Ion Transport Protein Complex Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Wnt Signaling Pathway Microvillus Assembly Actin Cytoskeleton Organization Negative Regulation Of Cell Migration Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium:proton Antiporter Activity Bile Acid Secretion Cellular Protein Localization Glutathione Transport Regulation Of Excretion Regulation Of Protein Kinase Activity Negative Regulation Of Protein Kinase B Signaling Phospholipase C-activating Dopamine Receptor Signaling Pathway Renal Absorption Negative Regulation Of ERK1 And ERK2 Cascade Renal Phosphate Ion Absorption Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS			Fibrinogen ( 20031577)
Protein-Protein Interactions		5 interactors: ACTN4 KDM1A SLC9A3R1 STX1A SUV39H1	52 interactors: ABCC2 ABCC4 ADRB2 AKAP10 ATP6V1B1 ATP6V1E1 BCL10 CFTR CLCN3 CNGA2 CTNNB1 EGFR EZR GNA11 GNAQ GRK6 KCNJ1 LHCGR LPAR2 MSN NF2 NOS2 OPRK1 P2RY1 PAG1 PDGFRA PDGFRB PDZK1 PIK3CA PLCB1 PLCB2 PTEN PTH1R RDX RLBP1 SCN4A SLC22A11 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC4A8 SLC9A3 SLCO1A2 SLCO3A1 TBC1D10A TRPC4 TRPC5 YAP1 YES1 ZNF468
Entrez ID		525	9368
HPRD ID		01887	05406
Ensembl ID		ENSG00000116039	ENSG00000109062
Uniprot IDs		P15313	O14745
PDB IDs			1G9O 1GQ4 1GQ5 1I92 1SGH 2D10 2JXO 2KJD 2KRG 2M0T 2M0U 2M0V 2OZF
Enriched GO Terms of Interacting Partners?		Regulation Of Sodium:proton Antiporter Activity Regulation Of Proton Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transport Organelle Organization Acid Secretion Regulation Of Sodium Ion Transport Secretion Renal Phosphate Ion Absorption Regulation Of Primitive Erythrocyte Differentiation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Localization To Tight Junction Positive Regulation Of Pinocytosis Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Cellular Component Movement Response To Abiotic Stimulus Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Histone H3-K9 Dimethylation Negative Regulation Of Sodium Ion Transmembrane Transport Response To Hypoxia Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Protein Localization To Cell Junction Histone H3-K4 Demethylation Carboxylic Acid Transport Organic Acid Transport Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Phospholipase C-activating Dopamine Receptor Signaling Pathway Exocytosis Positive Regulation Of Megakaryocyte Differentiation Bile Acid Secretion Regulation Of Apoptotic Process Synaptic Vesicle Fusion To Presynaptic Membrane Histone H3-K9 Trimethylation Regulation Of Vesicle-mediated Transport Positive Regulation Of Hormone Biosynthetic Process Peptidyl-lysine Dimethylation Oligopeptide Transport Regulation Of Cell Death Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Sodium Ion Transport Renal Absorption	Ion Homeostasis Ion Transmembrane Transport Transmembrane Transport Homeostatic Process Ion Transport Anion Transport Organic Anion Transport Anion Transmembrane Transport Chemical Homeostasis Cellular Ion Homeostasis Positive Regulation Of Phospholipase C Activity Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of PH Response To Organonitrogen Compound Cellular Chemical Homeostasis Monocarboxylic Acid Transport Positive Regulation Of Phospholipase Activity Transport Cellular Cation Homeostasis G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Vasodilation Regulation Of Phosphorus Metabolic Process Cellular Response To Organonitrogen Compound Response To Stimulus Inorganic Anion Transport Regulation Of Ion Transport Regulation Of Membrane Potential Cell Development Response To External Stimulus Monovalent Inorganic Cation Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Metal Ion Transport Cellular Homeostasis Establishment Of Endothelial Barrier Regulation Of Ion Transmembrane Transport Blood Coagulation Response To Estrogen Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Hemostasis Regulation Of Body Fluid Levels Signaling Wound Healing Response To Organic Substance Response To Hormone Cell Surface Receptor Signaling Pathway Cell Communication Cation Transport Positive Regulation Of Inositol Phosphate Biosynthetic Process
Tagcloud ?			adipogenic alters amscs chondrogenic commitment deacetylases destabilizes foxo1 grown hdac hdac1 hdac11 hydroxamic hyper interferes lysate manipulation mechanistically mesenchymal multipotency multipotent nherf1 osteogenic perturbation pluripotent saha sirt7 suberoylanilide uncommitted
Tagcloud (Difference) ?			adipogenic alters amscs chondrogenic commitment deacetylases destabilizes foxo1 grown hdac hdac1 hdac11 hydroxamic hyper interferes lysate manipulation mechanistically mesenchymal multipotency multipotent nherf1 osteogenic perturbation pluripotent saha sirt7 suberoylanilide uncommitted
Tagcloud (Intersection) ?