ATP6V1B1 and STX1A

Number of citations of the paper that reports this interaction (PMID 12651853)
5

Data Source:
BioGRID (pull down)

		ATP6V1B1	STX1A
Gene Name		ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	syntaxin 1A (brain)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Microvillus Endomembrane System Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Extracellular Vesicular Exosome	Extracellular Region Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Cell Junction Secretory Granule Synaptic Vesicle Membrane SNARE Complex Actomyosin Neuron Projection Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
	Molecular Function	ATP Binding Hydrogen Ion Transmembrane Transporter Activity Hydrolase Activity, Acting On Acid Anhydrides, Catalyzing Transmembrane Movement Of Substances Protein Complex Binding	SNARE Binding Glycoprotein Binding SNAP Receptor Activity Protein Binding Myosin Binding Calcium Channel Inhibitor Activity Chloride Channel Inhibitor Activity Kinase Binding Protein Domain Specific Binding Protein Binding, Bridging Myosin Head/neck Binding ATP-dependent Protein Binding Protein Heterodimerization Activity Protein N-terminus Binding Calcium-dependent Protein Binding
	Biological Process	Ossification Cellular Iron Ion Homeostasis Regulation Of PH Excretion Sensory Perception Of Sound Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Proton Transport Transferrin Transport Inner Ear Morphogenesis PH Reduction ATP Metabolic Process Interaction With Host Calcium Ion Homeostasis Transmembrane Transport Phagosome Maturation	Positive Regulation Of Neurotransmitter Secretion Energy Reserve Metabolic Process Intracellular Protein Transport Synaptic Transmission Neurotransmitter Secretion Pathogenesis Response To Gravity Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Calcium Ion-dependent Exocytosis Synaptic Vesicle Fusion To Presynaptic Membrane Secretion By Cell Cellular Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Exocytosis Vesicle Docking Regulation Of Insulin Secretion Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor	Dopamine Neurotransmitter Release Cycle Integration of energy metabolism Acetylcholine Neurotransmitter Release Cycle Regulation of insulin secretion Toxicity of botulinum toxin type C (BoNT/C) Norepinephrine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation Glutamate Neurotransmitter Release Cycle Peptide hormone metabolism Uptake and actions of bacterial toxins Neurotransmitter Release Cycle Insulin processing Serotonin Neurotransmitter Release Cycle Neurotoxicity of clostridium toxins Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ACTN4 KDM1A SLC9A3R1 STX1A SUV39H1	58 interactors: ABCC9 APBA1 ATP4B ATP6V1B1 CACNA1D CCSER2 CDK5 CFTR CPLX1 CSNK2A1 CSNK2A2 DAPK1 KCNB1 NAPA NAPB NSF PSMA3 RAB27A RIMS1 SCNN1A SCNN1B SCNN1G SDCBP SEPT2 SEPT5 SLC6A1 SLC6A2 SLC6A3 SLC6A4 SLC6A5 SLC6A9 SNAP23 SNAP25 SNAP29 SNPH STX8 STXBP1 STXBP2 STXBP5 STXBP6 SUMO1P1 SYT1 SYT4 SYT7 SYTL4 TRDMT1 TXLNA TXLNB UNC13B VAMP1 VAMP2 VAMP5 VAMP7 VAMP8 VAPB VIM VPS11 VPS18
Entrez ID		525	6804
HPRD ID		01887	01721
Ensembl ID		ENSG00000116039	ENSG00000106089
Uniprot IDs		P15313	A8MZ54 Q16623 Q75ME0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Sodium:proton Antiporter Activity Regulation Of Proton Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transport Organelle Organization Acid Secretion Regulation Of Sodium Ion Transport Secretion Renal Phosphate Ion Absorption Regulation Of Primitive Erythrocyte Differentiation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Localization To Tight Junction Positive Regulation Of Pinocytosis Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Cellular Component Movement Response To Abiotic Stimulus Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Histone H3-K9 Dimethylation Negative Regulation Of Sodium Ion Transmembrane Transport Response To Hypoxia Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Protein Localization To Cell Junction Histone H3-K4 Demethylation Carboxylic Acid Transport Organic Acid Transport Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Phospholipase C-activating Dopamine Receptor Signaling Pathway Exocytosis Positive Regulation Of Megakaryocyte Differentiation Bile Acid Secretion Regulation Of Apoptotic Process Synaptic Vesicle Fusion To Presynaptic Membrane Histone H3-K9 Trimethylation Regulation Of Vesicle-mediated Transport Positive Regulation Of Hormone Biosynthetic Process Peptidyl-lysine Dimethylation Oligopeptide Transport Regulation Of Cell Death Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Sodium Ion Transport Renal Absorption	Exocytosis Secretion By Cell Neurotransmitter Transport Secretion Regulation Of Exocytosis Regulation Of Neurotransmitter Levels Transport Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Transmission Cell-cell Signaling Regulation Of Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Cellular Localization Positive Regulation Of Exocytosis Regulation Of Cellular Localization Membrane Fusion Glutamate Secretion Establishment Of Vesicle Localization Vesicle Localization Ion Transport Vesicle Fusion Protein Transport Establishment Of Protein Localization Amino Acid Transport Vesicle Docking Organelle Fusion Membrane Docking Establishment Of Organelle Localization Membrane Organization Acid Secretion Vesicle Organization Positive Regulation Of Secretion Organelle Localization Protein Localization Monovalent Inorganic Cation Transport Anion Transport Dicarboxylic Acid Transport Regulated Secretory Pathway Metal Ion Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transport Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Sodium Ion Transport Organic Anion Transport
Tagcloud ?			colitis colonized died h7 hemolytic hemorrhagic hus isogenic k3995 lysogenic o157 outbreak outbreaks phage phages rabbits reflects shiga spinach stec streptomycin stx2 stx2a stx2c succumbed toxin uremic virulence
Tagcloud (Difference) ?			colitis colonized died h7 hemolytic hemorrhagic hus isogenic k3995 lysogenic o157 outbreak outbreaks phage phages rabbits reflects shiga spinach stec streptomycin stx2 stx2a stx2c succumbed toxin uremic virulence
Tagcloud (Intersection) ?