CPTP and CD7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CPTP	CD7
Description		ceramide-1-phosphate transfer protein	CD7 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Outer Membrane Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Phospholipid Binding Lipid Binding Lipid Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Lipid Transport Negative Regulation Of Autophagy Negative Regulation Of Interleukin-1 Beta Production Ceramide Transport Glycolipid Transport Intermembrane Lipid Transfer Negative Regulation Of NLRP3 Inflammasome Complex Assembly Ceramide 1-phosphate Transport	Adaptive Immune Response Immune System Process Positive Regulation Of T Cell Cytokine Production Immune Response Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Interleukin-2-mediated Signaling Pathway T Cell Activation
Pathways		Glycosphingolipid transport
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		7 interacting genes: CD7 ECM1 ELOC INPP5K PHF13 SMAD3 ZNF451	9 interacting genes: CPTP CTSL LGALS1 NFKBIA PI4KA PIK3R1 SEC22A SECTM1 SNAP29
Entrez ID		80772	924
HPRD ID		18878	01732
Ensembl ID		ENSG00000224051	ENSG00000173762
Uniprot IDs		Q5TA50 S4S694	P09564 Q29VG3
PDB IDs		4K80 4K84 4K85 4K8N 4KBS 4KF6
Enriched GO Terms of Interacting Partners?		Regulation Of Bone Mineralization Negative Regulation Of Ossification Transcription Corepressor Binding Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Renal Water Transport Phosphatidylinositol Trisphosphate Phosphatase Activity Positive Regulation Of Multicellular Organismal Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Ossification Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Interleukin-2 Receptor Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Sterol Response Element Binding Carbohydrate Homeostasis Transdifferentiation Glucose Homeostasis Positive Regulation Of Transforming Growth Factor Beta3 Production SMAD Protein Complex Pericardium Development DEAD/H-box RNA Helicase Binding Regulation Of Lung Blood Pressure Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Paraxial Mesoderm Morphogenesis Mesoderm Morphogenesis Heteromeric SMAD Protein Complex Regulation Of Stress Fiber Assembly Trophoblast Cell Migration Immune System Development Regulation Of Transforming Growth Factor Beta2 Production Target-directed MiRNA Degradation Elongin Complex Negative Regulation Of Transcription Initiation By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Initiation Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Bisphosphate Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity Negative Regulation Of Dephosphorylation Phosphatidylinositol Phosphate 5-phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Vasopressin Receptor Activity Negative Regulation Of Protein Targeting To Membrane Interleukin-2-mediated Signaling Pathway Regulation Of Immune Response	Membrane Organization Serpin Family Protein Binding Fusion Of Virus Membrane With Host Endosome Membrane Plasma Membrane Membrane Fusion Lactose Binding Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Cytokine Production Regulation Of Protein Import Into Nucleus Phosphatidylinositol Phosphate Biosynthetic Process Reorganization Of Cellular Membranes To Establish Viral Sites Of Replication SNAP Receptor Activity Macrophage Apoptotic Process Elastin Catabolic Process Fusion Of Virus Membrane With Host Plasma Membrane Immune System Process Chromaffin Granule Enkephalin Processing B Cell Differentiation Regulation Of Immune Response Positive Regulation Of Immune System Process Galectin Complex Receptor Ligand Activity Negative Regulation Of Hemopoiesis Lymphocyte Activation Involved In Immune Response Regulation Of Hemopoiesis Negative Regulation Of Multicellular Organismal Process Cytokine-mediated Signaling Pathway Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Transport Protein Import Into Nucleus I-kappaB/NF-kappaB Complex Negative Regulation Of Myeloid Cell Differentiation Kinase Regulator Activity Perinuclear Endoplasmic Reticulum Membrane Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process 1-phosphatidylinositol 4-kinase Activity Ciliary Pocket Membrane Elastin Metabolic Process Endolysosome Lumen Inflammatory Cell Apoptotic Process Leukocyte Activation Involved In Immune Response Positive Regulation Of Dendritic Cell Differentiation Cell Activation Involved In Immune Response Plasma Cell Differentiation Regulation Of Intracellular Protein Transport Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Establishment Of Protein Localization
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