CPTP and TCEB1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CPTP	TCEB1
Gene Name		ceramide-1-phosphate transfer protein	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
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Gene Ontology Annotations	Cellular Component	Nuclear Outer Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane	Nucleoplasm Cytosol VCB Complex Elongin Complex
	Molecular Function	Phospholipid Binding Phospholipid Transporter Activity Glycolipid Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transporter Activity	Protein Binding Protein Complex Binding
	Biological Process	Glycolipid Transport Ceramide 1-phosphate Transport	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Gene Expression Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia
Pathways			Vif-mediated degradation of APOBEC3G Formation of HIV-1 elongation complex containing HIV-1 Tat Cellular response to hypoxia RNA Polymerase II Transcription Regulation of Hypoxia-inducible Factor (HIF) by oxygen Antigen processing: Ubiquitination & Proteasome degradation Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events HIV elongation arrest and recovery HIV Life Cycle HIV Transcription Elongation Class I MHC mediated antigen processing & presentation Host Interactions of HIV factors Pausing and recovery of Tat-mediated HIV elongation Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription of the HIV genome Adaptive Immune System RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 20732625)
Protein-Protein Interactions		7 interactors: CD7 ECM1 INPP5K PHF13 SMAD3 TCEB1 ZNF451	34 interactors: ASB6 CBX5 CENPC COMMD1 CPTP CUL2 CUL3 CUL5 CYP2J2 ECT2 EFNB3 GNB2L1 JTB LRRC41 MCM7 MED8 METTL21C MRAS NOTCH4 PRAME RCAN2 RNF7 SAT2 SERTAD1 SOCS1 SOCS3 SOCS6 TCEB2 TCEB3B TCEB3C USP33 VHL WNT7B ZYG11B
Entrez ID		80772	6921
HPRD ID		18878	02875
Ensembl ID		ENSG00000224051	ENSG00000154582
Uniprot IDs		Q5TA50 S4S694	Q15369
PDB IDs		4K80 4K84 4K85 4K8N 4KBS 4KF6	1LM8 1LQB 1VCB 2C9W 2IZV 3DCG 3ZKJ 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K
Enriched GO Terms of Interacting Partners?		Regulation Of Stress Fiber Assembly Regulation Of Bone Mineralization Regulation Of Viral Transcription Negative Regulation Of Ossification Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Renal Water Transport Regulation Of Dephosphorylation Negative Regulation Of Glycogen (starch) Synthase Activity Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Viral Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Ossification Regulation Of Extracellular Matrix Assembly Negative Regulation Of Protein Metabolic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Protein Targeting To Membrane Primary MiRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Negative Regulation Of Glycogen Biosynthetic Process Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Osteoblast Proliferation Regulation Of Glycogen (starch) Synthase Activity SMAD Protein Complex Assembly Regulation Of Intracellular Protein Transport Regulation Of Transforming Growth Factor Beta2 Production Transdifferentiation T Cell Aggregation T Cell Activation Ossification Lymphocyte Aggregation Negative Regulation Of Signal Transduction Regulation Of Transcription, DNA-templated Leukocyte Aggregation Regulation Of Epithelial Cell Proliferation Positive Regulation Of Catenin Import Into Nucleus Regulation Of Nucleic Acid-templated Transcription Response To Hypoxia Regulation Of RNA Biosynthetic Process Negative Regulation By Host Of Viral Transcription Positive Regulation Of Alkaline Phosphatase Activity Negative Regulation Of Stress Fiber Assembly Regulation Of RNA Metabolic Process Inositol Phosphate Dephosphorylation Negative Regulation Of Protein Phosphorylation Leukocyte Cell-cell Adhesion Negative Regulation Of Signaling Positive Regulation Of Urine Volume Phosphorylated Carbohydrate Dephosphorylation	Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Intracellular Signal Transduction Negative Regulation Of JAK-STAT Cascade Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Programmed Cell Death Regulation Of Phosphorylation Cellular Protein Modification Process Cell Death Death Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transferase Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cell Cycle JAK-STAT Cascade Cell Cycle Process Cellular Protein Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Protein Phosphorylation G1/S Transition Of Mitotic Cell Cycle Response To Stress Viral Process Regulation Of Protein Metabolic Process Apoptotic Signaling Pathway Regulation Of Metabolic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Regulation Of JAK-STAT Cascade Mitotic Cell Cycle Process Protein Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Regulation Of Interferon-gamma-mediated Signaling Pathway Cell Cycle Phase Transition Cell Morphogenesis Labyrinthine Layer Morphogenesis JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Tagcloud ?			adrenal arise bc chromaffin cnl copy cul2 disrupting elongin enrichment harbored heterozygosity hif1 hif1a hippel hypoxic indeed inherited lindau merit normoxic pcc pheochromocytomas predisposing pseudohypoxic rbx1 tceb2 vhl von
Tagcloud (Difference) ?			adrenal arise bc chromaffin cnl copy cul2 disrupting elongin enrichment harbored heterozygosity hif1 hif1a hippel hypoxic indeed inherited lindau merit normoxic pcc pheochromocytomas predisposing pseudohypoxic rbx1 tceb2 vhl von
Tagcloud (Intersection) ?