PJA2

Gene Name		praja ring finger 2, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Postsynaptic Density Cell Junction Postsynaptic Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Protein Kinase A Catalytic Subunit Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Long-term Memory Regulation Of Protein Kinase A Signaling Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		12 interactors: MAGED1 PRKAR1A PRKAR2A UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2J1 UBE2L6 UBE2N UBE2W
Entrez ID		9867
HPRD ID		11436
Ensembl ID		ENSG00000198961
Uniprot IDs		O43164
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Innate Immune Response Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Protein K48-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Innate Immune Response Cellular Response To Organic Substance TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune Response Defense Response Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Cellular Response To Hypoxia Positive Regulation Of Transferase Activity Cellular Response To Decreased Oxygen Levels Protein K11-linked Ubiquitination Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Oxygen Levels Response To Organic Substance Catabolic Process Negative Regulation Of Type I Interferon Production Immune System Process Immune Response-regulating Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Protein Modification Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Response To Stress Negative Regulation Of CAMP-dependent Protein Kinase Activity Positive Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?		akap akap149 akaps camp complementary crc dependence destabilization e3 enzymatic exploiting fate generates igf1r ligase manipulation mechanistic opposing opposite organized osi pka praja2 respect subset survivin tgfbeta utilize xiap