KCNK9 and YWHAH

Number of citations of the paper that reports this interaction (PMID 12433946)
25

Data Source:
HPRD (in vivo, two hybrid)

		KCNK9	YWHAH
Gene Name		potassium channel, two pore domain subfamily K, member 9	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Integral Component Of Membrane	Cytoplasm Cytosol Plasma Membrane Intercalated Disc Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Protein Homodimerization Activity Protein Heterodimerization Activity	Actin Binding Insulin-like Growth Factor Receptor Binding Protein Binding Sodium Channel Regulator Activity Enzyme Binding Protein Domain Specific Binding Glucocorticoid Receptor Binding Ion Channel Binding Protein Heterodimerization Activity
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport Cochlea Development	Regulation Of Sodium Ion Transport Glucocorticoid Catabolic Process Intracellular Protein Transport Apoptotic Process Substantia Nigra Development Glucocorticoid Receptor Signaling Pathway Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Regulation Of Synaptic Plasticity Negative Regulation Of Dendrite Morphogenesis Membrane Organization Membrane Depolarization During Action Potential Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		TWIK-releated acid-sensitive K+ channel (TASK) Tandem pore domain potassium channels Potassium Channels	Activation of BAD and translocation to mitochondria Programmed Cell Death Translocation of GLUT4 to the plasma membrane Activation of BH3-only proteins Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS		Adiponectin levels ( 21700879)
Protein-Protein Interactions		7 interactors: SFN YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	61 interactors: ABL1 ARHGEF28 BAD BCR BRAF CDC25B CDC25C CDK16 CDKN1B CHRNA4 CREBBP EPB41L2 EPB41L3 ESR1 ESR2 EXO1 GREM1 ING1 KCNH2 KCNK15 KCNK3 KCNK9 KIF5B KLC3 KRT18 MAP3K3 MAP3K5 MARK4 MDM4 MED1 MST1R NCOA1 NCOA2 NCOA3 NEK1 NR3C1 NRIP1 PARD3 PARD6A PARD6B PARK2 PDPK1 PRKCI PTH1R RAF1 REM1 RIMS1 RIMS2 RPH3A SAMSN1 SNCA SRC THRA TLX2 TNFAIP3 TPH1 TSC1 TSC2 YWHAE YWHAG ZFP36
Entrez ID		51305	7533
HPRD ID		16167	00215
Ensembl ID		ENSG00000169427	ENSG00000128245
Uniprot IDs		Q9NPC2	Q04917 Q9H4N8
PDB IDs		3P1N 3P1O 3P1P 3P1Q 3P1R 3P1S 3SMK 3SML 3SMM 3SMN 3SMO 3SPR 3UX0 4FR3	2C63 2C74
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Regulation Of Intracellular Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Regulation Of Protein Localization Membrane Organization Regulation Of Organelle Organization Apoptotic Process Programmed Cell Death Regulation Of Cellular Localization Cell Death Death Positive Regulation Of Signal Transduction Regulation Of Apoptotic Process Regulation Of Cell Death Intracellular Signal Transduction Intracellular Protein Transport Regulation Of Cellular Component Organization Protein Targeting Substantia Nigra Development Cellular Protein Localization Protein Transport Regulation Of Signal Transduction Establishment Of Protein Localization Neural Nucleus Development Intracellular Transport Regulation Of Signaling Negative Regulation Of Protein Dephosphorylation Midbrain Development Protein Localization Establishment Of Localization In Cell Cellular Localization Signal Transduction Hippo Signaling Negative Regulation Of Cellular Protein Metabolic Process Signaling Cell Communication Negative Regulation Of Protein Metabolic Process	Signaling Cell Communication Regulation Of Kinase Activity Anatomical Structure Development Developmental Process Cellular Response To Organic Substance Positive Regulation Of Metabolic Process Signal Transduction Regulation Of Phosphorus Metabolic Process System Development Multicellular Organismal Development Regulation Of Protein Phosphorylation Cellular Response To Stimulus Regulation Of Cell Death Regulation Of Protein Kinase Activity Regulation Of Cellular Process Response To Organic Substance Regulation Of Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Cellular Metabolic Process Regulation Of Signaling Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of Apoptotic Process Intracellular Steroid Hormone Receptor Signaling Pathway Response To Hormone Cellular Response To Hormone Stimulus Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Intracellular Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Component Organization Regulation Of Catalytic Activity Anatomical Structure Morphogenesis Regulation Of Cell Proliferation Regulation Of Metabolic Process Negative Regulation Of Protein Phosphorylation Organelle Organization Cell Cycle Negative Regulation Of Cellular Metabolic Process Response To Organonitrogen Compound Apoptotic Process Cellular Response To Growth Factor Stimulus Positive Regulation Of Programmed Cell Death Programmed Cell Death Response To Growth Factor
Tagcloud ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnd2 kcnj3 kcnj6 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant	3eta 3gamma accumulates add bipolar clumped deformed deionized eggs localizes maturation matured meiosis meiotic metaphase microinjected microtubules morpholino oligonucleotide oocyte oocytes proximity reproduction spindle spindles tubulin uninjected visualization
Tagcloud (Difference) ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnd2 kcnj3 kcnj6 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant	3eta 3gamma accumulates add bipolar clumped deformed deionized eggs localizes maturation matured meiosis meiotic metaphase microinjected microtubules morpholino oligonucleotide oocyte oocytes proximity reproduction spindle spindles tubulin uninjected visualization
Tagcloud (Intersection) ?