KCNK9

Description		potassium two pore domain channel subfamily K member 9
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Synaptic Vesicle Membrane Dendrite Cell Projection
	Molecular Function	Voltage-gated Potassium Channel Activity Potassium Channel Activity Sodium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Potassium Ion Leak Channel Activity Identical Protein Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Visual Perception Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Regulation Of Resting Membrane Potential Cellular Response To Acidic PH Potassium Ion Transmembrane Transport Regulation Of Action Potential Firing Rate Potassium Ion Import Across Plasma Membrane Negative Regulation Of Aldosterone Secretion
Pathways		TWIK-releated acid-sensitive K+ channel (TASK) Phase 4 - resting membrane potential
Drugs		Doxapram Halothane
Diseases		Birk Barel mental retardation syndrome (BBMRS); Birk-Barel syndrome (BIBAS)
GWAS		Adiponectin levels ( 21700879) Cerebrospinal fluid t-tau:AB1-42 ratio ( 26252872) Cerebrospinal T-tau levels ( 26252872) Circulating phylloquinone levels ( 25411281) Low density lipoprotein cholesterol levels ( 30498476) Menarche (age at onset) ( 25231870) Response to lurasidone in schizophrenia ( 29730043) Urate levels in overweight individuals ( 25811787) Visceral adipose tissue ( 26480920)
Interacting Genes		7 interacting genes: SFN YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		51305
HPRD ID		16167
Ensembl ID		ENSG00000169427
Uniprot IDs		Q9NPC2
PDB IDs		3P1N 3P1O 3P1P 3P1Q 3P1R 3P1S 3SMK 3SML 3SMM 3SMN 3SMO 3SP5 3SPR 3UX0 4FR3 6GHP 8K1J 8K1Q 8K1V 8K1Z 9G9V 9G9W
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Protein Sequestering Activity Protein Domain Specific Binding Protein Targeting Establishment Of Protein Localization Intracellular Protein Localization Identical Protein Binding Transmembrane Transporter Binding Focal Adhesion Extracellular Exosome Phosphoprotein Binding Protein Kinase C Inhibitor Activity Substantia Nigra Development Neural Nucleus Development Cadherin Binding Melanosome Intracellular Signal Transduction Regulation Of Protein Localization Regulation Of Nucleocytoplasmic Transport Insulin-like Growth Factor Receptor Binding Regulation Of Intracellular Protein Transport Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Immune System Process Signal Transduction Negative Regulation Of Immune Response Negative Regulation Of Protein Localization Regulation Of Protein Export From Nucleus Regulation Of Transport Regulation Of Intracellular Transport Protein Phosphatase Inhibitor Activity Negative Regulation Of Protein Localization To Nucleus Cellular Response To Glucose Starvation Intracellular Signaling Cassette Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Immune Response Cytosol TORC1 Signaling Negative Regulation Of TORC1 Signaling Negative Regulation Of Protein Kinase Activity Negative Regulation Of Monoatomic Ion Transmembrane Transport Enzyme Binding Glucocorticoid Catabolic Process Negative Regulation Of Kinase Activity Regulation Of Monoatomic Ion Transport Negative Regulation Of Transport TOR Signaling Regulation Of Protein Transport Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Innate Immune Response Positive Regulation Of Intracellular Protein Transport
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