ZNF219 and SH3KBP1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZNF219	SH3KBP1
Gene Name		zinc finger protein 219	SH3-domain kinase binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Integral Component Of Membrane	Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Focal Adhesion Cytoplasmic Vesicle Membrane Neuron Projection Synapse
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Histamine Receptor Activity Protein Binding Metal Ion Binding	Protein Binding SH3 Domain Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Neurotransmitter Levels Transcription, DNA-templated Regulation Of Transcription, DNA-templated G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated	Endocytosis Apoptotic Process Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway Cell-cell Signaling Regulation Of Cell Shape Cell Migration Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Pathways			Signaling by the B Cell Receptor (BCR) Signaling by EGFR EGFR downregulation Signaling by EGFR in Cancer Signaling by Ligand-Responsive EGFR Variants in Cancer Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by EGFRvIII in Cancer Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: BCL2L1 CDK4 CSNK2A2 CTBP1 LMO1 MAPK3 MAPK8 SH3GL2 SH3KBP1 SUFU TTC32	45 interactors: ABI2 ARAP1 ARHGAP27 ASAP1 ASAP2 BCAR1 BLNK BMPR1B CAPZA1 CBL CBLB CD2 GRB2 HCK INPP5D ITSN2 LMNA MVB12A NEDD4 PAK2 PDCD6 PDCD6IP PIK3CA PIK3R1 PNMA5 PSMA3 SH3BP2 SH3GL2 SH3GL3 SH3GLB1 SH3GLB2 SHKBP1 SOS1 SPRY2 STAP1 SUMO1 SUMO2 SUMO3 SYNJ1 TAF6 TJP2 UBB UBC ZBTB7B ZNF219
Entrez ID		51222	30011
HPRD ID		05435	02301
Ensembl ID		ENSG00000165804	ENSG00000147010
Uniprot IDs		Q9P2Y4	B7Z6E8 Q5JPT6 Q96B97
PDB IDs			2BZ8 2K6D 2K9G 2O2O 2YDL
Enriched GO Terms of Interacting Partners?		Regulation Of Chromosome Organization Regulation Of Cellular Component Organization Regulation Of Histone Modification Regulation Of Organelle Organization Apoptotic Process Programmed Cell Death Cell Death Death Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Cellular Protein Metabolic Process Cell Surface Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Neurotrophin Signaling Pathway Protein Phosphorylation Regulation Of Histone Deacetylation Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signal Transduction Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Histone Acetylation Regulation Of Protein Deacetylation Negative Regulation Of Protein Binding Regulation Of Metabolic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Signaling Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Cell Part Morphogenesis TRIF-dependent Toll-like Receptor Signaling Pathway Cell Communication Regulation Of Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Cell Cycle MyD88-dependent Toll-like Receptor Signaling Pathway Cellular Response To Mechanical Stimulus Positive Regulation Of Histone Modification Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Apoptotic Process In Bone Marrow Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Negative Regulation Of Cellular Protein Catabolic Process	Regulation Of Signal Transduction Regulation Of Signaling Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Cellular Process Signaling Signal Transduction Cell Communication Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway T Cell Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Fibroblast Growth Factor Regulation Of Apoptotic Process Positive Regulation Of Signal Transduction Cell Surface Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Protein Catabolic Process Regulation Of Cell Death Antigen Receptor-mediated Signaling Pathway Neurotrophin Signaling Pathway Immune Response-regulating Signaling Pathway Apoptotic Process Immune System Process Programmed Cell Death Cellular Response To Stimulus Cell Death Death Fc Receptor Signaling Pathway Immune Response Viral Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Endocytosis Locomotion Movement Of Cell Or Subcellular Component Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Catalytic Activity Regulation Of Immune Response
Tagcloud ?			calm3 cblb ccna2 ccnd3 cdk6 cited1 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 shc tgfbr1 tgfbr2 vav2 wilcoxon yes zfyve9
Tagcloud (Difference) ?			calm3 cblb ccna2 ccnd3 cdk6 cited1 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 shc tgfbr1 tgfbr2 vav2 wilcoxon yes zfyve9
Tagcloud (Intersection) ?