NDUFA13 and HSPB2

Number of citations of the paper that reports this interaction (PubMedID 26465331)
76

Data Source:
BioGRID (two hybrid)

		NDUFA13	HSPB2
Description		NADH:ubiquinone oxidoreductase subunit A13	heat shock protein family B (small) member 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex I Respiratory Chain Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding ATP Binding Endopeptidase Activator Activity	Structural Constituent Of Eye Lens Protein Binding Enzyme Activator Activity Unfolded Protein Binding
	Biological Process	Apoptotic Process Aerobic Respiration Mitochondrial Respiratory Chain Complex I Assembly Cellular Response To Interferon-beta Proton Motive Force-driven Mitochondrial ATP Synthesis Protein Insertion Into Mitochondrial Inner Membrane Positive Regulation Of Protein Catabolic Process Negative Regulation Of DNA-templated Transcription Cellular Response To Retinoic Acid Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Execution Phase Of Apoptosis	Response To Unfolded Protein Somatic Muscle Development Response To Heat Protein Refolding Negative Regulation Of Apoptotic Process
Pathways		Respiratory electron transport Complex I biogenesis Mitochondrial protein degradation
Drugs		NADH
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Platelet count ( 27863252) Refractive error ( 32231278) Schizophrenia ( 23974872 25056061 29483656)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: EXOSC6 HSPB2 KRAS LIG4 STAT3 UBE3A XRN1	108 interacting genes: A1CF A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BAG3 BEX2 BEX4 BGN BICRAL C1QA CAPZA2 CEP19 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DMPK DUSP1 EEF1A1 EIF4A2 ENKD1 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HOXB9 HSPB3 HSPB8 KANK2 LGALS1 LMO1 LMO3 MAPKAPK5 MB MCCC2 MDH1 MISP MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PATZ1 PGM1 PKP2 POGZ PPM1K PRR35 RFPL3 RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 SNX18 TATDN1 TCAP THEMIS2 THUMPD2 TLX3 TNNI3 TTN TXNIP UBL5 VEZF1 WDR1 WWOX YPEL3 ZNF335
Entrez ID		51079	3316
HPRD ID		09452	03712
Ensembl ID		ENSG00000186010	ENSG00000170276
Uniprot IDs		Q9P0J0	A8KAH6 Q16082
PDB IDs		5XTB 5XTC 5XTD 5XTH 5XTI	6F2R
Enriched GO Terms of Interacting Partners?		Nuclear MRNA Surveillance RRNA Catabolic Process Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Somatic Diversification Of Immunoglobulins Involved In Immune Response Somatic Recombination Of Immunoglobulin Gene Segments Somatic Cell DNA Recombination Somatic Diversification Of Immunoglobulins RNA Surveillance Nuclear RNA Surveillance Response To Lipid B Cell Activation Involved In Immune Response Somatic Stem Cell Population Maintenance Establishment Of Integrated Proviral Latency Sperm Entry Positive Regulation Of Golgi Lumen Acidification Cellular Response To Puromycin Cellular Response To Cycloheximide Neuron Apoptotic Process GMP Binding Forebrain Astrocyte Development Modulation Of Chemical Synaptic Transmission DNA Ligase (ATP) Activity Stem Cell Population Maintenance DNA Ligase IV Complex Establishment Of Viral Latency Lymphocyte Activation Involved In Immune Response DNA Ligase Activity Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Regulation Of Golgi Lumen Acidification Nuclear-transcribed MRNA Catabolic Process Maintenance Of Cell Number Somatic Muscle Development Cytosol Response To Isolation Stress Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination DN2 Thymocyte Differentiation RNA Sequestering Activity 5'-3' RNA Exonuclease Activity MRNA Catabolic Process Positive Regulation Of Developmental Process Response To Hormone Leukocyte Activation Involved In Immune Response Cell Activation Involved In Immune Response Postsynapse To Nucleus Signaling Pathway MRNA Metabolic Process	Sarcomere Organization Sarcomere M Band Z Disc Striated Muscle Contraction Actomyosin Structure Organization Cardiac Muscle Tissue Morphogenesis Actin-mediated Cell Contraction Muscle Contraction ATP Metabolic Process Cardiac Muscle Contraction Generation Of Precursor Metabolites And Energy Skeletal Muscle Thin Filament Assembly Muscle Tissue Morphogenesis Actin Filament-based Process Actin-myosin Filament Sliding Muscle System Process Actin Filament-based Movement Cytoplasm Actin Cytoskeleton Organization I Band Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Cytoskeleton Organization Extracellular Exosome Actin Cytoskeleton Purine Ribonucleotide Metabolic Process Muscle Filament Sliding Nucleotide Metabolic Process Respiratory Electron Transport Chain Purine Nucleotide Metabolic Process Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Electron Transport Chain Cellular Respiration Mitochondrion Monocarboxylic Acid Metabolic Process Cardiac Myofibril Small Molecule Metabolic Process Purine-containing Compound Metabolic Process Ventricular Cardiac Muscle Tissue Morphogenesis Nucleoside Phosphate Metabolic Process Glycolytic Process Cardiac Muscle Hypertrophy ADP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process Tertiary Granule Lumen Purine Ribonucleoside Diphosphate Catabolic Process Response To Hypoxia Protein Refolding
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