EIF4ENIF1 and RPS7

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		EIF4ENIF1	RPS7
Description		eukaryotic translation initiation factor 4E nuclear import factor 1	ribosomal protein S7
Image
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Cytoplasmic Ribonucleoprotein Granule	Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Centrosome Cytosol Ribosome Cytoskeleton Focal Adhesion Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Small-subunit Processome Protein-containing Complex Synapse Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding Kinase Binding	RNA Binding MRNA 3'-UTR Binding Structural Constituent Of Ribosome Protein Binding Protein Kinase Binding MRNA 5'-UTR Binding Ubiquitin Ligase Inhibitor Activity
	Biological Process	Translation Regulation Of Translation Protein Import Into Nucleus Protein Transport Negative Regulation Of Translation Stem Cell Population Maintenance Neuron Differentiation Regulatory NcRNA-mediated Gene Silencing P-body Assembly MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Neuron Differentiation MRNA Stabilization Nuclear Export Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA	Neural Tube Closure Cytoplasmic Translation RRNA Processing Translation Positive Regulation Of Gene Expression Neural Crest Cell Differentiation Ribosomal Small Subunit Biogenesis Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases			Diamond-Blackfan anemia (DBA)
GWAS		Age-related hearing impairment ( 24939585) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		92 interacting genes: ALG13 ANKHD1 ANXA2 ATP5F1B ATXN1 BAG4 BCAS2 BYSL CDK6 CFAP206 CLASP1 CLK3 CPSF7 CTNNA1 CUL1 DAPK1 DDX1 DDX11 DDX28 DEF6 DHX37 DHX57 DST DTX2 EEF1G EFHC1 EHMT2 EIF3E EIF4E EIF4E2 ELAVL3 EXOSC7 FANCL FDPS FTSJ3 GOLGA4 HDGF HNRNPF HNRNPLL HOOK3 HSPA1A KPNA2 KRT19 KRT31 L3MBTL2 LLPH LMNA LUC7L MGAT5B MYO10 NOP9 NXF3 OIP5 PKP2 PNKP POLR2A PRR20A PRR20B PRR20C PRR20D PRR20E QKI RAE1 RBBP6 RBFOX2 RBM22 RNF10 RPL15 RPL19 RPL26 RPL31 RPRD1B RPS21 RPS6 RPS7 SF3B3 SMAD3 SNRNP40 SNRPN SPAG5 SRBD1 SRSF8 SUPV3L1 TCHP TRAK2 TTC19 TUBA1A TXLNA USP2 WBP4 WTAP XRCC6	12 interacting genes: CDKN2A DUX4 EIF4ENIF1 HOOK1 IPO5 IPO7 NEK6 OGT RPS4X TNPO1 UPF2 ZBTB14
Entrez ID		56478	6201
HPRD ID		10456	04712
Ensembl ID		ENSG00000184708	ENSG00000171863
Uniprot IDs		Q9NRA8	P62081
PDB IDs		5ANR 6F9W 6X2R	4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7MQ8 7MQ9 7MQA 7QP6 7QP7 7R4X 7TQL 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing MRNA Metabolic Process RNA Metabolic Process Nucleic Acid Metabolic Process Nucleic Acid Binding Nucleoplasm Macromolecule Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Regulation Of RNA Splicing Nucleus Nucleolus Cytosolic Ribosome Ribonucleoprotein Complex Cytoplasm Translation RNA Splicing Structural Constituent Of Ribosome RRNA Processing Nuclear Speck Cytoplasmic Translation Helicase Activity RRNA Metabolic Process Catalytic Step 2 Spliceosome Centrosome MRNA Splicing, Via Spliceosome Protein Binding RNA Splicing, Via Transesterification Reactions Macromolecule Biosynthetic Process Cytoskeleton Preribosome, Small Subunit Precursor Ribonucleoprotein Complex Biogenesis RNA Helicase Activity Prp19 Complex Spliceosomal Complex MRNA Binding Ribosome Positive Regulation Of RNA Splicing RNA 3'-end Processing Regulation Of Neurogenesis Microtubule Cytoskeleton Organization MRNA Cap Binding Ubiquitin Protein Ligase Binding Cytosolic Large Ribosomal Subunit Microtubule Plus-end Microtubule Anchoring Chromosome Cytosol Structural Molecule Activity	Protein Localization To Nucleus Nuclear Transport Nucleocytoplasmic Transport Protein Import Into Nucleus Import Into Nucleus Protein Localization To Organelle Nucleolus Cytoplasmic Ribonucleoprotein Granule Positive Regulation Of Protein Localization To Nucleus Negative Regulation Of Cell Cycle Cytosol Intracellular Protein Localization Nuclear Import Signal Receptor Activity Intracellular Transport Establishment Of Protein Localization To Organelle Nuclear Localization Sequence Binding Cytoplasm Regulation Of Protein Localization To Nucleus Nucleoplasm RNA Binding Cellular Localization Establishment Of Localization In Cell Intracellular Protein Transport Ligase Inhibitor Activity Nucleus Regulation Of Cell Cycle Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Lipid Localization Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Protein Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Membraneless Organelle Assembly Small GTPase Binding Negative Regulation Of Protein Ubiquitination Positive Regulation Of Gene Expression Autophagy Of Mitochondrion Stress-induced Mitochondrial Fusion Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization Nuclear Pore Negative Regulation Of Post-translational Protein Modification Translation Positive Regulation Of Macrophage Apoptotic Process Apoptotic Process Involved In Mammary Gland Involution Protein O-acetylglucosaminyltransferase Activity Negative Regulation Of Catabolic Process Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Senescence-associated Heterochromatin Focus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?