EIF4ENIF1 and FDPS

Number of citations of the paper that reports this interaction (PMID 19060904)
157

Data Source:
BioGRID (two hybrid)

		EIF4ENIF1	FDPS
Gene Name		eukaryotic translation initiation factor 4E nuclear import factor 1	farnesyl diphosphate synthase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Protein Transporter Activity Poly(A) RNA Binding	Dimethylallyltranstransferase Activity Geranyltranstransferase Activity Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Protein Transport	Cholesterol Biosynthetic Process Viral Process Geranyl Diphosphate Biosynthetic Process Small Molecule Metabolic Process Farnesyl Diphosphate Biosynthetic Process
Pathways			Regulation of cholesterol biosynthesis by SREBP (SREBF) Cholesterol biosynthesis Metabolism of lipids and lipoproteins Activation of gene expression by SREBF (SREBP)
Drugs			Pamidronate Zoledronate Alendronate Ibandronate Risedronate Dimethylallyl Diphosphate Isopentyl Pyrophosphate Geranyl Diphosphate ISOPENTENYL PYROPHOSPHATE FARNESYL DIPHOSPHATE GERANYLGERANYL DIPHOSPHATE
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ATXN1 CDK6 DDX6 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 MGAT5B OIP5 SMAD3 SPAG5 TTC19 TXLNA	3 interactors: ATXN1 EIF4ENIF1 FGFR1
Entrez ID		56478	2224
HPRD ID		10456	00606
Ensembl ID		ENSG00000184708	ENSG00000160752
Uniprot IDs		Q9NRA8	P14324
PDB IDs			1YQ7 1YV5 1ZW5 2F7M 2F89 2F8C 2F8Z 2F92 2F94 2F9K 2OPM 2OPN 2QIS 2RAH 2VF6 3B7L 3CP6 3N1V 3N1W 3N3L 3N45 3N46 3N49 3N5H 3N5J 3N6K 3RYE 3S4J 4DEM 4GA3 4H5C 4H5D 4H5E
Enriched GO Terms of Interacting Partners?		Cellular Macromolecular Complex Assembly Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Cell Division RNA Catabolic Process Posttranscriptional Regulation Of Gene Expression Cell Cycle Negative Regulation Of Osteoblast Differentiation Translational Initiation MRNA Metabolic Process Positive Regulation Of Cell-matrix Adhesion Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Viral Process Cell Dedifferentiation Positive Regulation Of Transforming Growth Factor Beta3 Production RNA Processing Regulation Of Translation Geranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Negative Regulation Of Ossification Mitotic Cell Cycle Process Negative Regulation Of Translation Evasion Or Tolerance Of Host Defenses By Virus Mitotic Cell Cycle Cellular Component Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Farnesyl Diphosphate Metabolic Process Regulation Of Cell-matrix Adhesion Lymphocyte Activation Positive Regulation Of Cell-substrate Adhesion Regulation Of Extracellular Matrix Assembly Nuclear Export	Regulation Of Lateral Mesodermal Cell Fate Specification Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Lung Development Respiratory Tube Development Ventricular Zone Neuroblast Division Respiratory System Development Orbitofrontal Cortex Development Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Outer Ear Morphogenesis Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling Mesenchymal-epithelial Cell Signaling Forebrain Neuroblast Division Regulation Of Branching Involved In Salivary Gland Morphogenesis Auditory Receptor Cell Development Lung-associated Mesenchyme Development Regulation Of Cell Fate Specification Tube Development Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Paraxial Mesoderm Development Middle Ear Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Somatic Stem Cell Division Positive Regulation Of Cardiac Muscle Cell Proliferation Branching Involved In Salivary Gland Morphogenesis Auditory Receptor Cell Differentiation Regulation Of Cell Fate Commitment Cell-cell Signaling Regulation Of Gastrulation Organ Induction Hair Cell Differentiation Positive Regulation Of Heart Growth Inner Ear Receptor Cell Development Positive Regulation Of Mesenchymal Cell Proliferation Stem Cell Division Regulation Of Cardiac Muscle Cell Proliferation Salivary Gland Morphogenesis Salivary Gland Development Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Organ Growth Cell Proliferation In Forebrain Negative Regulation Of Transcription, DNA-templated Developmental Induction Regulation Of Organ Formation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Lung Alveolus Development Neuroblast Proliferation Neurological System Process
Tagcloud ?			clopidogrel clots corresponds dissolution elt euglobulin extrinsic fgfc1 fibrin fibrinogen fibrinogenolysis fibrinolytic fitc fluorescein hemolytic hemorrhagic isothiocyanate lysis ogen olytic pharmacodynamic pyranoindole shortened stems thromboembolism thrombolysis thrombolytic thrombus urokinase
Tagcloud (Difference) ?			clopidogrel clots corresponds dissolution elt euglobulin extrinsic fgfc1 fibrin fibrinogen fibrinogenolysis fibrinolytic fitc fluorescein hemolytic hemorrhagic isothiocyanate lysis ogen olytic pharmacodynamic pyranoindole shortened stems thromboembolism thrombolysis thrombolytic thrombus urokinase
Tagcloud (Intersection) ?