EIF4ENIF1 and FANCL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EIF4ENIF1	FANCL
Gene Name		eukaryotic translation initiation factor 4E nuclear import factor 1	Fanconi anemia, complementation group L
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle	Nuclear Envelope Nucleoplasm Cytoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding Protein Transporter Activity Poly(A) RNA Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Transport	DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Regulation Of Cell Proliferation
Pathways			Fanconi Anemia pathway
Drugs
Diseases
GWAS			Body mass index ( 20935630) Obesity ( 23563607)
Protein-Protein Interactions		19 interactors: ATXN1 CDK6 DDX6 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 MGAT5B OIP5 SMAD3 SPAG5 TTC19 TXLNA	24 interactors: ACVR1 BMPR1B C17orf70 CCDC36 CHCHD3 DOCK8 EIF4ENIF1 FANCB FANCD2 FANCI GGN GRN HES1 IKZF3 KIFC3 LZTS2 PCNA RBM45 RIMBP3 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W
Entrez ID		56478	55120
HPRD ID		10456	06997
Ensembl ID		ENSG00000184708	ENSG00000115392
Uniprot IDs		Q9NRA8	B5MC31 B5MCZ6 Q9NW38
PDB IDs			3ZQS
Enriched GO Terms of Interacting Partners?		Cellular Macromolecular Complex Assembly Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Cell Division RNA Catabolic Process Posttranscriptional Regulation Of Gene Expression Cell Cycle Negative Regulation Of Osteoblast Differentiation Translational Initiation MRNA Metabolic Process Positive Regulation Of Cell-matrix Adhesion Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Viral Process Cell Dedifferentiation Positive Regulation Of Transforming Growth Factor Beta3 Production RNA Processing Regulation Of Translation Geranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Negative Regulation Of Ossification Mitotic Cell Cycle Process Negative Regulation Of Translation Evasion Or Tolerance Of Host Defenses By Virus Mitotic Cell Cycle Cellular Component Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Farnesyl Diphosphate Metabolic Process Regulation Of Cell-matrix Adhesion Lymphocyte Activation Positive Regulation Of Cell-substrate Adhesion Regulation Of Extracellular Matrix Assembly Nuclear Export	Pharyngeal System Development DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Single Organism Reproductive Process Pathway-restricted SMAD Protein Phosphorylation Response To Stress Reproductive Process Mesenchymal Cell Development Protein K11-linked Ubiquitination Epithelial Cell Fate Commitment Gamete Generation Mesenchymal Cell Differentiation Movement Of Cell Or Subcellular Component Activin Receptor Signaling Pathway Cellular Response To Stress Urogenital System Development Cellular Response To Stimulus Sexual Reproduction Multicellular Organismal Reproductive Process Positive Regulation Of Bone Mineralization Protein Monoubiquitination Positive Regulation Of Biomineral Tissue Development Multicellular Organism Reproduction Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Pattern Specification Process Mesenchyme Development Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-threonine Phosphorylation In Utero Embryonic Development Nucleobase-containing Compound Metabolic Process Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Positive Regulation Of Deoxyribonuclease Activity Pharyngeal Arch Artery Morphogenesis Memory T Cell Proliferation Lateral Inhibition Endocardial Cushion Cell Fate Commitment Cell Cycle Heart Morphogenesis Heart Development Smooth Muscle Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Artery Morphogenesis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cardiac Septum Morphogenesis Thymus Development Stem Cell Development Heterocycle Metabolic Process
Tagcloud ?			2p16 2q24 4p15 agencies assisting epilepsies epilepsy ethnically filtering generalised governmental grouping harbouring heritability ie implicating imputation league lumping pcdh7 phenotyped philanthropic pleiotropically protocadherin scn1a splitting standardised unclassified vrk2
Tagcloud (Difference) ?			2p16 2q24 4p15 agencies assisting epilepsies epilepsy ethnically filtering generalised governmental grouping harbouring heritability ie implicating imputation league lumping pcdh7 phenotyped philanthropic pleiotropically protocadherin scn1a splitting standardised unclassified vrk2
Tagcloud (Intersection) ?