BRSK1

Gene Name		BR serine/threonine kinase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Synaptic Vesicle Cell Junction
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity ATP Binding Protein Kinase Binding Gamma-tubulin Binding Tau-protein Kinase Activity
	Biological Process	Protein Phosphorylation Cellular Response To DNA Damage Stimulus Neurotransmitter Secretion Axonogenesis Response To UV Response To Ionizing Radiation Establishment Of Cell Polarity Neuron Differentiation G2 DNA Damage Checkpoint Centrosome Duplication
Pathways
Drugs
Diseases
GWAS		Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 19448619)
Protein-protein Interactions		8 interactors: BRCA1 CDC25B CDC25C HSD17B7 HSPA1A PAK1 UBC WEE1
Entrez ID		84446
HPRD ID		12533
Ensembl ID		ENSG00000160469
Uniprot IDs		Q8TDC3
PDB IDs
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Cell Cycle Process Regulation Of Cell Cycle Process Regulation Of Protein Metabolic Process Cell Cycle Regulation Of Protein Ubiquitination Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Process Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Kinase Activity Positive Regulation Of Cell Cycle Mitotic Nuclear Division Positive Regulation Of Protein Modification Process Cellular Protein Modification Process Protein Metabolic Process Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Cellular Protein Metabolic Process Cell Division DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation JNK Cascade Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Signal Transduction In Response To DNA Damage Positive Regulation Of Kinase Activity Regulation Of Cell Cycle Arrest Negative Regulation Of Protein Ubiquitination Regulation Of Phosphorylation T Cell Receptor Signaling Pathway Viral Process Signal Transduction By P53 Class Mediator Positive Regulation Of Transferase Activity Cellular Heat Acclimation Positive Regulation Of Histone H3-K9 Acetylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination
Tagcloud ?		aicar ampk ampkbeta blunted brsk2 c433s caax cys433 farnesylated farnesylation fertile imidazolecarboxamide knockin lkb1 lkb1c433s lkb1s431a mark4 mimetic myristoylation nuak nuak1 phenformin prenylated raises riboside s431a ser431 sik3 snf1