KRTAP12-4 and LCE1C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP12-4	LCE1C
Description		keratin associated protein 12-4	late cornified envelope 1C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Epidermis Development Keratinization
Pathways		Keratinization	Formation of the cornified envelope
Drugs
Diseases
GWAS			Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		51 interacting genes: AQP1 ARID5A ATXN1 ATXN2L CH25H CYSRT1 FBXO34 GPRIN2 HMGB4 HOXA1 IQUB KRTAP11-1 KRTAP12-2 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP6-2 KRTAP8-1 LASP1 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2C LCE3A LCE3D LCE4A LCE5A MEOX2 MGAT5B NBPF19 NOTCH2NLA NR4A3 OLIG2 OTX1 PIH1D2 POU4F2 RBPMS RERE SMCP SPMIP9 SSC4D TEKT5 TRIP13 VENTX	75 interacting genes: ADAMTSL4 ALPP CHIC2 CHRD CRCT1 CREB5 CYSRT1 EFEMP1 EFEMP2 FBLN1 GUCD1 HOXA1 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE4A LCE5A MACO1 NECTIN2 NTAQ1 NTN4 NUTF2 ODF1 OIT3 OTX1 PLA2G10 PLAC8 PLSCR3 PLSCR4 POU4F2 PSMB1 SLC39A7 SPRED2 SPRY1 SPRY2 TGFB1 TRIM42 VASN VWC2 VWC2L
Entrez ID		386684	353133
HPRD ID		11200	13967
Ensembl ID		ENSG00000212933	ENSG00000197084
Uniprot IDs		P60329	Q5T751
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development Intermediate Filament Tissue Development Identical Protein Binding Keratin Filament Protein Binding Sequence-specific DNA Binding Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Negative Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding Protein Binding Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Branch Elongation Of An Epithelium Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Epithelial To Mesenchymal Transition Axis Elongation Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Elastic Fiber Negative Regulation Of Cellular Response To Growth Factor Stimulus Extracellular Matrix Assembly Negative Regulation Of ERK1 And ERK2 Cascade Bud Elongation Involved In Lung Branching Interstitial Matrix Regulation Of Cellular Response To Growth Factor Stimulus Basement Membrane
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