KRTAP12-4 and CH25H

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP12-4	CH25H
Description		keratin associated protein 12-4	cholesterol 25-hydroxylase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Protein Binding	C-4 Methylsterol Oxidase Activity Cholesterol 25-hydroxylase Activity Monooxygenase Activity Iron Ion Binding Protein Binding Steroid Hydroxylase Activity Oxidoreductase Activity Metal Ion Binding
	Biological Process		Lipid Metabolic Process Steroid Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Biosynthetic Process Sterol Biosynthetic Process Response To Type I Interferon B Cell Chemotaxis Negative Regulation Of Cholesterol Metabolic Process Negative Regulation Of Fusion Of Virus Membrane With Host Plasma Membrane
Pathways		Keratinization	Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS			Atrioventricular conduction ( 21041692) Heart failure ( 20445134)
Interacting Genes		51 interacting genes: AQP1 ARID5A ATXN1 ATXN2L CH25H CYSRT1 FBXO34 GPRIN2 HMGB4 HOXA1 IQUB KRTAP11-1 KRTAP12-2 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP6-2 KRTAP8-1 LASP1 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2C LCE3A LCE3D LCE4A LCE5A MEOX2 MGAT5B NBPF19 NOTCH2NLA NR4A3 OLIG2 OTX1 PIH1D2 POU4F2 RBPMS RERE SMCP SPMIP9 SSC4D TEKT5 TRIP13 VENTX	4 interacting genes: CCR4 GPR35 KRTAP12-4 OTX1
Entrez ID		386684	9023
HPRD ID		11200	05183
Ensembl ID		ENSG00000212933	ENSG00000138135
Uniprot IDs		P60329	O95992
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development Intermediate Filament Tissue Development Identical Protein Binding Keratin Filament Protein Binding Sequence-specific DNA Binding Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility	Chemokine Receptor Activity Chemokine-mediated Signaling Pathway Diencephalon Morphogenesis Positive Regulation Of Cytosolic Calcium Ion Concentration Metencephalon Development C-X-C Chemokine Receptor Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Interneuron Migration G Protein-coupled Receptor Activity Cytokine-mediated Signaling Pathway Regulation Of Voltage-gated Calcium Channel Activity Tolerance Induction C-C Chemokine Binding C-C Chemokine Receptor Activity Negative Regulation Of Transporter Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?