MDM4 and CD160

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MDM4	CD160
Gene Name		MDM4, p53 regulator	CD160 molecule
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Plasma Membrane Anchored Component Of Plasma Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Enzyme Binding	Receptor Activity Receptor Binding MHC Class I Receptor Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Cell Proliferation Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Protein Catabolic Process Negative Regulation Of Apoptotic Process G0 To G1 Transition Protein Stabilization Negative Regulation Of Cell Cycle Arrest Cellular Response To Hypoxia	Cellular Defense Response Cell Surface Receptor Signaling Pathway Cell Proliferation Regulation Of Immune Response Defense Response To Gram-negative Bacterium
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS		Breast cancer ( 23535733) Breast Cancer in BRCA1 mutation carriers ( 23544013) Cognitive performance ( 19734545) Prostate cancer ( 23535732)
Protein-Protein Interactions		42 interactors: AKT1 APP ARF1 ATM CAPN7 CASP3 CD160 CDK1 CHEK1 CHEK2 CSNK1A1 E2F1 EP300 LRSAM1 MDM2 MKRN3 MNAT1 PRKAA1 RAD54B RB1 RN5S1@ RNF115 SFN SMAD3 SMAD4 SMARCA2 TP53 TP63 TP73 TRIM46 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 USP7 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	3 interactors: AGTRAP MDM4 TNFRSF14
Entrez ID		4194	11126
HPRD ID		04082	06833
Ensembl ID		ENSG00000198625	ENSG00000117281
Uniprot IDs		O15151 Q59FS6 Q68DC0	B8PRF2 O95971 Q6FH89
PDB IDs		2CR8 2VJE 2VJF 2VYR 3DAB 3EQY 3FDO 3FE7 3FEA 3JZO 3JZP 3JZQ 3LBJ 3U15
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Death Death Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Cell Cycle Process Regulation Of Cell Cycle Positive Regulation Of Mitochondrion Organization Positive Regulation Of Apoptotic Signaling Pathway Mitotic Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Response To Abiotic Stimulus Cellular Response To Stress Cell Cycle Regulation Of Mitochondrion Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Hypoxia Intracellular Signal Transduction Cellular Response To Decreased Oxygen Levels Response To Hypoxia Positive Regulation Of Cell Death Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Cellular Response To Oxygen Levels Response To Stress Regulation Of Cell Death Cellular Response To Stimulus Regulation Of Intracellular Transport Cellular Response To DNA Damage Stimulus Negative Regulation Of Cell Cycle Regulation Of Apoptotic Process Positive Regulation Of Signal Transduction DNA Damage Checkpoint Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Signal Transduction Regulation Of Cellular Component Organization Mitotic Cell Cycle Phase Transition Regulation Of Signal Transduction	G0 To G1 Transition Response To Hypoxia Positive Regulation Of Cytokine Secretion Involved In Immune Response Negative Regulation Of Alpha-beta T Cell Proliferation Angiotensin-activated Signaling Pathway Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of T Cell Migration Negative Regulation Of Cell Cycle Arrest Negative Regulation Of Cell Proliferation Regulation Of T Cell Migration Negative Regulation Of Alpha-beta T Cell Activation Response To Stress Regulation Of Lymphocyte Migration Defense Response To Gram-negative Bacterium Tumor Necrosis Factor-mediated Signaling Pathway Viral Entry Into Host Cell Entry Into Host Cell Positive Regulation Of Cytokine Production Involved In Immune Response Response To Abiotic Stimulus
Tagcloud ?		aberrations abstract along attractive cdk cdk4 checkpoint correlate cyclind developments entered highlights kinases logical make maximizing mdm2 melanoma melanomagenesis p16 preliminary rb rb1 reactivating reactivation reporting summary targeting video	activatory anchored antibodies antigenic bead capacities cd8 coexpression defines ex exhausted exhaustion functionality glycosylphosphatidylinositol gpi herpes hvem immunotherapeutic isoforms jurkat multimerization pbmcs reverses stimulatory synergistically tm triggering viremic warrant
Tagcloud (Difference) ?		aberrations abstract along attractive cdk cdk4 checkpoint correlate cyclind developments entered highlights kinases logical make maximizing mdm2 melanoma melanomagenesis p16 preliminary rb rb1 reactivating reactivation reporting summary targeting video	activatory anchored antibodies antigenic bead capacities cd8 coexpression defines ex exhausted exhaustion functionality glycosylphosphatidylinositol gpi herpes hvem immunotherapeutic isoforms jurkat multimerization pbmcs reverses stimulatory synergistically tm triggering viremic warrant
Tagcloud (Intersection) ?