NCF2 and ACTB

Number of citations of the paper that reports this interaction (PMID 11027608)
8

Data Source:
BioGRID (far western blotting)

		NCF2	ACTB
Gene Name		neutrophil cytosolic factor 2	actin, beta
Image
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Nucleolus Cytoplasm Cytosol Phagolysosome NADPH Oxidase Complex	Nuclear Chromatin Extracellular Space Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Postsynaptic Density Membrane Axon Ribonucleoprotein Complex Cortical Cytoskeleton NuA4 Histone Acetyltransferase Complex Cytoplasmic Ribonucleoprotein Granule Protein Complex Extracellular Vesicular Exosome MLL5-L Complex Blood Microparticle
	Molecular Function	Protein Binding Protein C-terminus Binding Electron Carrier Activity Rac GTPase Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Kinesin Binding Protein Kinase Binding Tat Protein Binding Nucleosomal DNA Binding Nitric-oxide Synthase Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Superoxide Metabolic Process Cellular Defense Response Aging Response To Glucose Response To Activity Response To Lipopolysaccharide Response To Progesterone Cellular Response To Hormone Stimulus Response To Laminar Fluid Shear Stress Response To Drug Superoxide Anion Generation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Positive Regulation Of Neuron Apoptotic Process Innate Immune Response Respiratory Burst Positive Regulation Of Blood Pressure Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Response To Hyperoxia Phagosome Maturation	Retina Homeostasis Chromatin Organization Protein Folding Movement Of Cell Or Subcellular Component Axon Guidance Blood Coagulation Substantia Nigra Development Cell Junction Assembly Adherens Junction Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis ATP-dependent Chromatin Remodeling Cellular Protein Metabolic Process Innate Immune Response Cell-cell Junction Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway 'de Novo' Posttranslational Protein Folding Membrane Organization Platelet Aggregation
Pathways		Signaling by VEGF Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation VEGFA-VEGFR2 Pathway Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System	Axon guidance Gap junction degradation Adherens junctions interactions Translocation of GLUT4 to the plasma membrane L1CAM interactions Recycling pathway of L1 HATs acetylate histones VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling Interaction between L1 and Ankyrins Cell-cell junction organization EPH-ephrin mediated repulsion of cells Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Gap junction trafficking and regulation EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Folding of actin by CCT/TriC Innate Immune System Cell junction organization Protein folding Formation of annular gap junctions Chromatin organization Gap junction trafficking Factors involved in megakaryocyte development and platelet production Chromatin modifying enzymes Signaling by VEGF Chaperonin-mediated protein folding Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ACTB CDC42 CYBA CYBB GOLGA2 KIFAP3 NCF4 PRDX6 PRKDC RAC1 RAC2 S100A8 S100A9 SYTL1	138 interactors: A2M ABLIM1 ABRA ACD ACTC1 ACTG1 AIMP2 ALOX5 ANXA7 AR ARPC1B ATF7IP BBS4 BCL2L1 CAP1 CAP2 CAPZA1 CCT2 CCT4 CCT5 CCT8 CDK5R2 CDKN1A CDKN2A CFL1 CFL2 CLIC4 CLNS1A CNN2 CORO1A CORO7 COTL1 CPNE1 CPNE2 CPNE4 CSNK1A1 CSNK2B CTGF DMTN DNASE1 DSTN DYNLL1 EEF1A1 EHHADH EMD EP300 ERG EZR FABP4 FHL3 FLII GAPDH GNA12 GSN H2AFX HCK HMMR HNRNPAB HNRNPD HNRNPU HSD17B4 KHDRBS1 LASP1 LGALS13 LMNA LMOD1 LRRK2 LYN MAP1B MAP2 MAPT MRGBP MX1 MYO18B MYO1E MYOC NCALD NCF1 NCF2 NEBL NOS2 NRAP NSMAF NT5E P2RX7 PCYT1A PDLIM5 PFDN1 PFDN4 PFN1 PFN2 PHACTR4 PLD1 PLD2 PLG POLR2A POT1 PRKCD PROSER2 PTN RAB4A RAC1 RAC2 RCC1 RPL10A S100A11 SCN10A SHBG SMAD3 SMAD9 SMARCA4 SMN1 SPTAN1 SPTBN2 SSH1 SSH2 SSH3 STX4 SYNJ2BP TANC1 TGM2 TINF2 TK1 TMSB4X TMSB4XP1 TMSB4XP4 TNNI2 TPM1 TPM2 TPM3 TTR VHL VSNL1 WASF1 WASF2 WASF3 WDYHV1 XPO6
Entrez ID		4688	60
HPRD ID		01991	00032
Ensembl ID		ENSG00000116701	ENSG00000075624
Uniprot IDs		P19878	B3KWQ3 P60709 Q1KLZ0
PDB IDs		1E96 1HH8 1K4U 1OEY 1WM5 2DMO	3BYH 3D2U 3LUE
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Innate Immune Response Immune Response Immune System Process Response To Stress Defense Response Single Organismal Cell-cell Adhesion Neutrophil Aggregation Regulation Of Body Fluid Levels Chemotaxis Wound Healing Homotypic Cell-cell Adhesion Hydrogen Peroxide Metabolic Process Organelle Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Sequestering Of Zinc Ion Cell Adhesion Response To External Stimulus Phagosome Maturation Blood Coagulation Inflammatory Response Hemostasis Homeostatic Process Enzyme Linked Receptor Protein Signaling Pathway Leukocyte Migration Antigen Processing And Presentation Of Peptide Antigen Movement Of Cell Or Subcellular Component Hydrogen Peroxide Biosynthetic Process Chemokine Production Regulation Of Hydrogen Peroxide Metabolic Process Sequestering Of Metal Ion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Leukocyte Aggregation Antigen Processing And Presentation Regulation Of Respiratory Burst Respiratory Burst Ephrin Receptor Signaling Pathway Chronic Inflammatory Response Positive Regulation Of Lamellipodium Assembly Interaction With Host Leukocyte Cell-cell Adhesion Leukocyte Chemotaxis Cellular Zinc Ion Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Reactive Oxygen Species Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Regulation Of Cell Projection Assembly	Regulation Of Cellular Component Organization Actin Filament-based Process Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Organelle Organization Regulation Of Cellular Component Size Developmental Process Cell Differentiation Anatomical Structure Development Cell Development Positive Regulation Of Cytoskeleton Organization Anatomical Structure Morphogenesis Regulation Of Actin Filament Polymerization Actin Filament Organization Positive Regulation Of Organelle Organization System Development Negative Regulation Of Actin Filament Polymerization Regulation Of Cell Morphogenesis Multicellular Organismal Development Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Polymerization Regulation Of Protein Complex Assembly Regulation Of Cell Projection Assembly Cellular Component Assembly Cellular Process Movement Of Cell Or Subcellular Component Regulation Of Cell Projection Organization Regulation Of Lamellipodium Assembly Platelet Activation Regulation Of Actin Filament Depolymerization Negative Regulation Of Protein Complex Assembly Regulation Of Cellular Process Cell Morphogenesis Wound Healing Positive Regulation Of Cellular Component Biogenesis Response To Wounding Regulation Of Stress Fiber Assembly Hemostasis Response To Stimulus Cell Death Death Positive Regulation Of Stress Fiber Assembly Apoptotic Process Cell Projection Organization
Tagcloud ?		anion besides biopsies chl copy cyba cybb deleterious deletions downregulation exert hodgkin hybridisation lines lymphoma nadph ncf1 ncf4 oxidase phagocytic profiling progenitors proved quantify recurrent reed sternberg subsets superoxide	18s algorithms bestkeeper cancerous circumstances comparisons examining expressional fluctuated gapdh genorm geometric hspcb lipofectamine normalization normalized normfinder powerful qpcr ranking reagent reagents reference reffinder stably studying thirteen transfection valid
Tagcloud (Difference) ?		anion besides biopsies chl copy cyba cybb deleterious deletions downregulation exert hodgkin hybridisation lines lymphoma nadph ncf1 ncf4 oxidase phagocytic profiling progenitors proved quantify recurrent reed sternberg subsets superoxide	18s algorithms bestkeeper cancerous circumstances comparisons examining expressional fluctuated gapdh genorm geometric hspcb lipofectamine normalization normalized normfinder powerful qpcr ranking reagent reagents reference reffinder stably studying thirteen transfection valid
Tagcloud (Intersection) ?