NCF2 and S100A9

Number of citations of the paper that reports this interaction (PMID 15642721)
28

Data Source:
BioGRID (pull down)

		NCF2	S100A9
Gene Name		neutrophil cytosolic factor 2	S100 calcium binding protein A9
Image
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Nucleolus Cytoplasm Cytosol Phagolysosome NADPH Oxidase Complex	Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein C-terminus Binding Electron Carrier Activity Rac GTPase Binding	Signal Transducer Activity Calcium Ion Binding Protein Binding Microtubule Binding Zinc Ion Binding Antioxidant Activity Toll-like Receptor 4 Binding Arachidonic Acid Binding RAGE Receptor Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Superoxide Metabolic Process Cellular Defense Response Aging Response To Glucose Response To Activity Response To Lipopolysaccharide Response To Progesterone Cellular Response To Hormone Stimulus Response To Laminar Fluid Shear Stress Response To Drug Superoxide Anion Generation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Positive Regulation Of Neuron Apoptotic Process Innate Immune Response Respiratory Burst Positive Regulation Of Blood Pressure Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Response To Hyperoxia Phagosome Maturation	Cytokine Production Leukocyte Migration Involved In Inflammatory Response Chronic Inflammatory Response Positive Regulation Of Peptide Secretion Autophagy Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Inflammatory Response Signal Transduction Cell-cell Signaling Response To Zinc Ion Positive Regulation Of Cell Growth Neutrophil Chemotaxis Actin Cytoskeleton Reorganization Sequestering Of Zinc Ion Response To Lipopolysaccharide Chemokine Production Defense Response To Bacterium Innate Immune Response Regulation Of Integrin Biosynthetic Process Response To Ethanol Positive Regulation Of Inflammatory Response Defense Response To Fungus Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cytoskeleton Organization Neutrophil Aggregation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Signaling by VEGF Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation VEGFA-VEGFR2 Pathway Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ACTB CDC42 CYBA CYBB GOLGA2 KIFAP3 NCF4 PRDX6 PRKDC RAC1 RAC2 S100A8 S100A9 SYTL1	4 interactors: CDC42 EGFR NCF2 S100A8
Entrez ID		4688	6280
HPRD ID		01991	00472
Ensembl ID		ENSG00000116701	ENSG00000163220
Uniprot IDs		P19878	P06702
PDB IDs		1E96 1HH8 1K4U 1OEY 1WM5 2DMO	1IRJ 1XK4 4GGF
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Innate Immune Response Immune Response Immune System Process Response To Stress Defense Response Single Organismal Cell-cell Adhesion Neutrophil Aggregation Regulation Of Body Fluid Levels Chemotaxis Wound Healing Homotypic Cell-cell Adhesion Hydrogen Peroxide Metabolic Process Organelle Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Sequestering Of Zinc Ion Cell Adhesion Response To External Stimulus Phagosome Maturation Blood Coagulation Inflammatory Response Hemostasis Homeostatic Process Enzyme Linked Receptor Protein Signaling Pathway Leukocyte Migration Antigen Processing And Presentation Of Peptide Antigen Movement Of Cell Or Subcellular Component Hydrogen Peroxide Biosynthetic Process Chemokine Production Regulation Of Hydrogen Peroxide Metabolic Process Sequestering Of Metal Ion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Leukocyte Aggregation Antigen Processing And Presentation Regulation Of Respiratory Burst Respiratory Burst Ephrin Receptor Signaling Pathway Chronic Inflammatory Response Positive Regulation Of Lamellipodium Assembly Interaction With Host Leukocyte Cell-cell Adhesion Leukocyte Chemotaxis Cellular Zinc Ion Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Reactive Oxygen Species Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Regulation Of Cell Projection Assembly	Innate Immune Response Immune Response Defense Response Regulation Of Apoptotic Process Regulation Of Cell Death Salivary Gland Morphogenesis Salivary Gland Development Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Exocrine System Development Positive Regulation Of Neuron Apoptotic Process Response To External Stimulus Single Organismal Cell-cell Adhesion Positive Regulation Of DNA Replication Positive Regulation Of Neuron Death Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Chemotaxis Regulation Of ERBB Signaling Pathway Positive Regulation Of Cell Death Immune System Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Hair Follicle Development Hair Cycle Process Positive Regulation Of Inflammatory Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Hair Cycle Positive Regulation Of Transport Reactive Oxygen Species Metabolic Process Positive Regulation Of Intracellular Signal Transduction Alkanesulfonate Metabolic Process Regulation Of DNA Replication Cell Migration Response To Lipid Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Positive Regulation Of DNA Metabolic Process Gland Morphogenesis Positive Regulation Of Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Neutrophil Aggregation Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of Hair Follicle Cell Proliferation Astrocyte Activation Positive Regulation Of Cellular Protein Metabolic Process Response To Stress Submandibular Salivary Gland Formation Actin Filament Branching
Tagcloud ?		anion besides biopsies chl copy cyba cybb deleterious deletions downregulation exert hodgkin hybridisation lines lymphoma nadph ncf1 ncf4 oxidase phagocytic profiling progenitors proved quantify recurrent reed sternberg subsets superoxide	alarmin alarmins allergic amplifiers arthritis biomarker collagen dermatitis imaging immunological inflammation irritative leishmaniasis local locally missing monitor optical phagocyte predict released reliable sensitive serves sub tailoring th1 valuable
Tagcloud (Difference) ?		anion besides biopsies chl copy cyba cybb deleterious deletions downregulation exert hodgkin hybridisation lines lymphoma nadph ncf1 ncf4 oxidase phagocytic profiling progenitors proved quantify recurrent reed sternberg subsets superoxide	alarmin alarmins allergic amplifiers arthritis biomarker collagen dermatitis imaging immunological inflammation irritative leishmaniasis local locally missing monitor optical phagocyte predict released reliable sensitive serves sub tailoring th1 valuable
Tagcloud (Intersection) ?