PRPH and PRPH2

Number of citations of the paper that reports this interaction (PMID 10681511)
34

Data Source:
HPRD (in vitro, in vivo)

		PRPH	PRPH2
Gene Name		peripherin	peripherin 2 (retinal degeneration, slow)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intermediate Filament Neurofilament Membrane Photoreceptor Outer Segment Membrane C-fiber Type III Intermediate Filament Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity
	Biological Process	Intermediate Filament Cytoskeleton Organization	Cell Adhesion Visual Perception Response To Low Light Intensity Stimulus Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 21743467)
Protein-Protein Interactions		5 interactors: KRT15 LMNB1 MYO5A PRPH2 VIM	4 interactors: CNGB1 GRAP2 PRPH ROM1
Entrez ID		5630	5961
HPRD ID		01365	01553
Ensembl ID			ENSG00000112619
Uniprot IDs		B3KWQ6 P41219	P23942
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Filament-based Movement Execution Phase Of Apoptosis Tissue Development Visual Perception Sensory Perception Of Light Stimulus Endoplasmic Reticulum Localization Vesicle Transport Along Actin Filament Response To Low Light Intensity Stimulus Epithelium Development Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Locomotion Involved In Locomotory Behavior Bergmann Glial Cell Differentiation Secretory Granule Localization Camera-type Eye Development Response To Light Intensity Eye Development Long-chain Fatty Acid Biosynthetic Process Melanin Biosynthetic Process Melanin Metabolic Process Intermediate Filament Organization Lens Fiber Cell Development Secondary Metabolite Biosynthetic Process Astrocyte Development Epithelial Cell Differentiation Sensory Organ Development Muscle Filament Sliding Actin-myosin Filament Sliding Actin Filament-based Process Melanosome Transport Lens Fiber Cell Differentiation Pigment Granule Transport Anatomical Structure Development Establishment Of Melanosome Localization Melanocyte Differentiation Intermediate Filament Cytoskeleton Organization Melanosome Localization Insulin Secretion Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Neuroepithelial Cell Differentiation Sensory Perception Developmental Process SMAD Protein Signal Transduction Pigment Biosynthetic Process Cellular Pigmentation Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Transmembrane Transport	Visual Perception Sensory Perception Of Light Stimulus Sensory Perception Retina Development In Camera-type Eye Neurological System Process Response To Low Light Intensity Stimulus Response To Light Stimulus Camera-type Eye Development Eye Development Response To Light Intensity Response To Radiation Camera-type Eye Photoreceptor Cell Differentiation Detection Of Light Stimulus Involved In Visual Perception Protein Heterotetramerization Sensory Organ Development Retina Vasculature Development In Camera-type Eye Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Photoreceptor Cell Maintenance Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process
Tagcloud ?		accumulated albeit autoantibodies autoreactive b c57bl dynamics epitope follicular frequencies genesis heterogeneous infiltrating insulitis invaded islet islets isotype likewise octameric peripherin peritoneum prediabetic preferentially proliferates spleen subsets switched unfolded	accelerated adenoassociated augmentation blinding carrying degenerations electroretinogram incurable inherited insults ipd ipds neuroprotective p347s photoreceptor promise prosurvival prs r26 raav rds retinal rho rosa26 scotopic stat3 tg y705f
Tagcloud (Difference) ?		accumulated albeit autoantibodies autoreactive b c57bl dynamics epitope follicular frequencies genesis heterogeneous infiltrating insulitis invaded islet islets isotype likewise octameric peripherin peritoneum prediabetic preferentially proliferates spleen subsets switched unfolded	accelerated adenoassociated augmentation blinding carrying degenerations electroretinogram incurable inherited insults ipd ipds neuroprotective p347s photoreceptor promise prosurvival prs r26 raav rds retinal rho rosa26 scotopic stat3 tg y705f
Tagcloud (Intersection) ?