PRPH and LCA5L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRPH	LCA5L
Description		peripherin	lebercilin LCA5 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Intermediate Filament Plasma Membrane Membrane Axon Cell Projection Perikaryon Type III Intermediate Filament Extracellular Exosome	Axoneme
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding	Protein Binding
	Biological Process	Intermediate Filament Organization	Intraciliary Transport
Pathways
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS		Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)	Low density lipoprotein cholesterol levels ( 32154731) Pulse pressure ( 30224653) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		34 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT20 KRT24 KRT27 KRT31 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572	19 interacting genes: CCDC136 CCDC197 EXOSC5 FCHSD2 IKBIP KRT75 KRT76 KRT80 KRT81 NMI PBXIP1 PRPH SUV39H2 SYCE1L TFIP11 TPM3 TSGA10IP ZDHHC17 ZGPAT
Entrez ID		5630	150082
HPRD ID		01365	10742
Ensembl ID		ENSG00000135406	ENSG00000157578
Uniprot IDs		B3KWQ6 P41219	O95447 U3KPS7
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Structural Constituent Of Skin Epidermis Structural Constituent Of Cytoskeleton Keratin Filament Supramolecular Fiber Organization Structural Molecule Activity Morphogenesis Of An Epithelium Tissue Morphogenesis Cytoskeleton Organization Epithelial Cell Differentiation Keratin Filament Binding Cytoskeleton Extracellular Exosome Intermediate Filament Cytoskeleton Epidermis Development Protein Binding Organelle Organization Hair Cycle Scaffold Protein Binding Cytoplasmic Stress Granule Nuclear Envelope Organization	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Keratin Filament Supramolecular Fiber Organization
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