PRPH and KRT24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRPH	KRT24
Description		peripherin	keratin 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Intermediate Filament Plasma Membrane Membrane Axon Cell Projection Perikaryon Type III Intermediate Filament Extracellular Exosome	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Intermediate Filament Organization	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS		Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		34 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT20 KRT24 KRT27 KRT31 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572	36 interacting genes: AARD ABI2 ABI3 AIRIM AMOT BFSP2 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT2 KRT20 KRT3 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT78 KRT79 KRT8 KRT80 KRT81 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA
Entrez ID		5630	192666
HPRD ID		01365	09668
Ensembl ID		ENSG00000135406	ENSG00000167916
Uniprot IDs		B3KWQ6 P41219	Q2M2I5
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Structural Constituent Of Skin Epidermis Structural Constituent Of Cytoskeleton Keratin Filament Supramolecular Fiber Organization Structural Molecule Activity Morphogenesis Of An Epithelium Tissue Morphogenesis Cytoskeleton Organization Epithelial Cell Differentiation Keratin Filament Binding Cytoskeleton Extracellular Exosome Intermediate Filament Cytoskeleton Epidermis Development Protein Binding Organelle Organization Hair Cycle Scaffold Protein Binding Cytoplasmic Stress Granule Nuclear Envelope Organization	Intermediate Filament Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Structural Constituent Of Cytoskeleton Cytosol Intermediate Filament Cytoskeleton Extracellular Exosome Actin-based Cell Projection Cytoskeleton Protein Binding Cornified Envelope SCAR Complex Centriole Structural Molecule Activity Peptide Cross-linking Regulation Of Cell Projection Assembly Cell Projection Organization Desmosome
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