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MAP3K3 and MAP3K2
Number of citations of the paper that reports this interaction (PMID
24975362
)
0
Data Source:
BioGRID
(pull down)
MAP3K3
MAP3K2
Gene Name
mitogen-activated protein kinase kinase kinase 3
mitogen-activated protein kinase kinase kinase 2
Image
Gene Ontology Annotations
Cellular Component
Intracellular
Cytosol
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Protein Kinase Activity
MAP Kinase Kinase Activity
MAP Kinase Kinase Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Activity
MAP Kinase Kinase Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Metal Ion Binding
Biological Process
MAPK Cascade
Activation Of MAPKK Activity
Activation Of MAPK Activity
Blood Vessel Development
Intracellular Signal Transduction
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Protein Autophosphorylation
Positive Regulation Of P38MAPK Cascade
Activation Of MAPKK Activity
Activation Of MAPK Activity
Protein Phosphorylation
Activation Of JUN Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Cellular Response To Mechanical Stimulus
Pathways
Signaling by Interleukins
Cytokine Signaling in Immune system
Interleukin-1 signaling
Drugs
Diseases
GWAS
Height (
21998595
22021425
18391951
)
Protein-Protein Interactions
44 interactors:
BIRC2
BRCA1
CDC37
COPS5
GAB1
GLRX3
GTF2I
HSP90AA1
HSP90AB1
HSPA2
IKBKB
MAP2K3
MAP2K4
MAP2K5
MAP2K7
MAP3K2
MAP3K5
MAP3K7
MARK2
MBP
NEDD4
NEDD4L
NFKBIA
PFDN2
PRKACA
RCAN1
RIPK1
SMURF1
SPAG9
SQSTM1
TOM1L1
TRAF6
TRAF7
UBC
VWF
WNK1
XIAP
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZBTB16
25 interactors:
BIRC2
IKBKG
MAP2K3
MAP2K4
MAP2K5
MAP2K7
MAP3K3
MAP3K5
MAPK8
NEDD4
NEDD4L
NFKBIA
PIBF1
PKN2
SH2D2A
SMURF1
STAMBP
STUB1
UBC
USP2
WNK1
XIAP
YWHAE
YWHAG
YWHAZ
Entrez ID
4215
10746
HPRD ID
03965
10068
Ensembl ID
ENSG00000198909
ENSG00000169967
Uniprot IDs
J3KRN4
J3QRB6
Q99759
Q9Y2U5
PDB IDs
2C60
2JRH
2O2V
2PPH
2CU1
2NPT
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Protein Metabolic Process
Activation Of Protein Kinase Activity
Regulation Of Protein Kinase Activity
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Positive Regulation Of Kinase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Signal Transduction
Regulation Of Phosphorus Metabolic Process
Intracellular Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Transferase Activity
Regulation Of Protein Phosphorylation
Positive Regulation Of Signal Transduction
Regulation Of Signaling
Apoptotic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Phosphorylation
Programmed Cell Death
Cell Death
Positive Regulation Of Protein Serine/threonine Kinase Activity
Death
Regulation Of Apoptotic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Phosphorylation
Regulation Of Cell Death
Activation Of MAPK Activity
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Catalytic Activity
MAPK Cascade
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Toll-like Receptor 4 Signaling Pathway
Regulation Of Innate Immune Response
JNK Cascade
Signaling
Response To Stress
Signal Transduction
Apoptotic Signaling Pathway
Positive Regulation Of MAPK Cascade
Positive Regulation Of Intracellular Signal Transduction
Cell Communication
Signal Transduction By Phosphorylation
Positive Regulation Of MAP Kinase Activity
Regulation Of MAP Kinase Activity
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Protein Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Signal Transduction
Intracellular Signal Transduction
Apoptotic Process
Toll-like Receptor 5 Signaling Pathway
Programmed Cell Death
Toll-like Receptor 10 Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Signaling
Toll-like Receptor Signaling Pathway
Cell Death
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Death
Cell Communication
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
MyD88-dependent Toll-like Receptor Signaling Pathway
MAPK Cascade
Activation Of MAPK Activity
Activation Of Innate Immune Response
Positive Regulation Of Protein Metabolic Process
Regulation Of Innate Immune Response
Cellular Response To Stimulus
Signal Transduction By Phosphorylation
Positive Regulation Of Innate Immune Response
Response To Stimulus
Regulation Of Apoptotic Process
Cellular Protein Modification Process
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Regulation Of Cell Death
Positive Regulation Of MAP Kinase Activity
Activation Of Protein Kinase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
JNK Cascade
Regulation Of MAP Kinase Activity
Positive Regulation Of Protein Modification Process
Cellular Response To Stress
Regulation Of Catalytic Activity
Tagcloud
?
11ra
affymetrix
cacna1s
classify
correctly
dataset
erosive
favors
flammatory
ikbkb
nucleoporin
partitioning
paxgene
pbc
pbcs
proin
psa
psoriatic
psors1
psors2
recursive
s100a12
s100a8
shp1
sigirr
tcf7
thioredoxin
tubes
u133a
Tagcloud (Difference)
?
11ra
affymetrix
cacna1s
classify
correctly
dataset
erosive
favors
flammatory
ikbkb
nucleoporin
partitioning
paxgene
pbc
pbcs
proin
psa
psoriatic
psors1
psors2
recursive
s100a12
s100a8
shp1
sigirr
tcf7
thioredoxin
tubes
u133a
Tagcloud (Intersection)
?