Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
MAP3K2 and YWHAZ
Number of citations of the paper that reports this interaction (PMID
9452471
)
16
Data Source:
HPRD
(in vivo)
MAP3K2
YWHAZ
Gene Name
mitogen-activated protein kinase kinase kinase 2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Focal Adhesion
Postsynaptic Density
Cytoplasmic Vesicle Membrane
Cell Leading Edge
Melanosome
Mast Cell Granule
Protein Complex
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Activity
MAP Kinase Kinase Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Metal Ion Binding
Protein Binding
Transcription Factor Binding
Protein Kinase Binding
Protein Domain Specific Binding
Protein Complex Binding
Identical Protein Binding
Poly(A) RNA Binding
Biological Process
Activation Of MAPKK Activity
Activation Of MAPK Activity
Protein Phosphorylation
Activation Of JUN Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Cellular Response To Mechanical Stimulus
Histamine Secretion By Mast Cell
Protein Targeting To Mitochondrion
Apoptotic Process
Signal Transduction
Blood Coagulation
Gene Expression
Platelet Activation
Response To Drug
Negative Regulation Of Apoptotic Process
Establishment Of Golgi Localization
Membrane Organization
Golgi Reassembly
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
Translocation of GLUT4 to the plasma membrane
Activation of BH3-only proteins
Signaling by Wnt
deactivation of the beta-catenin transactivating complex
Rap1 signalling
RNF mutants show enhanced WNT signaling and proliferation
Programmed Cell Death
XAV939 inhibits tankyrase, stabilizing AXIN
Intrinsic Pathway for Apoptosis
Regulation of mRNA stability by proteins that bind AU-rich elements
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
Cytokine Signaling in Immune system
Activation of BAD and translocation to mitochondria
Signaling by Interleukins
TCF dependent signaling in response to WNT
KSRP destabilizes mRNA
GP1b-IX-V activation signalling
Signaling by WNT in cancer
Platelet activation, signaling and aggregation
Interleukin-3, 5 and GM-CSF signaling
Adaptive Immune System
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder and conduct disorder (
18951430
)
Protein-Protein Interactions
25 interactors:
BIRC2
IKBKG
MAP2K3
MAP2K4
MAP2K5
MAP2K7
MAP3K3
MAP3K5
MAPK8
NEDD4
NEDD4L
NFKBIA
PIBF1
PKN2
SH2D2A
SMURF1
STAMBP
STUB1
UBC
USP2
WNK1
XIAP
YWHAE
YWHAG
YWHAZ
191 interactors:
AANAT
ABL1
ADAM22
ADRA2A
ADRA2B
ADRA2C
AKAP13
AKT1
APP
ARAF
ARHGEF2
ATP5A1
ATXN1
BAD
BCAR1
BCR
BRAF
BSPRY
CBL
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK16
CDK17
CDKN1B
CENPJ
CFL1
CGNL1
CLIC4
CRTC2
CSF2RB
CSNK1A1
CSNK1D
DFFA
DISC1
EFNB3
EGFR
EIF3A
ENO1
EPB41L1
EPB41L2
EPB41L3
EXO1
FAM13B
FAM53C
FHOD1
FOXO1
FOXO3
FOXO4
GABARAPL2
GABBR1
GCH1
GP1BA
GP1BB
GP5
HDAC4
HDAC9
HIST1H3A
HIVEP2
HMGN1
HSPA1A
HSPA1B
IGF1R
IL9R
ING1
INPP5A
IRS1
IRS2
KCNK15
KCNK3
KCNK9
KIAA0232
KIAA0930
KIAA1377
KIF1C
KIF5B
KLC2
KLC4
KLF11
KRT18
KSR1
LARP1
LCP2
LIMK1
LRMP
LYST
MADD
MAP2K5
MAP3K2
MAP3K3
MAP3K4
MAP3K5
MAPK8
MAPKAPK2
MAPT
MARK2
MARK3
MARK4
MDM4
MEF2C
MINK1
MLF1
MPHOSPH9
MSL2
MST1R
MYH9
NEDD4L
NFATC2
NFATC4
NR4A1
PAK1
PAK4
PARD3
PARD6A
PARD6B
PDC
PFKFB2
PIAS1
PPP1CC
PPP1R14A
PRDX2
PRKCA
PRKCD
PRKCI
PRKCZ
PRKD1
PRLR
PRMT5
PSMA5
PTPN13
PTPRO
RAF1
RALGPS2
RAP1GAP2
RASAL3
REM1
RFWD2
RGS3
RIN1
RMDN3
RPRD1A
RRAD
SAMSN1
SH3GL1
SIK1
SIK3
SIMC1
SLC8A2
SNX24
SORBS2
SQSTM1
SSFA2
SSX2IP
STK25
STK38
SYN2
SYNPO
SYNPO2
TAB2
TBXA2R
TERT
TH
TJP2
TLK2
TNFAIP3
TNS1
TP53
TPD52L1
TPH1
TRA2B
TRIM21
TSC1
TSC2
TUBB
UBC
UBE3A
UCHL5
UCP2
UCP3
VCP
VIM
WEE1
WNK1
WNK2
WWTR1
XRCC6
YWHAE
ZAK
ZNF839
Entrez ID
10746
7534
HPRD ID
10068
03183
Ensembl ID
ENSG00000169967
ENSG00000164924
Uniprot IDs
Q9Y2U5
D0PNI1
P63104
PDB IDs
2CU1
2NPT
1IB1
1QJA
1QJB
2C1J
2C1N
2O02
2WH0
3CU8
3NKX
3RDH
4BG6
4FJ3
4HKC
4IHL
Enriched GO Terms of Interacting Partners
?
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Protein Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Signal Transduction
Intracellular Signal Transduction
Apoptotic Process
Toll-like Receptor 5 Signaling Pathway
Programmed Cell Death
Toll-like Receptor 10 Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Signaling
Toll-like Receptor Signaling Pathway
Cell Death
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Death
Cell Communication
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
MyD88-dependent Toll-like Receptor Signaling Pathway
MAPK Cascade
Activation Of MAPK Activity
Activation Of Innate Immune Response
Positive Regulation Of Protein Metabolic Process
Regulation Of Innate Immune Response
Cellular Response To Stimulus
Signal Transduction By Phosphorylation
Positive Regulation Of Innate Immune Response
Response To Stimulus
Regulation Of Apoptotic Process
Cellular Protein Modification Process
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Regulation Of Cell Death
Positive Regulation Of MAP Kinase Activity
Activation Of Protein Kinase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
JNK Cascade
Regulation Of MAP Kinase Activity
Positive Regulation Of Protein Modification Process
Cellular Response To Stress
Regulation Of Catalytic Activity
Intracellular Signal Transduction
Cell Communication
Regulation Of Phosphorylation
Cellular Response To Stimulus
Regulation Of Phosphorus Metabolic Process
Signaling
Regulation Of Cellular Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Protein Metabolic Process
Response To Stimulus
Signal Transduction
Regulation Of Kinase Activity
Regulation Of Cellular Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Protein Phosphorylation
Positive Regulation Of Metabolic Process
Regulation Of Signaling
Regulation Of Protein Kinase Activity
Response To Stress
Cellular Response To Growth Factor Stimulus
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of Signal Transduction
Protein Phosphorylation
Neurotrophin Signaling Pathway
Response To Growth Factor
Positive Regulation Of Cellular Metabolic Process
Cellular Protein Modification Process
Response To Organic Substance
Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Phosphorylation
Cellular Response To Organic Substance
Regulation Of Metabolic Process
Positive Regulation Of Catalytic Activity
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Death
Regulation Of MAPK Cascade
Apoptotic Process
Cell Death
Death
Programmed Cell Death
Positive Regulation Of Protein Modification Process
Phosphate-containing Compound Metabolic Process
Regulation Of Apoptotic Process
Innate Immune Response
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Cellular Component Organization
Tagcloud
?
actb
arfgap2
arl1
bestkeeper
bmi1
casc3
cynomolgus
ddx3x
gapdh
genorm
lists
monkey
morf4
mrfap1
normalization
normfinder
ormdl1
prerequisite
reference
ribosylation
rps19
rsl24d1
sar1a
traditionally
transcriptome
usp22
vitally
zc3h11a
zranb2
Tagcloud (Difference)
?
actb
arfgap2
arl1
bestkeeper
bmi1
casc3
cynomolgus
ddx3x
gapdh
genorm
lists
monkey
morf4
mrfap1
normalization
normfinder
ormdl1
prerequisite
reference
ribosylation
rps19
rsl24d1
sar1a
traditionally
transcriptome
usp22
vitally
zc3h11a
zranb2
Tagcloud (Intersection)
?