CCL3L3 and SGTB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCL3L3	SGTB
Description		C-C motif chemokine ligand 3 like 3	small glutamine rich tetratricopeptide repeat co-chaperone beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Membrane TRC Complex
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding Hsp70 Protein Binding Identical Protein Binding Protein-folding Chaperone Binding Molecular Adaptor Activity
	Biological Process	Chemotaxis Inflammatory Response Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Protein Homooligomerization Protein Heterooligomerization
Pathways		Chemokine receptors bind chemokines Interleukin-10 signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intralaminar thalamic nuclei volume ( 34006833) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: ACKR2 CCR5 MGST2 SGTB SLC41A3 TMEM179B	116 interacting genes: ABCG4 ADAT2 ADIPOQ AGR2 AGR3 ASPH BTC C1QA C1QL4 C1QTNF5 C1QTNF6 C5orf46 CALR CCL3L3 CD200R1 CD3D CD68 CD79B CD99L2 CDH15 CDSN CMPK1 COL10A1 COL1A2 COLQ COMP CREB3L3 CSH1 CSH2 CTAG1A CTAG1B CYB5R1 DEFA6 DEXI DMKN ECM1 EFEMP2 EMCN ERP29 ETNK1 EVA1A FBN1 FGF21 FZD7 GALNT11 GGH GIP GPX7 GYPA HSP90B1 HSPA13 IL6R IL6ST ITPRIP ITPRIPL1 KCNE5 KRT1 LAMP3 LAT LCN2 LHB LMO2 MYDGF NAXD NME3 OSMR PAGE3 PDIA6 PGRMC1 PODXL PPIB PPIC PRAP1 PRB1 PRB3 PRB4 PRR4 PSORS1C2 RAI2 RCN1 RNASE10 RNF144A RNF144B RNF170 SDC4 SDF2L1 SELENOM SERPINE1 SERPINF1 SERPINI2 SGCA SGTA SHISA5 SIL1 SLPI SOD3 SPINK4 SPP1 SRGN SYT11 SYT4 TFF1 TMEM108 TMEM123 TMPO TMUB1 TNFRSF19 TNFSF13 TXNDC12 UBL4A UPK3A VEGFC VWC2 WFDC12 ZG16 ZG16B
Entrez ID		414062	54557
HPRD ID		14426	18049
Ensembl ID		ENSG00000276085	ENSG00000197860
Uniprot IDs		P16619	Q96EQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Chemokine-mediated Signaling Pathway Chemokine (C-C Motif) Ligand 5 Binding TRC Complex Mitochondrial Magnesium Ion Transmembrane Transport Magnesium:sodium Antiporter Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Receptor Decoy Activity Calcium-mediated Signaling Leukotriene-C4 Synthase Activity Cell Chemotaxis Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Response To Molecule Of Bacterial Origin Response To Lipopolysaccharide Locomotion Dendritic Cell Chemotaxis Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Sarcoplasmic Reticulum Calcium Ion Transport Negative Regulation Of Macrophage Apoptotic Process External Side Of Plasma Membrane Plasma Membrane Chemotaxis Membrane Glutathione Biosynthetic Process Glutathione Binding Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Magnesium Ion Transport Magnesium Ion Transmembrane Transport Magnesium Ion Transmembrane Transporter Activity Monoatomic Cation Transmembrane Transporter Activity Leukotriene Biosynthetic Process G Protein-coupled Receptor Activity Negative Regulation Of Myeloid Cell Apoptotic Process Glutathione Peroxidase Activity Cytokine-mediated Signaling Pathway Dendritic Cell Migration Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Peptide Biosynthetic Process Response To Cholesterol Protein Heterooligomerization Glutathione Transferase Activity Protein Targeting To ER Leukotriene Metabolic Process Regulation Of Myeloid Cell Apoptotic Process Establishment Of Protein Localization To Endoplasmic Reticulum	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Protein Binding Collagen Trimer Endoplasmic Reticulum Chaperone Complex Endoplasmic Reticulum Extracellular Matrix Protein Folding Smooth Endoplasmic Reticulum Extracellular Matrix Structural Constituent Serine-type Endopeptidase Inhibitor Activity Sarcoplasmic Reticulum Lumen Extracellular Exosome Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Melanosome Response To Bacterium Hormone Activity Interleukin-6 Receptor Complex Ciliary Neurotrophic Factor Receptor Complex Oncostatin-M Receptor Activity Positive Regulation Of Transport Memory Response To Endoplasmic Reticulum Stress Defense Response To Bacterium Ciliary Neurotrophic Factor Receptor Activity Interleukin-11 Receptor Activity Interleukin-11 Binding Oncostatin-M-mediated Signaling Pathway Regulation Of Smooth Muscle Cell-matrix Adhesion Regulation Of Immune System Process Sequestering Of Calcium Ion Biomineral Tissue Development Basement Membrane Ciliary Neurotrophic Factor-mediated Signaling Pathway ERAD Pathway Growth Factor Activity Golgi Lumen Positive Regulation Of Acute Inflammatory Response Ciliary Neurotrophic Factor Receptor Binding Response To Stress Regulation Of Cell-substrate Adhesion
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