CCL3L3 and SLC41A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCL3L3	SLC41A3
Description		C-C motif chemokine ligand 3 like 3	solute carrier family 41 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding Monoatomic Cation Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Magnesium:sodium Antiporter Activity
	Biological Process	Chemotaxis Inflammatory Response Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway	Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transmembrane Transport Mitochondrial Magnesium Ion Transmembrane Transport
Pathways		Chemokine receptors bind chemokines Interleukin-10 signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Bell's palsy ( 33602968)
Interacting Genes		6 interacting genes: ACKR2 CCR5 MGST2 SGTB SLC41A3 TMEM179B	17 interacting genes: APP ARLN CCL3L3 CCR2 CREB3 GPR37 IGFBP5 MAPK6 NHERF4 NPSR1 PLP1 REL SMCO4 SMO SUFU TMBIM6 TSPO2
Entrez ID		414062	54946
HPRD ID		14426	11580
Ensembl ID		ENSG00000276085	ENSG00000114544
Uniprot IDs		P16619	Q96GZ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Chemokine-mediated Signaling Pathway Chemokine (C-C Motif) Ligand 5 Binding TRC Complex Mitochondrial Magnesium Ion Transmembrane Transport Magnesium:sodium Antiporter Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Receptor Decoy Activity Calcium-mediated Signaling Leukotriene-C4 Synthase Activity Cell Chemotaxis Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Response To Molecule Of Bacterial Origin Response To Lipopolysaccharide Locomotion Dendritic Cell Chemotaxis Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Sarcoplasmic Reticulum Calcium Ion Transport Negative Regulation Of Macrophage Apoptotic Process External Side Of Plasma Membrane Plasma Membrane Chemotaxis Membrane Glutathione Biosynthetic Process Glutathione Binding Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Magnesium Ion Transport Magnesium Ion Transmembrane Transport Magnesium Ion Transmembrane Transporter Activity Monoatomic Cation Transmembrane Transporter Activity Leukotriene Biosynthetic Process G Protein-coupled Receptor Activity Negative Regulation Of Myeloid Cell Apoptotic Process Glutathione Peroxidase Activity Cytokine-mediated Signaling Pathway Dendritic Cell Migration Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Peptide Biosynthetic Process Response To Cholesterol Protein Heterooligomerization Glutathione Transferase Activity Protein Targeting To ER Leukotriene Metabolic Process Regulation Of Myeloid Cell Apoptotic Process Establishment Of Protein Localization To Endoplasmic Reticulum	Positive Regulation Of Monocyte Chemotaxis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Signal Transduction Positive Regulation Of Locomotion Locomotion Regulation Of Signal Transduction Spinal Cord Dorsal/ventral Patterning Regulation Of Calcium Ion Transport G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Mononuclear Cell Migration Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Astrocyte Activation Neuropeptide Receptor Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Migration Chemotaxis Regulation Of Metal Ion Transport Regulation Of Cell Motility Regulation Of Intracellular Signal Transduction Regulation Of Calcium Ion Transmembrane Transport Regulation Of Locomotion Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Endoplasmic Reticulum Positive Regulation Of Leukocyte Migration G Protein-coupled Receptor Activity Hair Follicle Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Transport Amyloid-beta Complex Growth Cone Lamellipodium Intracellular Signal Transduction Regulation Of Monoatomic Ion Transport Regulation Of Response To Calcium Ion Positive Regulation Of Cell Communication Dendrite Amylin Binding Positive Regulation Of Signaling Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of T Cell Migration Positive Regulation Of Signal Transduction Dendrite Development
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