KRT82 and VAC14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT82	VAC14
Description		keratin 82	VAC14 component of PIKFYVE complex
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Golgi Membrane Endosome Endoplasmic Reticulum Cytosol Endosome Membrane Membrane Early Endosome Membrane Late Endosome Membrane PAS Complex Presynaptic Endosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Keratinization Intermediate Filament Organization	Phosphatidylinositol Biosynthetic Process Signal Transduction Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways		Keratinization Formation of the cornified envelope	Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524)	Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Pulse pressure ( 28135244)
Interacting Genes		15 interacting genes: COL8A1 HGS HOXA1 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT40 PLSCR4 VAC14	107 interacting genes: ABHD11 ACSS1 ACTMAP AMT APP ARID5A ASB13 ATM BCL2L1 BHLHE40 BKGD C4orf33 CASP1 CATSPERT CD209 CDRT4 CNTN2 COL8A1 CRK CRYBA1 CRYBA2 DDAH2 DNAAF19 EEF1AKMT3 EHHADH EIF2S1 EIF6 FAM50B FNDC3B GABPB2 GALT GINS3 GLIS2 GNB1 GTF3C2 HDHD3 HNF1B HNRNPLL INTS11 JMJD7 KHDC1 KRABD5 KRT82 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LINC00518 LPAL2 MBLAC1 MEOX2 METTL15 MGAT5B MPPED2 MTMR9 MVP MYOZ1 NDUFAB1 NGB NOS1 NTAQ1 OIT3 OTOS PBLD PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PPP6C PRADC1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX2 RHBDL1 RHOXF2 RIPPLY1 RNASEH2C RSKR SIGLEC5 SMUG1 SNF8 SPMIP9 SPRYD7 SRPK2 TCEANC TP53BP1 TRIM55 TRIM63 UFSP1 VENTX VHLL WDR83 WRAP53 ZBTB49 ZCWPW1 ZNF34
Entrez ID		3888	55697
HPRD ID		03048	07660
Ensembl ID		ENSG00000161850	ENSG00000103043
Uniprot IDs		Q9NSB4	Q08AM6
PDB IDs			7K1Y
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Anatomical Structure Morphogenesis Cytoskeleton Organization Cytoskeleton Cell Differentiation Organelle Organization Structural Constituent Of Cytoskeleton Cellular Developmental Process Epidermis Development Extracellular Exosome Hair Cycle Developmental Process Cytosol Semicircular Canal Formation PAS Complex Collagen Type VIII Trimer Abducens Nerve Formation Optokinetic Behavior Terminal Web ESCRT-0 Complex Calcium Activated Phosphatidylserine Scrambling Tissue Development Phagocytic Vesicle Lumen Calcium Activated Phosphatidylcholine Scrambling Calcium Activated Phospholipid Scrambling	Protein Binding Intermediate Filament
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