RAB11FIP3 and ARF4

Number of citations of the paper that reports this interaction (PMID 11481332)
33

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		RAB11FIP3	ARF4
Gene Name		RAB11 family interacting protein 3 (class II)	ADP-ribosylation factor 4
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Endosome Centrosome Microtubule Organizing Center Cytosol Midbody Cleavage Furrow Intracellular Membrane-bounded Organelle Intercellular Bridge Recycling Endosome Recycling Endosome Membrane	Golgi Apparatus Cytosol Membrane Ruffle Membrane Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Rab GTPase Binding ADP-ribosylation Factor Binding Protein Homodimerization Activity	GTPase Activity Epidermal Growth Factor Receptor Binding Protein Binding GTP Binding
	Biological Process	Cytokinesis Organelle Organization Vesicle-mediated Transport Endocytic Recycling	Protein ADP-ribosylation Organelle Organization Epidermal Growth Factor Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Brain Development Protein Transport Vesicle-mediated Transport Cell Migration Activation Of Phospholipase D Activity Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Axon Injury Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium Assembly of the primary cilium	Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium Assembly of the primary cilium
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ARF4 ARF5 ARF6 IKBKG RAB11A RAB11B RAB11FIP4 RAB25 TOMM34	6 interactors: ADRB2 EGFR HNRNPD RAB11FIP3 RCHY1 SDCBP2
Entrez ID		9727	378
HPRD ID		18521	03107
Ensembl ID		ENSG00000090565	ENSG00000168374
Uniprot IDs		O75154	P18085
PDB IDs		2D7C 2HV8	1Z6X
Enriched GO Terms of Interacting Partners?		Small GTPase Mediated Signal Transduction Protein Transport Establishment Of Protein Localization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Intracellular Signal Transduction Establishment Of Vesicle Localization Protein Localization Vesicle Localization Cellular Pigmentation Rab Protein Signal Transduction Vesicle-mediated Transport Establishment Of Organelle Localization Regulation Of Vesicle-mediated Transport Pigmentation Organelle Localization Transport Cellular Protein Localization Ras Protein Signal Transduction Cellular Localization Exocytosis Intracellular Protein Transport Multivesicular Body Assembly Regulation Of Multivesicular Body Size Establishment Of Localization In Cell Positive Regulation Of Epithelial Cell Migration Cell Division Signal Transduction Cytokinesis Secretion By Cell Protein Localization To Organelle Constitutive Secretory Pathway Multivesicular Body Organization Signaling Cell Communication Pseudopodium Organization Regulation Of Endosome Size Regulation Of Epithelial Cell Migration Secretion Exosomal Secretion Intracellular Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Response To Stimulus Regulation Of Protein Localization Endosomal Transport Myeloid Cell Apoptotic Process Cellular Response To Acidic PH Plasma Membrane To Endosome Transport	Regulation Of Vasodilation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Alkanesulfonate Metabolic Process Positive Regulation Of Protein Ubiquitination Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Regulation Of Cellular Protein Metabolic Process Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Circadian Rhythm Regulation Of Protein Metabolic Process Activation Of Phospholipase A2 Activity Positive Regulation Of Protein Modification Process Regulation Of Protein Ubiquitination Endosomal Transport Positive Regulation Of Phospholipase A2 Activity Cellular Localization Response To Cobalamin Response To UV-A Circadian Regulation Of Translation Heat Generation Response To Hydroxyisoflavone Diet Induced Thermogenesis Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Activation Of Protein Kinase Activity Rhythmic Process Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Positive Regulation Of Catenin Import Into Nucleus Regulation Of Phospholipase A2 Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Superoxide Anion Generation Magnesium Ion Homeostasis Negative Regulation Of Smooth Muscle Contraction Regulation Of Protein Catabolic Process Adrenergic Receptor Signaling Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Response To Dietary Excess Intracellular Transport Response To Nutrient Levels Positive Regulation Of Gene Expression Cellular Response To Estradiol Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Multicellular Organism Growth Protein Insertion Into Membrane
Tagcloud ?			apparatus arf1 arf3 arf5 arf6 arfs carrier coated complementary endocytic endocytosed endosomes former furin golgi gtpases localize overlapping pair recycling redundantly retrograde ribosylation tgn tgn38 transferrin trigger tubulation
Tagcloud (Difference) ?			apparatus arf1 arf3 arf5 arf6 arfs carrier coated complementary endocytic endocytosed endosomes former furin golgi gtpases localize overlapping pair recycling redundantly retrograde ribosylation tgn tgn38 transferrin trigger tubulation
Tagcloud (Intersection) ?