RAB11FIP3 and RAB25

Number of citations of the paper that reports this interaction (PubMedID 11495908)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro, in vivo)

		RAB11FIP3	RAB25
Description		RAB11 family interacting protein 3	RAB25, member RAS oncogene family
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GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Cytoplasm Mitochondrion Endosome Golgi Apparatus Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Endosome Membrane Membrane Endocytic Vesicle Midbody Cytoplasmic Vesicle Membrane Endocytic Vesicle Membrane Cleavage Furrow Trans-Golgi Network Membrane Centriolar Satellite Ciliary Basal Body Intercellular Bridge Recycling Endosome Recycling Endosome Membrane Bounding Membrane Of Organelle Postsynaptic Recycling Endosome Membrane	Golgi Apparatus Plasma Membrane Membrane Pseudopodium Pseudopodium Membrane Cytoplasmic Vesicle Cell Projection Recycling Endosome Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding GTPase Binding Dynein Light Intermediate Chain Binding Molecular Adaptor Activity	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Myosin V Binding
	Biological Process	Mitotic Cytokinesis Vesicle Docking Involved In Exocytosis Microtubule-based Movement Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Cilium Assembly Cell Division Regulation Of Vesicle-mediated Transport Early Endosome To Recycling Endosome Transport Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion Regulation Of Cilium Assembly Regulation Of Early Endosome To Recycling Endosome Transport Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Protein Localization To Centrosome Protein Localization To Cleavage Furrow Regulation Of Endocytic Recycling	Epithelial Cell Morphogenesis Exocytosis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Epithelial Cell Migration Protein Transport Pseudopodium Organization Regulation Of Vesicle-mediated Transport
Pathways		VxPx cargo-targeting to cilium	RAB geranylgeranylation
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 27863252 32888494) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 32888494)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Parkinson's disease ( 32201043)
Interacting Genes		9 interacting genes: ARF4 ARF5 ARF6 ASAP1 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34	14 interacting genes: ACVR1 BMPR1B ITGB1 MED31 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SH3BP5L SMAD4 SMURF2 TGFBR1
Entrez ID		9727	57111
HPRD ID		18521	06698
Ensembl ID		ENSG00000090565	ENSG00000132698
Uniprot IDs		O75154	P57735
PDB IDs		2D7C 2HV8 4D0M 4UJ3 4UJ4	2OIL 3TSO
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding Protein Localization To Cilium Golgi Apparatus G Protein Activity Endocytic Recycling Myosin V Binding Recycling Endosome Membrane Intracellular Protein Localization Vesicle-mediated Transport Intracellular Transport Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Protein Localization To Cleavage Furrow Establishment Of Protein Localization Positive Regulation Of Epithelial Cell Migration Plasma Membrane Bounded Cell Projection Organization Cleavage Furrow Cellular Localization Establishment Of Localization In Cell Regulation Of Cell Projection Assembly Positive Regulation Of Mitotic Cytokinetic Process Amyloid-beta Clearance By Transcytosis Regulation Of Epithelial Cell Migration Protein Transport Endosomal Transport Cell Projection Organization Regulation Of Cytokinesis Protein Localization To Organelle Regulation Of Cilium Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Transcytosis Regulation Of Endocytic Recycling Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Amyloid-beta Clearance Regulation Of Cell Division Protein Localization To Cell Surface Nucleotide Binding Localization Within Membrane Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Exocytosis Regulation Of Protein Localization To Cell Surface	SMAD Binding Recycling Endosome Negative Regulation Of Adiponectin Secretion Transforming Growth Factor Beta Receptor Activity, Type I Transmembrane Receptor Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cell Communication Negative Regulation Of Signaling Transforming Growth Factor Beta Receptor Signaling Pathway Endosome Recycling Endosome Membrane Activin Receptor Signaling Pathway Cellular Response To BMP Stimulus Small GTPase Binding Ventricular Septum Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Activin Receptor Complex Activin Receptor Activity, Type I Pattern Specification Process BMP Receptor Activity Positive Regulation Of Epithelial To Mesenchymal Transition Germ Cell Migration Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Vesicle-mediated Transport Negative Regulation Of Hormone Secretion Regulation Of SMAD Protein Signal Transduction Cardiac Septum Morphogenesis Positive Regulation Of Extracellular Matrix Assembly Endothelial Cell Activation Negative Regulation Of Protein Secretion Activin Binding BMP Signaling Pathway In Utero Embryonic Development Insulin Secretion Involved In Cellular Response To Glucose Stimulus Chordate Embryonic Development Regulation Of Hormone Secretion Regulation Of Hormone Levels Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Regionalization Cellular Response To Growth Factor Stimulus I-SMAD Binding Gastrulation With Mouth Forming Second Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulated Exocytosis Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Communication Pharyngeal System Development Regulation Of Signaling
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