INSR and SOCS1

  • Number of citations of the paper that reports this interaction (PMID 15169905)
  • 103
  • Data Source:
  • HPRD (in vitro, two hybrid)

INSR

SOCS1

Gene Name insulin receptor suppressor of cytokine signaling 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 77 interactors: ACP1 ADRB2 AHSG ARF1 ARHGAP26 CALM1 CALM2 CALM3 CAV1 CAV3 CBL CEACAM1 CRK CRKL CSK DOK1 DOK4 DOK5 ENPP1 FABP4 FRS2 GAB1 GNB2L1 GRB10 GRB14 GRB7 HRAS IGF1R IGF2 INS INSRR IRF7 IRS1 IRS2 JAK1 JAK2 KHDRBS1 KRT27 KRT31 MAD2L1 MAPK3 PIK3R1 PIK3R3 PLCG1 PRKCA PRKCD PTK2 PTPN1 PTPN11 PTPN12 PTPN2 PTPN6 PTPRC PTPRF RAF1 RASA1 SH2B1 SH2B2 SHC1 SMAD2 SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS2 SOCS3 SOCS6 SORBS1 SRC STAT5A STAT5B SYNCRIP TEAD1 VAV1 VAV3 YWHAB 40 interactors: ATM AXL COMMD1 CRK CSF1 CSF1R CXCR4 CYTIP EGFR ERBB2 FLT3 FYN GHR GRB2 IFNGR1 IGF1R IL2RB INSR IRS1 IRS2 ITK JAK1 JAK2 JAK3 KIT MPL NCK1 PDGFRB PIK3R1 PIK3R2 PIM2 RELA TCEB1 TCEB2 TEC TEK TIRAP TRIM8 VAV1 VAV2
Entrez ID 3643 8651
HPRD ID 00975 04669
Ensembl ID ENSG00000171105 ENSG00000185338
Uniprot IDs P06213 O15524 Q4JHT5
PDB IDs 1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA 3LOH 3W11 3W12 3W13 3W14 4IBM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
Tagcloud (Difference) ?
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
Tagcloud (Intersection) ?