INSR and SOCS6

  • Number of citations of the paper that reports this interaction (PMID 11342531)
  • 38
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

INSR

SOCS6

Gene Name insulin receptor suppressor of cytokine signaling 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Systemic lupus erythematosus ( 18204098)
Protein-Protein Interactions 77 interactors: ACP1 ADRB2 AHSG ARF1 ARHGAP26 CALM1 CALM2 CALM3 CAV1 CAV3 CBL CEACAM1 CRK CRKL CSK DOK1 DOK4 DOK5 ENPP1 FABP4 FRS2 GAB1 GNB2L1 GRB10 GRB14 GRB7 HRAS IGF1R IGF2 INS INSRR IRF7 IRS1 IRS2 JAK1 JAK2 KHDRBS1 KRT27 KRT31 MAD2L1 MAPK3 PIK3R1 PIK3R3 PLCG1 PRKCA PRKCD PTK2 PTPN1 PTPN11 PTPN12 PTPN2 PTPN6 PTPRC PTPRF RAF1 RASA1 SH2B1 SH2B2 SHC1 SMAD2 SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS2 SOCS3 SOCS6 SORBS1 SRC STAT5A STAT5B SYNCRIP TEAD1 VAV1 VAV3 YWHAB 22 interactors: ACVR1 BMPR1B EFEMP1 INSR IRS2 IRS4 KDM1A KIT PIK3R1 PIK3R2 RBCK1 RELA SMURF2 TCEB1 TCEB2 TGFBR1 TUBA1A TUBB4B UBE2D2 UBE2I WDR89 ZMIZ2
Entrez ID 3643 9306
HPRD ID 00975 05491
Ensembl ID ENSG00000171105 ENSG00000170677
Uniprot IDs P06213 O14544
PDB IDs 1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA 3LOH 3W11 3W12 3W13 3W14 4IBM 2VIF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
6r  c3  castration  cis  constitutively  crpc  erk1  exogenous  express  gp130  il  jak1  jak2  jak3  lncap  ned  neuroendocrine  s17  secretes  sh2  slightly  socs1  socs7  stat3  subline  sublines  suppressors  though  tyk2 
Tagcloud (Difference) ?
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
6r  c3  castration  cis  constitutively  crpc  erk1  exogenous  express  gp130  il  jak1  jak2  jak3  lncap  ned  neuroendocrine  s17  secretes  sh2  slightly  socs1  socs7  stat3  subline  sublines  suppressors  though  tyk2 
Tagcloud (Intersection) ?