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AQP1 and LIME1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
AQP1
LIME1
Description
aquaporin 1 (Colton blood group)
Lck interacting transmembrane adaptor 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Brush Border
Basal Plasma Membrane
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Axon
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Ankyrin-1 Complex
Extracellular Space
Plasma Membrane
Membrane
B Cell Receptor Complex
Molecular Function
Intracellularly CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Channel Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Ephrin Receptor Binding
Hydrogen Peroxide Channel Activity
Protein Binding
Protein Kinase Binding
Biological Process
Renal Water Homeostasis
Glomerular Filtration
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Intracellular Water Homeostasis
Fibroblast Migration
Positive Regulation Of Fibroblast Migration
Carbon Dioxide Transport
Glycerol Transmembrane Transport
Cell Migration
Sensory Perception Of Pain
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Secretion By Cell
Cerebrospinal Fluid Secretion
Secretory Granule Organization
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Wound Healing
Odontogenesis
Negative Regulation Of Apoptotic Process
Lipid Digestion
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Camera-type Eye Morphogenesis
Defense Response To Gram-negative Bacterium
Multicellular Organismal-level Water Homeostasis
Corticotropin Secretion
Establishment Of Localization In Cell
Transmembrane Transport
Renal Water Absorption
Cellular Response To Hydrogen Peroxide
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Metanephric Glomerulus Vasculature Development
Ammonium Transmembrane Transport
Hydrogen Peroxide Transmembrane Transport
Monoatomic Cation Transmembrane Transport
Adaptive Immune Response
Immune System Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Canonical NF-kappaB Signal Transduction
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Developmental Lineage of Pancreatic Ductal Cells
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Fractures (
30598549
)
Heel bone mineral density (
28869591
30598549
)
hemolysis of donated blood (osmotic) (
34014839
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Triglyceride levels (
34074324
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Asthma (
31619474
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Bell's palsy (
33602968
)
Crohn's disease (
28067908
)
Estimated glomerular filtration rate (
31015462
)
Inflammatory bowel disease (
23128233
28067908
)
Lipoprotein (a) levels (
33730874
)
Meat-related diet (
32066663
)
Prostate cancer (
23535732
)
Refractive error (
32231278
)
Ulcerative colitis (
28067908
)
Interacting Genes
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPRASP3
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
46 interacting genes:
AGR3
AIG1
AQP1
ARFGAP3
BNIP2
C14orf180
CALN1
CIAO2A
CLN6
EMD
FRMD8
GAD2
GOSR2
GRB2
LCK
LHFPL5
LPAR3
LYN
MAN2B2
MEST
MIEF2
NDRG4
NINJ1
PBX3
PKMYT1
PLCG2
PNPO
PTPN9
RTP2
SEC22C
SLC41A2
SNAP47
SNX1
STX6
STX7
TBRG4
TMBIM6
TMEM143
TMEM243
TMEM74
TMEM86B
TMEM97
TRAF3IP3
UNC93B1
UPK2
ZFPL1
Entrez ID
358
54923
HPRD ID
00140
07904
Ensembl ID
ENSG00000240583
ENSG00000203896
Uniprot IDs
A0A024RA31
P29972
A0A087WT39
Q9H400
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
7UZE
8CT2
8CTE
Enriched GO Terms of Interacting Partners
?
Intermediate Filament
Keratin Filament
Protein Binding
Identical Protein Binding
Negative Regulation Of Lens Fiber Cell Differentiation
Hair Cycle
Regulation Of Lens Fiber Cell Differentiation
Tumor Necrosis Factor Receptor Binding
Cellular Developmental Process
Membrane
SNAP Receptor Activity
SNARE Complex
B Cell Receptor Signaling Pathway
Organelle Fusion
Lysosome
Ephrin Receptor Binding
Regulation Of Cellular Localization
Vesicle Organization
Plasma Membrane
Organelle Membrane Fusion
Vesicle Fusion
Protein Binding
Phosphotyrosine Residue Binding
T Cell Costimulation
Positive Regulation Of Immune Response
Immune Response-activating Signaling Pathway
Phosphorylation-dependent Protein Binding
Syntaxin Binding
Fc Receptor Signaling Pathway
Golgi Apparatus
Vesicle Docking
Spindle Pole Centrosome
Antigen Receptor-mediated Signaling Pathway
Endomembrane System
SNARE Binding
Immune Response-regulating Signaling Pathway
Membrane Fusion
Vesicle-mediated Transport
Activation Of Immune Response
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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