LIME1 and ARFGAP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LIME1	ARFGAP3
Description		Lck interacting transmembrane adaptor 1	ARF GTPase activating protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane B Cell Receptor Complex	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Membrane
	Molecular Function	Protein Binding Protein Kinase Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Adaptive Immune Response Immune System Process Regulation Of Transcription By RNA Polymerase II Regulation Of Canonical NF-kappaB Signal Transduction T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Non-canonical NF-kappaB Signal Transduction	Intracellular Protein Transport Protein Secretion Protein Transport Vesicle-mediated Transport COPI Coating Of Golgi Vesicle
Pathways			COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic CDC42 GTPase cycle RHOG GTPase cycle
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Bell's palsy ( 33602968) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 23128233 28067908) Lipoprotein (a) levels ( 33730874) Meat-related diet ( 32066663) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)	Resting metabolic rate ( 28476931)
Interacting Genes		46 interacting genes: AGR3 AIG1 AQP1 ARFGAP3 BNIP2 C14orf180 CALN1 CIAO2A CLN6 EMD FRMD8 GAD2 GOSR2 GRB2 LCK LHFPL5 LPAR3 LYN MAN2B2 MEST MIEF2 NDRG4 NINJ1 PBX3 PKMYT1 PLCG2 PNPO PTPN9 RTP2 SEC22C SLC41A2 SNAP47 SNX1 STX6 STX7 TBRG4 TMBIM6 TMEM143 TMEM243 TMEM74 TMEM86B TMEM97 TRAF3IP3 UNC93B1 UPK2 ZFPL1	10 interacting genes: APP CD14 CFTR CXCL8 LIME1 RTN4IP1 SMAD2 SNCA SYPL1 ZDHHC17
Entrez ID		54923	26286
HPRD ID		07904	06444
Ensembl ID		ENSG00000203896	ENSG00000242247
Uniprot IDs		A0A087WT39 Q9H400	Q9NP61
PDB IDs			2CRW
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity SNARE Complex B Cell Receptor Signaling Pathway Organelle Fusion Lysosome Ephrin Receptor Binding Regulation Of Cellular Localization Vesicle Organization Plasma Membrane Organelle Membrane Fusion Vesicle Fusion Protein Binding Phosphotyrosine Residue Binding T Cell Costimulation Positive Regulation Of Immune Response Immune Response-activating Signaling Pathway Phosphorylation-dependent Protein Binding Syntaxin Binding Fc Receptor Signaling Pathway Golgi Apparatus Vesicle Docking Spindle Pole Centrosome Antigen Receptor-mediated Signaling Pathway Endomembrane System SNARE Binding Immune Response-regulating Signaling Pathway Membrane Fusion Vesicle-mediated Transport Activation Of Immune Response	Response To Interleukin-1 Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Calcium Ion Transmembrane Transport Regulation Of Presynapse Organization Regulation Of Monoatomic Ion Transport Regulation Of Long-term Neuronal Synaptic Plasticity Response To Growth Factor Positive Regulation Of Endocytosis Regulation Of Presynapse Assembly Regulation Of Monoatomic Ion Transmembrane Transport Endocytosis Myeloid Leukocyte Activation Regulation Of Neurotransmitter Uptake Regulation Of Cell Communication Cellular Response To Copper Ion Regulation Of Signaling Response To Lipid Golgi-associated Vesicle Membrane Amyloid Fibril Formation Microglial Cell Activation Receptor-mediated Endocytosis Cellular Response To Fibroblast Growth Factor Stimulus Cytoplasmic Vesicle Membrane Response To Copper Ion Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Vesicle-mediated Transport Leukocyte Activation Involved In Inflammatory Response Regulation Of Calcium Ion Transport Response To Fibroblast Growth Factor Import Into Cell Tau Protein Binding Amyloid-beta Complex Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Regulation Of Signal Transduction Macrophage Activation Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To CAMP Regulation Of Monoatomic Cation Transmembrane Transport Opsonin Receptor Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Desipramine
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?