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AQP1 and KRT40
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
AQP1
KRT40
Gene Name
aquaporin 1 (Colton blood group)
keratin 40, type I
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Axon Terminus
Apical Part Of Cell
Extracellular Vesicular Exosome
Intermediate Filament
Molecular Function
Intracellular CGMP Activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Glycerol Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Ephrin Receptor Binding
Structural Molecule Activity
Biological Process
Renal Water Homeostasis
Glomerular Filtration
Renal Water Transport
CGMP Biosynthetic Process
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Cellular Water Homeostasis
Positive Regulation Of Lamellipodium Assembly
Positive Regulation Of Epithelial Cell Migration
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Sensory Perception Of Pain
Cellular Homeostasis
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Secretory Granule Organization
Cellular Response To Stress
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Wound Healing
Odontogenesis
Response To Drug
Hyperosmotic Salinity Response
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Estrogen
Lipid Digestion
Small Molecule Metabolic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Camera-type Eye Morphogenesis
Multicellular Organismal Water Homeostasis
Corticotropin Secretion
Transmembrane Transport
Renal Water Absorption
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Metanephric Glomerulus Vasculature Development
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Cation Transmembrane Transport
Pathways
O2/CO2 exchange in erythrocytes
Erythrocytes take up carbon dioxide and release oxygen
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Erythrocytes take up oxygen and release carbon dioxide
Aquaporin-mediated transport
Drugs
Acetazolamide
Diseases
GWAS
Nephrolithiasis (
22396660
)
Protein-Protein Interactions
42 interactors:
ADAMTSL4
CCDC136
CCDC36
CCDC57
CCDC85B
CEP44
CRTAC1
CSRNP1
EFEMP2
EPHB2
FOS
FSD2
IKZF2
IKZF3
KCTD17
KCTD9
KIAA1958
KRT31
KRT33B
KRT40
KRTAP10-3
KRTAP10-7
KRTAP4-12
KRTAP4-2
KRTAP9-2
MDFI
MID2
MTUS2
NBPF22P
NOTCH2NL
PICK1
RGS17
RGS20
RIMBP3
SIAH1
SPRY2
TCF4
TNK2
TRAF1
TRAF2
TRIM23
TRIP6
313 interactors:
ADAMTSL3
AEN
AES
AKAP17A
ALDH3B1
ALS2CR11
ANKRD36BP1
AP1M1
AQP1
AQP5
ARID5A
ARMC7
ARSI
ASMTL
ATPAF2
AVPI1
BAHD1
BARD1
BCAS2
BEX2
BMS1P5
BYSL
C10orf62
C11orf87
C14orf105
C19orf57
C19orf66
C19orf73
C1orf109
C1orf216
C20orf195
C22orf46
C5orf60
C6orf165
C6orf226
C8orf48
CA6
CARD9
CATIP
CBX8
CCDC112
CCDC120
CCDC146
CCDC185
CCDC26
CCDC93
CCER1
CCHCR1
CCNG1
CD33
CDC20B
CDK18
CDK5R1
CELA2B
CEP57
CEP57L1
CHCHD2
CHCHD3
CHIC2
CLEC18A
CNTF
COL8A1
COMT
COX5A
CREB5
CTSZ
CWF19L2
CYCS
CYTH4
DAAM2
DCDC2B
DCX
DDX6
DLGAP2
DMRT3
DOCK2
DOCK8
DTNB
EIF4E2
EXOC3-AS1
FAM107A
FAM124B
FAM214A
FAM27E3
FAM64A
FAM71C
FAM74A4
FAM90A1
FARS2
FASLG
FBF1
FBXL18
FBXO34
FBXW5
FKBP1B
FOXB1
FRG1
GATA2
GATAD2A
GEM
GFOD1
GGN
GLIDR
GNAI2
GNG5
GOLGA6L2
GPATCH2L
GTF3C5
GUCD1
HAUS1
HBA2
HBZ
HCK
HDAC4
HGS
HOXA1
HSPA12B
HSPD1
ING5
INPP5D
IQUB
ISCU
ITGB5
JOSD1
KAT5
KCTD9
KIFC3
KLHL38
KPNA2
KRT2
KRT20
KRT4
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT8
KRT81
LAGE3
LCE3E
LENG1
LIMS2
LIN37
LINC00636
LINC01588
LMF2
LMO1
LMO2
LMO4
LOC149950
LRCH4
MAB21L2
MAGOHB
MAPKBP1
MARK4
MED8
METTL17
MFAP1
MOB3C
MOS
MRPL11
MTA1
MXI1
NAB2
NAPRT
NDEL1
NEK6
NFKBID
NINJ1
NPBWR2
NPPB
NR1D2
NXF1
OPCML
OTUB2
PDLIM5
PGLS
PHF21A
PIGS
PIN1
PKD2
POLDIP3
POLL
POM121L8P
POP5
PPP1R18
PRAM1
PRKAA1
PRKAB2
PRPF31
PSMA1
PSMC5
PTGER3
PTPMT1
PXMP2
QPRT
RAB3IL1
RAB3IP
RAC1
RASSF5
RBM41
RCOR3
RECK
RNF213
RPL11
RSPH14
RTP5
RWDD2B
SCOC
SEMA4C
SETD5
SH2D4A
SHC3
SIRPA
SLC25A10
SLIRP
SLU7
SMARCE1
SMCO4
SNAI1
SNHG11
SNRPB
SNW1
SPATA24
SPEF1
SPG7
SRSF2
SSX2
SSX2IP
SYT6
TAPBPL
TBC1D16
TBC1D22B
TCEA2
TCEB3
TCHP
THAP7
TIE1
TMEM231
TMEM241
TMSB4X
TNIP3
TNNT1
TRAF4
TRIM42
TROAP
TRPV6
TSC22D4
TSGA10IP
TSHZ3
TTC23
TTC25
TTLL10
TXLNA
TXN2
TXNDC5
TYK2
TYRO3
UACA
UBASH3A
UCMA
USHBP1
USP2
USP21
UTP14C
UTP23
UXT
WDR25
WT1
WT1-AS
ZBTB16
ZBTB24
ZBTB38
ZC2HC1C
ZFHX3
ZFP2
ZFP69B
ZFYVE21
ZFYVE26
ZGPAT
ZMAT2
ZNF101
ZNF124
ZNF138
ZNF165
ZNF20
ZNF202
ZNF230
ZNF250
ZNF26
ZNF266
ZNF286A
ZNF317
ZNF329
ZNF337
ZNF417
ZNF439
ZNF446
ZNF488
ZNF490
ZNF564
ZNF569
ZNF581
ZNF587
ZNF625
ZNF655
ZNF697
ZNF702P
ZNF792
ZNF844
ZNRF2P1
ZSCAN21
Entrez ID
358
125115
HPRD ID
00140
08304
Ensembl ID
ENSG00000240583
ENSG00000204889
Uniprot IDs
B4DPF5
B4E3E3
P29972
Q6A162
PDB IDs
1FQY
1H6I
1IH5
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Signaling
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Regulation Of Binding
Developmental Process
Regulation Of Gene Expression
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Dendritic Spine Organization
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Signal Transduction
Axonal Fasciculation
Embryonic Organ Morphogenesis
Regulation Of Signal Transduction
Signal Transduction
Regulation Of Protein Binding
Cell Differentiation
Regulation Of Cellular Process
Face Morphogenesis
Neuron Recognition
Regulation Of Apoptotic Process
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Head Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Signaling
Regulation Of Cell Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway
Cell Communication
Negative Regulation Of Signaling
Face Development
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Nucleocytoplasmic Transport
Cellular Response To Extracellular Stimulus
Embryonic Organ Development
I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Fat Cell Differentiation
Body Morphogenesis
DNA Methylation
TRIF-dependent Toll-like Receptor Signaling Pathway
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Intracellular Signal Transduction
Termination Of G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Protein Binding
MyD88-independent Toll-like Receptor Signaling Pathway
Termination Of Signal Transduction
Toll-like Receptor 3 Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Cellular Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Developmental Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Defense Response To Virus By Virus
Regulation Of Cell Death
Regulation Of Protein Metabolic Process
Anatomical Structure Development
Regulation Of Apoptotic Process
Bicarbonate Transport
Cell Death
Death
Centrosome Organization
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Intermediate Filament Cytoskeleton Organization
Cytoskeleton Organization
Microtubule Organizing Center Organization
Positive Regulation Of Cellular Protein Metabolic Process
Intermediate Filament-based Process
Organelle Organization
Multicellular Organismal Development
Tagcloud
?
2cl
absorption
acclimation
bumetanide
circuit
cl
cotransporter
eel
exchanger
gn
governed
guanylin
hco3
intestine
isc
mi
ncc
nccbeta
nkcc
nkcc2beta
nullified
player
remainder
seawater
slc26a6
teleost
transporters
versa
vice
Tagcloud (Difference)
?
2cl
absorption
acclimation
bumetanide
circuit
cl
cotransporter
eel
exchanger
gn
governed
guanylin
hco3
intestine
isc
mi
ncc
nccbeta
nkcc
nkcc2beta
nullified
player
remainder
seawater
slc26a6
teleost
transporters
versa
vice
Tagcloud (Intersection)
?