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AQP1 and EPHB2
Number of citations of the paper that reports this interaction (PubMedID
10839360
)
0
Data Source:
HPRD
(two hybrid, in vivo)
AQP1
EPHB2
Description
aquaporin 1 (Colton blood group)
EPH receptor B2
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Brush Border
Basal Plasma Membrane
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Axon
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Ankyrin-1 Complex
Extracellular Region
Nucleoplasm
Cytosol
Plasma Membrane
Cell Surface
Membrane
Axon
Dendrite
Presynaptic Membrane
Cell Projection
Neuronal Cell Body
Dendritic Spine
Postsynaptic Membrane
Hippocampal Mossy Fiber To CA3 Synapse
Postsynapse
Glutamatergic Synapse
Molecular Function
Intracellularly CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Channel Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Ephrin Receptor Binding
Hydrogen Peroxide Channel Activity
Nucleotide Binding
Amyloid-beta Binding
Protein Kinase Activity
Protein Tyrosine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Ephrin Receptor Activity
Transmembrane-ephrin Receptor Activity
Signaling Receptor Binding
Protein Binding
ATP Binding
Axon Guidance Receptor Activity
Kinase Activity
Transferase Activity
Signaling Receptor Activity
Identical Protein Binding
Protein-containing Complex Binding
Biological Process
Renal Water Homeostasis
Glomerular Filtration
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Intracellular Water Homeostasis
Fibroblast Migration
Positive Regulation Of Fibroblast Migration
Carbon Dioxide Transport
Glycerol Transmembrane Transport
Cell Migration
Sensory Perception Of Pain
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Secretion By Cell
Cerebrospinal Fluid Secretion
Secretory Granule Organization
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Wound Healing
Odontogenesis
Negative Regulation Of Apoptotic Process
Lipid Digestion
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Camera-type Eye Morphogenesis
Defense Response To Gram-negative Bacterium
Multicellular Organismal-level Water Homeostasis
Corticotropin Secretion
Establishment Of Localization In Cell
Transmembrane Transport
Renal Water Absorption
Cellular Response To Hydrogen Peroxide
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Metanephric Glomerulus Vasculature Development
Ammonium Transmembrane Transport
Hydrogen Peroxide Transmembrane Transport
Monoatomic Cation Transmembrane Transport
Cell Morphogenesis
Angiogenesis
Urogenital System Development
Positive Regulation Of Immunoglobulin Production
Negative Regulation Of Cell Adhesion
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Nervous System Development
Axonogenesis
Axon Guidance
Axonal Fasciculation
Learning Or Memory
Learning
Animal Organ Morphogenesis
Positive Regulation Of Gene Expression
Phosphorylation
Peptidyl-tyrosine Phosphorylation
Optic Nerve Morphogenesis
Hindbrain Tangential Cell Migration
Central Nervous System Projection Neuron Axonogenesis
Corpus Callosum Development
Regulation Of Blood Coagulation
Positive Regulation Of Cell Migration
Positive Regulation Of B Cell Proliferation
Retinal Ganglion Cell Axon Guidance
Positive Regulation Of Synaptic Plasticity
Positive Regulation Of Tumor Necrosis Factor Production
B Cell Activation
Inner Ear Morphogenesis
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Ras Protein Signal Transduction
Ephrin Receptor Signaling Pathway
Regulation Of Neuronal Synaptic Plasticity
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Camera-type Eye Morphogenesis
Regulation Of Axonogenesis
Negative Regulation Of Axonogenesis
Regulation Of Body Fluid Levels
Positive Regulation Of Multicellular Organismal Process
Regulation Of Filopodium Assembly
Regulation Of Synapse Assembly
Positive Regulation Of Synapse Assembly
Roof Of Mouth Development
Dendritic Spine Development
Dendritic Spine Morphogenesis
Positive Regulation Of Dendritic Spine Morphogenesis
Negative Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Lipopolysaccharide
Commissural Neuron Axon Guidance
Postsynaptic Membrane Assembly
Neuron Projection Retraction
Vesicle-mediated Intercellular Transport
Tight Junction Assembly
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Long-term Synaptic Potentiation
Negative Regulation Of Glutamate Receptor Signaling Pathway
Positive Regulation Of Glutamate Receptor Signaling Pathway
Positive Regulation Of Protein Localization To Plasma Membrane
Cellular Response To Amyloid-beta
Neuron Projection Maintenance
Positive Regulation Of Protein Localization To Cell Surface
Regulation Of T-helper 17 Type Immune Response
Regulation Of Autophagosome Assembly
Regulation Of Behavioral Fear Response
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Developmental Lineage of Pancreatic Ductal Cells
EPH-Ephrin signaling
EPH-Ephrin signaling
L1CAM interactions
EPHB-mediated forward signaling
EPHB-mediated forward signaling
Ephrin signaling
Ephrin signaling
EPH-ephrin mediated repulsion of cells
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Phosphoaminophosphonic Acid-Adenylate Ester
Fostamatinib
Oleandrin
Diseases
GWAS
Fractures (
30598549
)
Heel bone mineral density (
28869591
30598549
)
hemolysis of donated blood (osmotic) (
34014839
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Triglyceride levels (
34074324
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Blood protein levels (
30072576
)
Refractive error (
32231278
)
Triiodothyronine levels (
30843173
)
Triiodothyronine levels and thyroxine levels (
30843173
)
Interacting Genes
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPRASP3
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
40 interacting genes:
ABL1
ABL2
ACP1
AFDN
APP
AQP1
ARHGEF6
CRK
EFNA5
EFNB1
EFNB2
ERF
FBXO7
FOS
GRB2
GRIN1
GRIN2B
ITSN1
KALRN
KSR1
MMP2
MMP9
MTMR14
NCK1
PICK1
PLCG1
PTK2
RASA1
RNF186
RRAS
RYK
SDC2
SDCBP
SH2D3C
SRC
SYNJ1
TRIM54
VAV2
VEGFA
YES1
Entrez ID
358
2048
HPRD ID
00140
02997
Ensembl ID
ENSG00000240583
ENSG00000133216
Uniprot IDs
A0A024RA31
P29972
B4DSE0
P29323
Q6NVW1
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
7UZE
8CT2
8CTE
1B4F
1F0M
2QBX
3ZFM
8EBL
Enriched GO Terms of Interacting Partners
?
Intermediate Filament
Keratin Filament
Protein Binding
Identical Protein Binding
Negative Regulation Of Lens Fiber Cell Differentiation
Hair Cycle
Regulation Of Lens Fiber Cell Differentiation
Tumor Necrosis Factor Receptor Binding
Cellular Developmental Process
Ephrin Receptor Signaling Pathway
Ephrin Receptor Binding
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Signal Transduction
Phosphotyrosine Residue Binding
Cell Surface Receptor Signaling Pathway
Regulation Of Locomotion
Regulation Of Cell Adhesion
Regulation Of Cellular Component Organization
Plasma Membrane Bounded Cell Projection Organization
Cell Migration
Cell Projection Organization
Positive Regulation Of Cell Migration
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Cell Motility
Positive Regulation Of Cell Adhesion
Regulation Of Cell-cell Adhesion
Plasma Membrane
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cell Migration
Regulation Of Cell Projection Organization
Fc Receptor Mediated Stimulatory Signaling Pathway
Intracellular Signal Transduction
Regulation Of Organelle Organization
Fc Receptor Signaling Pathway
Intracellular Signaling Cassette
Regulation Of Cell Motility
Cellular Developmental Process
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Multicellular Organismal Process
Fc-gamma Receptor Signaling Pathway
Regulation Of Cell-matrix Adhesion
Regulation Of Signal Transduction
ERBB Signaling Pathway
Regulation Of Endocytosis
Positive Regulation Of Immune System Process
Regulation Of Cell-substrate Adhesion
Regulation Of Signaling
Regulation Of Cell Communication
Regulation Of Biological Quality
Regulation Of Neuron Projection Development
Regulation Of Anatomical Structure Morphogenesis
Cellular Response To Oxygen-containing Compound
Cell Differentiation
Non-membrane Spanning Protein Tyrosine Kinase Activity
Positive Regulation Of Multicellular Organismal Process
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Tagcloud (Difference)
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Tagcloud (Intersection)
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